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Protein

Isocitrate dehydrogenase [NAD] subunit, mitochondrial

Gene

idh3a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTricarboxylic acid cycleUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-71403 Citric acid cycle (TCA cycle)

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NAD] subunit, mitochondrialUniRule annotation
Gene namesi
Name:idh3aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 25

Organism-specific databases

ZFINiZDB-GENE-040426-1007 idh3a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MitochondrionUniRule annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000030278

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000094415

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 357Iso_dhInterPro annotationAdd BLAST326

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

eggNOGiKOG0785 Eukaryota
COG0473 LUCA
GeneTreeiENSGT00550000074918
HOGENOMiHOG000021113
HOVERGENiHBG052080
KOiK00030
OMAiFQQIQTR
OrthoDBiEOG091G094X
TreeFamiTF105692

Family and domain databases

InterProiView protein in InterPro
IPR019818 IsoCit/isopropylmalate_DH_CS
IPR004434 Isocitrate_DH_NAD
IPR024084 IsoPropMal-DH-like_dom
PfamiView protein in Pfam
PF00180 Iso_dh, 1 hit
SMARTiView protein in SMART
SM01329 Iso_dh, 1 hit
TIGRFAMsiTIGR00175 mito_nad_idh, 1 hit
PROSITEiView protein in PROSITE
PS00470 IDH_IMDH, 1 hit

Sequencei

Sequence statusi: Complete.

Q6NV33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANAWRSAVS CIMGAIKTQT PQPRVFSRGI QTVTLIPGDG IGPEISTAVM
60 70 80 90 100
KIFEAAKTPI QWEERNVTAI KGPGGRWMIP PEAKESMDKN KIGLKGPLKT
110 120 130 140 150
PIAAGHPSMN LLLRKTFDLY ANVRPCVSIE GYKTPYTDVD LVTIRENTEG
160 170 180 190 200
EYSGIEHVIV DGVVQSIKLI TEEASRRIAE YAFEYARNNQ RTSVTAVHKA
210 220 230 240 250
NIMRMSDGLF LRKCREVAEN FKDVKFTEMY LDTVCLNMVQ DPSQFDVLVM
260 270 280 290 300
PNLYGDILSD LCAGLIGGLG VTPSGNIGAN GVAIFESVHG TAPDIAGKDM
310 320 330 340 350
ANPTALLLSA VMMLRHMGLH GHAKKIETAC FDTIRDKKVL TKDLGGNSKC
360
SEFTADICRR VQDME
Length:365
Mass (Da):39,983
Last modified:July 5, 2004 - v1
Checksum:i4D77B53FD162CB2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR381664 Genomic DNA No translation available.
BC068333 mRNA Translation: AAH68333.1
RefSeqiNP_957245.2, NM_200951.2
UniGeneiDr.13580

Genome annotation databases

EnsembliENSDART00000103638; ENSDARP00000094415; ENSDARG00000030278
GeneIDi393926
KEGGidre:393926

Similar proteinsi

Entry informationi

Entry nameiQ6NV33_DANRE
AccessioniPrimary (citable) accession number: Q6NV33
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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