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Protein

Armadillo repeat-containing protein 6

Gene

ARMC6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

It is uncertain whether Met-1 or Met-26 is the initiator.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • hematopoietic progenitor cell differentiation Source: GO_Central

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q6NXE6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Armadillo repeat-containing protein 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARMC6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000105676.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25049 ARMC6

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6NXE6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000105676

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134884604

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ARMC6

Domain mapping of disease mutations (DMDM)

More...
DMDMi
109940304

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002426601 – 501Armadillo repeat-containing protein 6Add BLAST501

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei64PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6NXE6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6NXE6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6NXE6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6NXE6

PeptideAtlas

More...
PeptideAtlasi
Q6NXE6

PRoteomics IDEntifications database

More...
PRIDEi
Q6NXE6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
66751
66752 [Q6NXE6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6NXE6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6NXE6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000105676 Expressed in 197 organ(s), highest expression level in right lobe of liver

CleanEx database of gene expression profiles

More...
CleanExi
HS_ARMC6

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6NXE6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6NXE6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA041420
HPA041681

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125026, 70 interactors

Protein interaction database and analysis system

More...
IntActi
Q6NXE6, 45 interactors

Molecular INTeraction database

More...
MINTi
Q6NXE6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000376148

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q6NXE6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6NXE6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati220 – 264ARM 1Add BLAST45
Repeati274 – 318ARM 2Add BLAST45
Repeati319 – 369ARM 3Add BLAST51
Repeati370 – 412ARM 4Add BLAST43

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ARMC6 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4199 Eukaryota
ENOG410XR4D LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000002913

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000290683

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG057500

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6NXE6

Identification of Orthologs from Complete Genome Data

More...
OMAi
WAIRNMV

Database of Orthologous Groups

More...
OrthoDBi
605325at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6NXE6

TreeFam database of animal gene trees

More...
TreeFami
TF324526

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR040104 ARMC6

The PANTHER Classification System

More...
PANTHERi
PTHR22895 PTHR22895, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00514 Arm, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00185 ARM, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50176 ARM_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 16 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6NXE6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSERCCSRYS SGASIGCTPT STQAKMVSKR IAQETFDAAV RENIEEFAMG
60 70 80 90 100
PEEAVKEAVE QFESQGVDLS NIVKTAPKVS ADGSQEPTHD ILQMLSDLQE
110 120 130 140 150
SVASSRPQEV SAYLTRFCDQ CKQDKACRFL AAQKGAYPII FTAWKLATAG
160 170 180 190 200
DQGLLLQSLN ALSVLTDGQP DLLDAQGLQL LVATLTQNAD EADLTCSGIR
210 220 230 240 250
CVRHACLKHE QNRQDLVKAG VLPLLTGAIT HHGHHTDVVR EACWALRVMT
260 270 280 290 300
FDDDIRVPFG HAHNHAKMIV QENKGLKVLI EATKAFLDNP GILSELCGTL
310 320 330 340 350
SRLAIRNEFC QEVVDLGGLS ILVSLLADCN DHQMRDQSGV QELVKQVLST
360 370 380 390 400
LRAIAGNDDV KDAIVRAGGT ESIVAAMTQH LTSPQVCEQS CAALCFLALR
410 420 430 440 450
KPDNSRIIVE GGGAVAALQA MKAHPQKAGV QKQACMLIRN LVAHGQAFSK
460 470 480 490 500
PILDLGAEAL IMQARSAHRD CEDVAKAALR DLGCHVELRE LWTGQRGNLA

P
Length:501
Mass (Da):54,142
Last modified:June 27, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i13813F0B99AF8AFF
GO
Isoform 2 (identifier: Q6NXE6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-25: Missing.

Note: Gene prediction based on EST data.
Show »
Length:476
Mass (Da):51,548
Checksum:i213563493D534278
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4E1N1B4E1N1_HUMAN
cDNA FLJ50945, highly similar to Ar...
ARMC6
408Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H4P3F5H4P3_HUMAN
Armadillo repeat-containing protein...
ARMC6
259Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5GWV0F5GWV0_HUMAN
Armadillo repeat-containing protein...
ARMC6
256Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H2X2F5H2X2_HUMAN
Armadillo repeat-containing protein...
ARMC6
161Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H2K4F5H2K4_HUMAN
Armadillo repeat-containing protein...
ARMC6
163Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YH65H0YH65_HUMAN
Armadillo repeat-containing protein...
ARMC6
145Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H6J3F5H6J3_HUMAN
Armadillo repeat-containing protein...
ARMC6
156Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YGQ5H0YGQ5_HUMAN
Armadillo repeat-containing protein...
ARMC6
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YGL0H0YGL0_HUMAN
Armadillo repeat-containing protein...
ARMC6
81Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H052F5H052_HUMAN
Armadillo repeat-containing protein...
ARMC6
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD03162 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAH67125 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0401031 – 25Missing in isoform 2. CuratedAdd BLAST25

