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Protein

Cysteine-rich DPF motif domain-containing protein 1

Gene

CDPF1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine-rich DPF motif domain-containing protein 1
Gene namesi
Name:CDPF1
Synonyms:C22orf40
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000205643.10
HGNCiHGNC:33710 CDPF1
neXtProtiNX_Q6NVV7

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000205643
PharmGKBiPA162379006

Polymorphism and mutation databases

BioMutaiCDPF1
DMDMi74749009

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003413601 – 123Cysteine-rich DPF motif domain-containing protein 1Add BLAST123

Proteomic databases

EPDiQ6NVV7
MaxQBiQ6NVV7
PaxDbiQ6NVV7
PeptideAtlasiQ6NVV7
PRIDEiQ6NVV7
ProteomicsDBi66725

PTM databases

iPTMnetiQ6NVV7
PhosphoSitePlusiQ6NVV7

Expressioni

Gene expression databases

BgeeiENSG00000205643 Expressed in 131 organ(s), highest expression level in quadriceps femoris
CleanExiHS_C22orf40
ExpressionAtlasiQ6NVV7 baseline and differential
GenevisibleiQ6NVV7 HS

Organism-specific databases

HPAiHPA018823

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BHLHE40O145033EBI-2802782,EBI-711810

Protein-protein interaction databases

BioGridi127293, 3 interactors
IntActiQ6NVV7, 19 interactors

Structurei

3D structure databases

ProteinModelPortaliQ6NVV7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CDPF1 family.Curated

Phylogenomic databases

eggNOGiKOG4543 Eukaryota
ENOG4111ZD4 LUCA
GeneTreeiENSGT00390000007925
HOGENOMiHOG000006647
HOVERGENiHBG098217
InParanoidiQ6NVV7
OMAiCSFYYTA
OrthoDBiEOG091G0UFX
PhylomeDBiQ6NVV7
TreeFamiTF313933

Family and domain databases

InterProiView protein in InterPro
IPR018785 Cys-rich_DPF
PfamiView protein in Pfam
PF10170 C6_DPF, 1 hit
PRINTSiPR01995 UPF0595

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q6NVV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASHVECRPL GVFECELCTL TAPYSYVGQK PPNTQSMVLL EESYVMKDPF
60 70 80 90 100
TSDKDRFLVL GSCCSLCSRL VCVGPECSLF YSKRFCLPCV RENINAFPQE
110 120
IRQDLEKRKA PSKRTPSQPG SRT
Length:123
Mass (Da):13,877
Last modified:July 5, 2004 - v1
Checksum:i87E30A594058235F
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6RAJ7F6RAJ7_HUMAN
Cysteine-rich DPF motif domain-cont...
CDPF1
118Annotation score:
F6UL18F6UL18_HUMAN
Cysteine-rich DPF motif domain-cont...
CDPF1
115Annotation score:
H9KV78H9KV78_HUMAN
Cysteine-rich DPF motif domain-cont...
CDPF1
89Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti103Q → R in AAH45796 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_0440585V → A. Corresponds to variant dbSNP:rs9627281Ensembl.1
Natural variantiVAR_06223770L → R. Corresponds to variant dbSNP:rs55641018Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL078611 Genomic DNA No translation available.
CH471138 Genomic DNA Translation: EAW73407.1
BC045796 mRNA Translation: AAH45796.1
BC067871 mRNA Translation: AAH67871.1
CCDSiCCDS33670.1
RefSeqiNP_997210.3, NM_207327.4
XP_011528267.1, XM_011529965.2
UniGeneiHs.103110
Hs.592209

Genome annotation databases

EnsembliENST00000314567; ENSP00000325301; ENSG00000205643
GeneIDi150383
KEGGihsa:150383
UCSCiuc003bhe.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL078611 Genomic DNA No translation available.
CH471138 Genomic DNA Translation: EAW73407.1
BC045796 mRNA Translation: AAH45796.1
BC067871 mRNA Translation: AAH67871.1
CCDSiCCDS33670.1
RefSeqiNP_997210.3, NM_207327.4
XP_011528267.1, XM_011529965.2
UniGeneiHs.103110
Hs.592209

3D structure databases

ProteinModelPortaliQ6NVV7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127293, 3 interactors
IntActiQ6NVV7, 19 interactors

PTM databases

iPTMnetiQ6NVV7
PhosphoSitePlusiQ6NVV7

Polymorphism and mutation databases

BioMutaiCDPF1
DMDMi74749009

Proteomic databases

EPDiQ6NVV7
MaxQBiQ6NVV7
PaxDbiQ6NVV7
PeptideAtlasiQ6NVV7
PRIDEiQ6NVV7
ProteomicsDBi66725

Protocols and materials databases

DNASUi150383
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000314567; ENSP00000325301; ENSG00000205643
GeneIDi150383
KEGGihsa:150383
UCSCiuc003bhe.4 human

Organism-specific databases

CTDi150383
EuPathDBiHostDB:ENSG00000205643.10
GeneCardsiCDPF1
HGNCiHGNC:33710 CDPF1
HPAiHPA018823
neXtProtiNX_Q6NVV7
OpenTargetsiENSG00000205643
PharmGKBiPA162379006
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4543 Eukaryota
ENOG4111ZD4 LUCA
GeneTreeiENSGT00390000007925
HOGENOMiHOG000006647
HOVERGENiHBG098217
InParanoidiQ6NVV7
OMAiCSFYYTA
OrthoDBiEOG091G0UFX
PhylomeDBiQ6NVV7
TreeFamiTF313933

Miscellaneous databases

ChiTaRSiCDPF1 human
GenomeRNAii150383
PROiPR:Q6NVV7

Gene expression databases

BgeeiENSG00000205643 Expressed in 131 organ(s), highest expression level in quadriceps femoris
CleanExiHS_C22orf40
ExpressionAtlasiQ6NVV7 baseline and differential
GenevisibleiQ6NVV7 HS

Family and domain databases

InterProiView protein in InterPro
IPR018785 Cys-rich_DPF
PfamiView protein in Pfam
PF10170 C6_DPF, 1 hit
PRINTSiPR01995 UPF0595
ProtoNetiSearch...

Entry informationi

Entry nameiCDPF1_HUMAN
AccessioniPrimary (citable) accession number: Q6NVV7
Secondary accession number(s): A6NCA1
, A9IU12, A9IU16, Q3ZCR8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: July 5, 2004
Last modified: September 12, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  4. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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