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UniProtKB - Q6NVY4 (Q6NVY4_HUMAN)
Protein
Submitted name:
BNIP3 protein
Gene
BNIP3
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- identical protein binding Source: UniProt
GO - Biological processi
- positive regulation of apoptotic process Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: BNIP3 proteinImported |
Gene namesi | Name:BNIP3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass membrane protein ARBA annotation
Mitochondrion
- mitochondrial envelope Source: InterPro
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 211 – 234 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
Membrane, MitochondrionARBA annotationStructurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 72 | DisorderedSequence analysisAdd BLAST | 72 | |
Regioni | 102 – 152 | DisorderedSequence analysisAdd BLAST | 51 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 46 – 72 | Polar residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 110 – 131 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 132 – 152 | Basic and acidic residuesSequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the NIP3 family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
OrthoDBi | 1250566at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR010548, BNIP3 |
PANTHERi | PTHR15186, PTHR15186, 1 hit |
Pfami | View protein in Pfam PF06553, BNIP3, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q6NVY4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GFLRPGCGAP LSPGAQLGRG APTSAFPPPA AEAHPAARRG LRSPQLPSGA
60 70 80 90 100
MSQNGAPGMQ EESLQGSWVE LHFSNNGNGG SVPASVSIYN GDMEKILLDA
110 120 130 140 150
QHESGRSSSK SSHCDSPPRS QTPQDTNRAS ETDTHSIGEK NSSQSEEDDI
160 170 180 190 200
ERRKEVESIL KKNSDWIWDW SSRPENIPPK EFLFKHPKRT ATLSMRNTSV
210 220 230 240
MKKGGIFSAE FLKVFLPSLL LSHLLAIGLG IYIGRRLTTS TSTF
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC067818 mRNA Translation: AAH67818.1 |
RefSeqi | NP_004043.3, NM_004052.3 |
Genome annotation databases
GeneIDi | 664 |
KEGGi | hsa:664 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC067818 mRNA Translation: AAH67818.1 |
RefSeqi | NP_004043.3, NM_004052.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q6NVY4 |
Protocols and materials databases
DNASUi | 664 |
Genome annotation databases
GeneIDi | 664 |
KEGGi | hsa:664 |
Organism-specific databases
CTDi | 664 |
Phylogenomic databases
OrthoDBi | 1250566at2759 |
Miscellaneous databases
BioGRID-ORCSi | 664, 128 hits in 1075 CRISPR screens |
ChiTaRSi | BNIP3, human |
GenomeRNAii | 664 |
Family and domain databases
InterProi | View protein in InterPro IPR010548, BNIP3 |
PANTHERi | PTHR15186, PTHR15186, 1 hit |
Pfami | View protein in Pfam PF06553, BNIP3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6NVY4_HUMAN | |
Accessioni | Q6NVY4Primary (citable) accession number: Q6NVY4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | May 25, 2022 | |
This is version 91 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |