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Entry version 139 (07 Apr 2021)
Sequence version 2 (20 Feb 2007)
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Protein

Kinesin-like protein KIF24

Gene

Kif24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. Following activation by NEK2 involved in disassembly of primary cilium during G2/M phase but does not disassemble fully formed ciliary axonemes. As cilium assembly and disassembly is proposed to coexist in a dynamic equilibrium may suppress nascent cilium assembly and, potentially, ciliar re-assembly in cells that have already disassembled their cilia ensuring the completion of cilium removal in the later stages of the cell cycle (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi308 – 315ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein
Biological processCilium biogenesis/degradation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-5620912, Anchoring of the basal body to the plasma membrane

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kinesin-like protein KIF24
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kif24
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1918345, Kif24

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002782491 – 1356Kinesin-like protein KIF24Add BLAST1356

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei102PhosphoserineBy similarity1
Modified residuei473PhosphoserineBy similarity1
Modified residuei579PhosphoserineCombined sources1
Modified residuei615Phosphothreonine; by NEK2By similarity1
Modified residuei616Phosphoserine; by NEK2By similarity1
Modified residuei640PhosphoserineCombined sources1
Modified residuei817PhosphoserineCombined sources1
Modified residuei820PhosphoserineCombined sources1
Modified residuei1008PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6NWW5

PeptideAtlas

More...
PeptideAtlasi
Q6NWW5

PRoteomics IDEntifications database

More...
PRIDEi
Q6NWW5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
263531 [Q6NWW5-1]
263532 [Q6NWW5-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6NWW5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6NWW5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in brain, spinal cord, and small intestine.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028438, Expressed in cardiac ventricle and 171 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6NWW5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6NWW5, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CCP110, CEP97, TALPID3.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000103690

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6NWW5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6NWW5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 64SAMPROSITE-ProRule annotationAdd BLAST64
Domaini218 – 541Kinesin motorPROSITE-ProRule annotationAdd BLAST324

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0246, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154046

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007560_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6NWW5

Identification of Orthologs from Complete Genome Data

More...
OMAi
WTDIPPH

Database of Orthologous Groups

More...
OrthoDBi
418348at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6NWW5

TreeFam database of animal gene trees

More...
TreeFami
TF336001

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 1 hit
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019821, Kinesin_motor_CS
IPR001752, Kinesin_motor_dom
IPR036961, Kinesin_motor_dom_sf
IPR027417, P-loop_NTPase
IPR001660, SAM
IPR013761, SAM/pointed_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00225, Kinesin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00380, KINESINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00129, KISc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769, SSF47769, 1 hit
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00411, KINESIN_MOTOR_1, 1 hit
PS50067, KINESIN_MOTOR_2, 1 hit
PS50105, SAM_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6NWW5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MASWLYECLC EAELAQYYPH FTALGLQKID ELAKVTMKDY SRLGVHDMND
60 70 80 90 100
RKRLFQLIKI IKIMQEEDKA LGIPEHPLQA SSLYTKPREF RSGPRRQLHF
110 120 130 140 150
DSPSASKDKM ANNETGSLSN FSVDEQKSTY LKVLEHMLPD DSQCQTKIRA
160 170 180 190 200
PDASAADASM QTETNAPLFS SNYFSPQLGN CDIPVIQRVS HVSGYNYGIP
210 220 230 240 250
HSCVRQITSE NPWTEMEKIR VCVRKRPLGV REVRRGEVNV ITVEDKETLL
260 270 280 290 300
VHEKKEAVDL TQYILQHVFY FDEVFGEACS NQDVYLKTAH PLIQHIFNGG
310 320 330 340 350
SATCFAYGQT GAGKTYTMIG THQNPGLYAL AAKDIFRQLK VSQSRRNLFV
360 370 380 390 400
WISFYEIYCG QLYDLLNRRK RLFAREDSKH VVQIAGLREL QVDSVELLLQ
410 420 430 440 450
VILKGSKERS TGATGVNADS SRSHAIIQIQ IKDSAKRTFG RISFIDLAGS
460 470 480 490 500
ERAADARDSD RQTKMEGAEI NQSLLALKEC IRALDQEHTH TPFRQSKLTQ
510 520 530 540 550
VLKDSFIGNA KTCMIANISP SHIATEHTLN TLRYADRVKE LKKGVKCCAS
560 570 580 590 600
ATSQNQTSAN ASPKRIQSSP VTLPGDKCSP KKVKLGLQQS LTVAPGPTKV
610 620 630 640 650
KAHPLASHVP NVPFTSGPKT PGKKSSSRGS PTPEWDMKAS PRKGTTRSGH
660 670 680 690 700
SIKKGAESAP LCSEKSQIGS KIAVGWEGRA SDPGEGLLRV RLPTRGKKVQ
710 720 730 740 750
PVQPVQKQLL SRPRLLANSH HLEATQDSKV GTPAGLAPEA WTNPILQQKE
760 770 780 790 800
REEHLRFYHQ QFQQPPLLKQ KLNYQPLQRL LCQHRPSEGR LQSETGFPLH
810 820 830 840 850
SNPENRDGAQ AEDLDDSDFS EDSFSHGSSQ PAMKQGSTAL ERSGSSFFLH
860 870 880 890 900
QDREHSPEEQ AAERQQCLLF SSETDGSKKR PADSWVYSRD PIISHRRGAL
910 920 930 940 950
SQSHSPSMVC PDWSKEEDSA SSGPSPKDNR AQKPSSSQVD FVHHQKPGEA
960 970 980 990 1000
QVSDIRLEAF TSEVPEQAEG SLSSPSPENG LSFPLSHVAV SGSPDQRDRV
1010 1020 1030 1040 1050
CTPLREVSEN RVTHTPGRVN SSTPFQEDSG EQIQMCSANA SGLMAPLTMS
1060 1070 1080 1090 1100
LLETPCHEDL SSLEQIAQDG AGYGFMAEIV GGPAAGHTVP SYDQEAALPV
1110 1120 1130 1140 1150
SSATECLWLS SSPPDNRPSG DLPALSPSPI HQHSPDKLPG REAYQTRRPI
1160 1170 1180 1190 1200
LLPENHMGSK LYDDRAEETE LGGSLTFPRK PSSNIHAGVP YSTPFLTSCT
1210 1220 1230 1240 1250
GSSNGVGRPW AQERKHPTGV SCQELVSSTD SNKPHYNEDI AWLRHRPISR
1260 1270 1280 1290 1300
CLDSDSPVVP SCSSKALRTY CPLTPEQAQQ VIIRAHKEQL DEMAELDLKE
1310 1320 1330 1340 1350
ETLMTQMDSN DFEDFVTQLD EIMALKSRCI QSLRSQLQLY LTSHRPAAAP

ERTVVS
Length:1,356
Mass (Da):150,207
Last modified:February 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCA1009620C23BF43
GO
Isoform 2 (identifier: Q6NWW5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     265-398: Missing.

Show »
Length:1,222
Mass (Da):134,855
Checksum:i7CBCEDE7C7BBDA72
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2BGK7A2BGK7_MOUSE
Kinesin-like protein KIF24
Kif24
141Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH67395 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAC39323 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti413A → T in BAC39323 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_023214265 – 398Missing in isoform 2. 1 PublicationAdd BLAST134

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK084967 mRNA Translation: BAC39323.1 Sequence problems.
AL807823 Genomic DNA No translation available.
BX470237 Genomic DNA No translation available.
BC067395 mRNA Translation: AAH67395.1 Different initiation.
AB054028 Genomic DNA Translation: BAB32492.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18060.2 [Q6NWW5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_077203.2, NM_024241.2 [Q6NWW5-1]
XP_006537612.1, XM_006537549.3 [Q6NWW5-1]
XP_011248205.1, XM_011249903.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000030148; ENSMUSP00000030148; ENSMUSG00000028438 [Q6NWW5-2]
ENSMUST00000108055; ENSMUSP00000103690; ENSMUSG00000028438 [Q6NWW5-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
109242

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:109242

UCSC genome browser

More...
UCSCi
uc008sio.1, mouse [Q6NWW5-1]
uc012dcb.1, mouse [Q6NWW5-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK084967 mRNA Translation: BAC39323.1 Sequence problems.
AL807823 Genomic DNA No translation available.
BX470237 Genomic DNA No translation available.
BC067395 mRNA Translation: AAH67395.1 Different initiation.
AB054028 Genomic DNA Translation: BAB32492.1
CCDSiCCDS18060.2 [Q6NWW5-1]
RefSeqiNP_077203.2, NM_024241.2 [Q6NWW5-1]
XP_006537612.1, XM_006537549.3 [Q6NWW5-1]
XP_011248205.1, XM_011249903.2

3D structure databases

SMRiQ6NWW5
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103690

PTM databases

iPTMnetiQ6NWW5
PhosphoSitePlusiQ6NWW5

Proteomic databases

PaxDbiQ6NWW5
PeptideAtlasiQ6NWW5
PRIDEiQ6NWW5
ProteomicsDBi263531 [Q6NWW5-1]
263532 [Q6NWW5-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
11186, 108 antibodies

Genome annotation databases

EnsembliENSMUST00000030148; ENSMUSP00000030148; ENSMUSG00000028438 [Q6NWW5-2]
ENSMUST00000108055; ENSMUSP00000103690; ENSMUSG00000028438 [Q6NWW5-1]
GeneIDi109242
KEGGimmu:109242
UCSCiuc008sio.1, mouse [Q6NWW5-1]
uc012dcb.1, mouse [Q6NWW5-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
347240
MGIiMGI:1918345, Kif24

Phylogenomic databases

eggNOGiKOG0246, Eukaryota
GeneTreeiENSGT00940000154046
HOGENOMiCLU_007560_0_0_1
InParanoidiQ6NWW5
OMAiWTDIPPH
OrthoDBi418348at2759
PhylomeDBiQ6NWW5
TreeFamiTF336001

Enzyme and pathway databases

ReactomeiR-MMU-5620912, Anchoring of the basal body to the plasma membrane

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
109242, 2 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Kif24, mouse

Protein Ontology

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PROi
PR:Q6NWW5
RNActiQ6NWW5, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000028438, Expressed in cardiac ventricle and 171 other tissues
ExpressionAtlasiQ6NWW5, baseline and differential
GenevisibleiQ6NWW5, MM

Family and domain databases

Gene3Di1.10.150.50, 1 hit
3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR019821, Kinesin_motor_CS
IPR001752, Kinesin_motor_dom
IPR036961, Kinesin_motor_dom_sf
IPR027417, P-loop_NTPase
IPR001660, SAM
IPR013761, SAM/pointed_sf
PfamiView protein in Pfam
PF00225, Kinesin, 1 hit
PRINTSiPR00380, KINESINHEAVY
SMARTiView protein in SMART
SM00129, KISc, 1 hit
SUPFAMiSSF47769, SSF47769, 1 hit
SSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411, KINESIN_MOTOR_1, 1 hit
PS50067, KINESIN_MOTOR_2, 1 hit
PS50105, SAM_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKIF24_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NWW5
Secondary accession number(s): A2BGK6, Q8BUI2, Q99PT7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: February 20, 2007
Last modified: April 7, 2021
This is version 139 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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