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UniProtKB - Q6NXR0 (IIGP5_HUMAN)

Entry version 124 (07 Apr 2021)
Sequence version 1 (05 Jul 2004)
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Protein

Interferon-inducible GTPase 5

Gene

IRGC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi62 – 69GTP8
Nucleotide bindingi87 – 91GTP5
Nucleotide bindingi169 – 171GTP3
Nucleotide bindingi216 – 218GTP3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • GTPase activity Source: GO_Central
  • GTP binding Source: UniProtKB-KW
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q6NXR0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Interferon-inducible GTPase 5 (EC:3.6.5.-)
Alternative name(s):
Immunity-related GTPase cinema 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IRGC
Synonyms:IIGP5, IRGC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28835, IRGC

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6NXR0

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000124449.6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		56269

Open Targets

More...OpenTargetsi		ENSG00000124449

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671651

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6NXR0, Tbio

Chemistry databases

Drug and drug target database

More...DrugBanki		DB03814, 2-(N-morpholino)ethanesulfonic acid
DB04315, Guanosine-5'-Diphosphate

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		IRGC

Domain mapping of disease mutations (DMDM)

More...DMDMi		74736988

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002852651 – 463Interferon-inducible GTPase 5Add BLAST463

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei247PhosphoserineBy similarity1
Modified residuei304PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q6NXR0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6NXR0

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6NXR0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6NXR0

PeptideAtlas

More...PeptideAtlasi		Q6NXR0

PRoteomics IDEntifications database

More...PRIDEi		Q6NXR0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		66764

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6NXR0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6NXR0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000124449, Expressed in right testis and 43 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6NXR0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6NXR0, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000124449, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		121129, 19 interactors

Protein interaction database and analysis system

More...IntActi		Q6NXR0, 16 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000244314

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q6NXR0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q6NXR0

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini53 – 235IRG-type GPROSITE-ProRule annotationAdd BLAST183

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.PROSITE-ProRule annotationCurated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QS9R, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183007

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_015342_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6NXR0

Identification of Orthologs from Complete Genome Data

More...OMAi		GCSADKY

Database of Orthologous Groups

More...OrthoDBi		688334at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6NXR0

TreeFam database of animal gene trees

More...TreeFami		TF331897

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR030385, G_IRG_dom
IPR007743, Immunity-related_GTPase-like
IPR027417, P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05049, IIGP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51716, G_IRG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6NXR0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATSKLPVVP GEEENTILMA KERLEALRTA FESGDLPQAA SHLQELLAST 
        60         70         80         90        100
ESIRLEVGVT GESGAGKSSL INALRGLEAE DPGAALTGVM ETTMQPSPYP 
       110        120        130        140        150
HPQFPDVTLW DLPGAGSPGC PADKYLKQVD FSRYDFFLLV SPRRCGAVET 
       160        170        180        190        200
RLAAEILCQG KKFYFVRTKV DEDLAATRTQ RPSGFREAAV LQEIRDHCAE 
       210        220        230        240        250
RLREAGVADP RIFLVSNLSP ARYDFPTLVS TWEHDLPSHR RHAGLLSLPD 
       260        270        280        290        300
ISLEALQKKK AMLQEQVLKT ALVLGVIQAL PVPGLAAAYD DALLIHSLRG 
       310        320        330        340        350
YHRSFGLDDD SLAKLAEQVG KQAGDLRSVI RSPLANEVSP ETVLRLYSQS 
       360        370        380        390        400
SDGAMRVARA FERGIPVFGT LVAGGISFGA VYTMLQGCLN EMAEDAQRVR 
       410        420        430        440        450
IKALEDDEPQ PEVSLEVASD NGVEKGGSGE GGGEEAPLST CRKLGLLLKY 
       460 
ILDSWKKHDS EEK
Length:463
Mass (Da):50,288
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8ED3B06C512212D0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R0T1M0R0T1_HUMAN
Interferon-inducible GTPase 5
IRGC
275Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032008135D → N1 PublicationCorresponds to variant dbSNP:rs11555891Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC005622 Genomic DNA Translation: AAC34467.1
BC033853 mRNA Translation: AAH33853.1
BC066939 mRNA Translation: AAH66939.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12629.1

NCBI Reference Sequences

More...RefSeqi		NP_062558.1, NM_019612.3
XP_006723346.1, XM_006723283.3
XP_011525420.1, XM_011527118.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000244314; ENSP00000244314; ENSG00000124449

Database of genes from NCBI RefSeq genomes

More...GeneIDi		56269

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:56269

UCSC genome browser

More...UCSCi		uc002oxh.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005622 Genomic DNA Translation: AAC34467.1
BC033853 mRNA Translation: AAH33853.1
BC066939 mRNA Translation: AAH66939.1
CCDSiCCDS12629.1
RefSeqiNP_062558.1, NM_019612.3
XP_006723346.1, XM_006723283.3
XP_011525420.1, XM_011527118.2

3D structure databases

SMRiQ6NXR0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi121129, 19 interactors
IntActiQ6NXR0, 16 interactors
STRINGi9606.ENSP00000244314

Chemistry databases

DrugBankiDB03814, 2-(N-morpholino)ethanesulfonic acid
DB04315, Guanosine-5'-Diphosphate

PTM databases

iPTMnetiQ6NXR0
PhosphoSitePlusiQ6NXR0

Genetic variation databases

BioMutaiIRGC
DMDMi74736988

Proteomic databases

jPOSTiQ6NXR0
MassIVEiQ6NXR0
MaxQBiQ6NXR0
PaxDbiQ6NXR0
PeptideAtlasiQ6NXR0
PRIDEiQ6NXR0
ProteomicsDBi66764

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31099, 192 antibodies

Genome annotation databases

EnsembliENST00000244314; ENSP00000244314; ENSG00000124449
GeneIDi56269
KEGGihsa:56269
UCSCiuc002oxh.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		56269
DisGeNETi56269

GeneCards: human genes, protein and diseases

More...GeneCardsi		IRGC
HGNCiHGNC:28835, IRGC
HPAiENSG00000124449, Tissue enriched (testis)
neXtProtiNX_Q6NXR0
OpenTargetsiENSG00000124449
PharmGKBiPA142671651
VEuPathDBiHostDB:ENSG00000124449.6

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QS9R, Eukaryota
GeneTreeiENSGT00950000183007
HOGENOMiCLU_015342_2_0_1
InParanoidiQ6NXR0
OMAiGCSADKY
OrthoDBi688334at2759
PhylomeDBiQ6NXR0
TreeFamiTF331897

Enzyme and pathway databases

PathwayCommonsiQ6NXR0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		56269, 3 hits in 982 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		Interferon-inducible_GTPase_5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		56269
PharosiQ6NXR0, Tbio

Protein Ontology

More...PROi		PR:Q6NXR0
RNActiQ6NXR0, protein

Gene expression databases

BgeeiENSG00000124449, Expressed in right testis and 43 other tissues
ExpressionAtlasiQ6NXR0, baseline and differential
GenevisibleiQ6NXR0, HS

Family and domain databases

InterProiView protein in InterPro
IPR030385, G_IRG_dom
IPR007743, Immunity-related_GTPase-like
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF05049, IIGP, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51716, G_IRG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIIGP5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NXR0
Secondary accession number(s): Q05BR8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: July 5, 2004
Last modified: April 7, 2021
This is version 124 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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