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK295488 mRNA Translation: BAG58410.1
AC003038 Genomic DNA Translation: AAD03162.1 Sequence problems.
AC004447 Genomic DNA No translation available.
BC003700 mRNA Translation: AAH03700.1
BC067125 mRNA Translation: AAH67125.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32965.1 [Q6NXE6-2]
CCDS56089.1 [Q6NXE6-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001186125.1, NM_001199196.1 [Q6NXE6-1]
NP_219483.1, NM_033415.3 [Q6NXE6-2]
XP_005260214.1, XM_005260157.3 [Q6NXE6-2]
XP_016882974.1, XM_017027485.1 [Q6NXE6-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.77876

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000269932; ENSP00000269932; ENSG00000105676 [Q6NXE6-2]
ENST00000392335; ENSP00000376147; ENSG00000105676 [Q6NXE6-2]
ENST00000392336; ENSP00000376148; ENSG00000105676 [Q6NXE6-1]
ENST00000535612; ENSP00000444156; ENSG00000105676 [Q6NXE6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
93436

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:93436

UCSC genome browser

More...
UCSCi
uc002nlc.4 human [Q6NXE6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295488 mRNA Translation: BAG58410.1
AC003038 Genomic DNA Translation: AAD03162.1 Sequence problems.
AC004447 Genomic DNA No translation available.
BC003700 mRNA Translation: AAH03700.1
BC067125 mRNA Translation: AAH67125.1 Different initiation.
CCDSiCCDS32965.1 [Q6NXE6-2]
CCDS56089.1 [Q6NXE6-1]
RefSeqiNP_001186125.1, NM_001199196.1 [Q6NXE6-1]
NP_219483.1, NM_033415.3 [Q6NXE6-2]
XP_005260214.1, XM_005260157.3 [Q6NXE6-2]
XP_016882974.1, XM_017027485.1 [Q6NXE6-2]
UniGeneiHs.77876

3D structure databases

ProteinModelPortaliQ6NXE6
SMRiQ6NXE6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125026, 70 interactors
IntActiQ6NXE6, 45 interactors
MINTiQ6NXE6
STRINGi9606.ENSP00000376148

PTM databases

iPTMnetiQ6NXE6
PhosphoSitePlusiQ6NXE6

Polymorphism and mutation databases

BioMutaiARMC6
DMDMi109940304

Proteomic databases

EPDiQ6NXE6
jPOSTiQ6NXE6
MaxQBiQ6NXE6
PaxDbiQ6NXE6
PeptideAtlasiQ6NXE6
PRIDEiQ6NXE6
ProteomicsDBi66751
66752 [Q6NXE6-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000269932; ENSP00000269932; ENSG00000105676 [Q6NXE6-2]
ENST00000392335; ENSP00000376147; ENSG00000105676 [Q6NXE6-2]
ENST00000392336; ENSP00000376148; ENSG00000105676 [Q6NXE6-1]
ENST00000535612; ENSP00000444156; ENSG00000105676 [Q6NXE6-1]
GeneIDi93436
KEGGihsa:93436
UCSCiuc002nlc.4 human [Q6NXE6-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
93436
EuPathDBiHostDB:ENSG00000105676.13

GeneCards: human genes, protein and diseases

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GeneCardsi
ARMC6
HGNCiHGNC:25049 ARMC6
HPAiHPA041420
HPA041681
neXtProtiNX_Q6NXE6
OpenTargetsiENSG00000105676
PharmGKBiPA134884604

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG4199 Eukaryota
ENOG410XR4D LUCA
GeneTreeiENSGT00390000002913
HOGENOMiHOG000290683
HOVERGENiHBG057500
InParanoidiQ6NXE6
OMAiWAIRNMV
OrthoDBi605325at2759
PhylomeDBiQ6NXE6
TreeFamiTF324526

Enzyme and pathway databases

SignaLinkiQ6NXE6

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ARMC6 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ARMC6

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
93436

Protein Ontology

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PROi
PR:Q6NXE6

Gene expression databases

BgeeiENSG00000105676 Expressed in 197 organ(s), highest expression level in right lobe of liver
CleanExiHS_ARMC6
ExpressionAtlasiQ6NXE6 baseline and differential
GenevisibleiQ6NXE6 HS

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR040104 ARMC6
PANTHERiPTHR22895 PTHR22895, 1 hit
PfamiView protein in Pfam
PF00514 Arm, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 6 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARMC6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NXE6
Secondary accession number(s): B4DI98, O94999, Q9BTH5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: January 16, 2019
This is version 133 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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