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Entry version 128 (12 Aug 2020)
Sequence version 1 (05 Jul 2004)
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Protein

TBC1 domain family member 31

Gene

Tbc1d31

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TBC1 domain family member 31
Alternative name(s):
Protein 4-B-3
WD repeat-containing protein 67
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tbc1d31
Synonyms:Wdr67
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2684931, Tbc1d31

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000514211 – 996TBC1 domain family member 31Add BLAST996

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6NXY1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6NXY1

PRoteomics IDEntifications database

More...
PRIDEi
Q6NXY1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6NXY1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6NXY1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022364, Expressed in blastocyst and 203 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6NXY1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6NXY1, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
229163, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q6NXY1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000022992

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6NXY1, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati33 – 74WD 1Add BLAST42
Repeati75 – 116WD 2Add BLAST42
Repeati117 – 157WD 3Add BLAST41
Repeati158 – 200WD 4Add BLAST43
Repeati201 – 248WD 5Add BLAST48
Repeati249 – 296WD 6Add BLAST48
Repeati297 – 334WD 7Add BLAST38
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini424 – 599Rab-GAP TBCPROSITE-ProRule annotationAdd BLAST176

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili388 – 414Sequence analysisAdd BLAST27
Coiled coili699 – 844Sequence analysisAdd BLAST146

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil, Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0295, Eukaryota
KOG1093, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153859

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003330_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6NXY1

Identification of Orthologs from Complete Genome Data

More...
OMAi
WFEYHPL

Database of Orthologous Groups

More...
OrthoDBi
858041at2759

TreeFam database of animal gene trees

More...
TreeFami
TF324799

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000195, Rab-GTPase-TBC_dom
IPR035969, Rab-GTPase_TBC_sf
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00566, RabGAP-TBC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320, WD40, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47923, SSF47923, 1 hit
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50086, TBC_RABGAP, 1 hit
PS00678, WD_REPEATS_1, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6NXY1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQSTDLGNKE SGKIWHRKPS PATHDGIIVN IVHSTSEYHP KVLRFLNVAF
60 70 80 90 100
DGSGDSFIAG DHQGNIYVFD LHGNRFNLVQ RTAQACTALA FNLRRKSEFL
110 120 130 140 150
VALADYSIKC FDTVTKELVS WMRGHESSVC SISVHASGRY AITTSSDTAQ
160 170 180 190 200
LWDLDTFQRK RKLNIRQSVG IQKVFFLPLS NTILSCFKDN SIFAWECDTL
210 220 230 240 250
FCKYQLPGPP EGSNILYKVF AVTRDGRILA AGGKSNHLHL WCLEATGLFR
260 270 280 290 300
IIQMPAKVRA VRHLEFLPDS FDAGSNQVLG VLSQDGIMRF VNIQTCKLLF
310 320 330 340 350
EIGTVEEGIS SSVISPHGRY IASIMENGSL NVYSVQALTQ EINKPPPPLV
360 370 380 390 400
KVIEDLPSNT VSSSNLKMKI MPGRVQRPAR CKESKIPTRV LKQDLTGDLE
410 420 430 440 450
NKENELSEGL NKKRLQILLK GYGEYPTKYR MFIWRSLLQL PENHTAFSSL
460 470 480 490 500
VDKGTHAAYL SLQKKYPIKS RKLLRVLQRT LSALAHWSAI FSDTPYLPLL
510 520 530 540 550
AFPFVKLFQN NQLICFEVVA TLIINWCQHW FEYFPNPPIN ILSMIENVLA
560 570 580 590 600
FHDKELLQHF IDRDITSQVY AWPLLETLFS EVLTREEWLR LFDNIFSNHP
610 620 630 640 650
SFLLMTVVAY STCSRAPLLN CTLKNDFEYF FHHRNNLDIN VVIREVYHLM
660 670 680 690 700
ETTPADIHPN SMLDAFVALT KGQYPIFNQY PKFIVDYQTR EWERIRNDEL
710 720 730 740 750
DFLRERQTVE NMQAEVDEQR AKDEAWYQKQ ELLRRAEETR REILLQEEEK
760 770 780 790 800
MAQQRQRLAA VKRELEIKEI HLQDAARRRL LKLQQDQREM ELRRLEDEIE
810 820 830 840 850
RKVQMRDQEI AATAKDLEIR QLELEAQKRL YEKDLTTSQE AVAKEIREDT
860 870 880 890 900
DAHRRKAALE EHMFQKLLEN SQMGGRRAQR WKEAEEKEFH LQSAKKASAL
910 920 930 940 950
SDASRKWFLR QETSAALEHE EMPWLQRQYM DSAYLPQTSR LHDVSDMDPS
960 970 980 990
THIFSRNYPT EWNHMEHDLL KNVRDLRRRL TARARNSCRH PHLLVT
Length:996
Mass (Da):115,838
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD7AD620F12F9A2B1
GO
Isoform 2 (identifier: Q6NXY1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-121: Missing.
     758-766: LAAVKRELE → CGPHDPAKT
     767-996: Missing.

Show »
Length:645
Mass (Da):74,616
Checksum:i788D8E8D75E0B09C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E0CYF4E0CYF4_MOUSE
TBC1 domain family member 31
Tbc1d31 Wdr67
49Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6T4B0F6T4B0_MOUSE
TBC1 domain family member 31
Tbc1d31 Wdr67
234Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD83881 differs from that shown. Intron retention.Curated
The sequence BAE32475 differs from that shown. Probable cloning artifact.Curated
The sequence BAE42193 differs from that shown. Probable cloning artifact.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti55D → N in AAH50039 (PubMed:15489334).Curated1
Sequence conflicti197C → R in AAH50039 (PubMed:15489334).Curated1
Sequence conflicti400E → G in BAE32475 (PubMed:16141072).Curated1
Sequence conflicti806R → G in AAH50039 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0161851 – 121Missing in isoform 2. 1 PublicationAdd BLAST121
Alternative sequenceiVSP_016186758 – 766LAAVKRELE → CGPHDPAKT in isoform 2. 1 Publication9
Alternative sequenceiVSP_016187767 – 996Missing in isoform 2. 1 PublicationAdd BLAST230

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK084542 mRNA Translation: BAC39214.1
AK154264 mRNA Translation: BAE32475.1 Sequence problems.
AK171024 mRNA Translation: BAE42193.1 Sequence problems.
BC050039 mRNA Translation: AAH50039.1
BC066830 mRNA Translation: AAH66830.1
AB185844 mRNA Translation: BAD83881.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37077.2 [Q6NXY1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001074865.2, NM_001081396.2 [Q6NXY1-1]
NP_001161151.1, NM_001167679.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000022992; ENSMUSP00000022992; ENSMUSG00000022364 [Q6NXY1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
210544

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:210544

UCSC genome browser

More...
UCSCi
uc007vss.1, mouse [Q6NXY1-1]
uc007vsy.1, mouse [Q6NXY1-4]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK084542 mRNA Translation: BAC39214.1
AK154264 mRNA Translation: BAE32475.1 Sequence problems.
AK171024 mRNA Translation: BAE42193.1 Sequence problems.
BC050039 mRNA Translation: AAH50039.1
BC066830 mRNA Translation: AAH66830.1
AB185844 mRNA Translation: BAD83881.1 Sequence problems.
CCDSiCCDS37077.2 [Q6NXY1-1]
RefSeqiNP_001074865.2, NM_001081396.2 [Q6NXY1-1]
NP_001161151.1, NM_001167679.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi229163, 2 interactors
IntActiQ6NXY1, 1 interactor
STRINGi10090.ENSMUSP00000022992

PTM databases

iPTMnetiQ6NXY1
PhosphoSitePlusiQ6NXY1

Proteomic databases

EPDiQ6NXY1
PaxDbiQ6NXY1
PRIDEiQ6NXY1

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
13779, 35 antibodies

Genome annotation databases

EnsembliENSMUST00000022992; ENSMUSP00000022992; ENSMUSG00000022364 [Q6NXY1-1]
GeneIDi210544
KEGGimmu:210544
UCSCiuc007vss.1, mouse [Q6NXY1-1]
uc007vsy.1, mouse [Q6NXY1-4]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
93594
MGIiMGI:2684931, Tbc1d31

Phylogenomic databases

eggNOGiKOG0295, Eukaryota
KOG1093, Eukaryota
GeneTreeiENSGT00940000153859
HOGENOMiCLU_003330_0_0_1
InParanoidiQ6NXY1
OMAiWFEYHPL
OrthoDBi858041at2759
TreeFamiTF324799

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
210544, 7 hits in 18 CRISPR screens

Protein Ontology

More...
PROi
PR:Q6NXY1
RNActiQ6NXY1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000022364, Expressed in blastocyst and 203 other tissues
ExpressionAtlasiQ6NXY1, baseline and differential
GenevisibleiQ6NXY1, MM

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR000195, Rab-GTPase-TBC_dom
IPR035969, Rab-GTPase_TBC_sf
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00566, RabGAP-TBC, 1 hit
SMARTiView protein in SMART
SM00320, WD40, 6 hits
SUPFAMiSSF47923, SSF47923, 1 hit
SSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50086, TBC_RABGAP, 1 hit
PS00678, WD_REPEATS_1, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTBC31_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NXY1
Secondary accession number(s): Q3TBW4
, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: July 5, 2004
Last modified: August 12, 2020
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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