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Entry version 128 (29 Sep 2021)
Sequence version 2 (20 Mar 2007)
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Protein

Proactivator polypeptide-like 1

Gene

PSAPL1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May activate the lysosomal degradation of sphingolipids.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid metabolism, Sphingolipid metabolism

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6NUJ1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Proactivator polypeptide-like 1
Cleaved into the following 5 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PSAPL1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33131, PSAPL1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6NUJ1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000178597

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
768239

Open Targets

More...
OpenTargetsi
ENSG00000178597

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162400215

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6NUJ1, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PSAPL1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
134035030

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_000028030518 – 59By similarityAdd BLAST42
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028030661 – 144Saposin A-likeBy similarityAdd BLAST84
PropeptideiPRO_0000280307146 – 180By similarityAdd BLAST35
ChainiPRO_0000280308181 – 257Saposin B-Val-likeBy similarityAdd BLAST77
ChainiPRO_0000280309181 – 256Saposin B-likeBy similarityAdd BLAST76
PropeptideiPRO_0000280310259 – 288By similarityAdd BLAST30
ChainiPRO_0000280311290 – 369Saposin C-likeBy similarityAdd BLAST80
PropeptideiPRO_0000280312370 – 391By similarityAdd BLAST22
ChainiPRO_0000280313392 – 473Saposin D-likeBy similarityAdd BLAST82
PropeptideiPRO_0000280314474 – 521By similarityAdd BLAST48

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi64 ↔ 140PROSITE-ProRule annotation
Disulfide bondi67 ↔ 134PROSITE-ProRule annotation
Disulfide bondi95 ↔ 107PROSITE-ProRule annotation
Disulfide bondi184 ↔ 254PROSITE-ProRule annotation
Disulfide bondi187 ↔ 248PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi201N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi213 ↔ 224PROSITE-ProRule annotation
Disulfide bondi294 ↔ 366PROSITE-ProRule annotation
Disulfide bondi297 ↔ 360PROSITE-ProRule annotation
Glycosylationi311N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi325 ↔ 336PROSITE-ProRule annotation
Disulfide bondi396 ↔ 469PROSITE-ProRule annotation
Disulfide bondi399 ↔ 463PROSITE-ProRule annotation
Disulfide bondi427 ↔ 438PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6NUJ1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6NUJ1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6NUJ1

PeptideAtlas

More...
PeptideAtlasi
Q6NUJ1

PRoteomics IDEntifications database

More...
PRIDEi
Q6NUJ1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66682

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q6NUJ1, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6NUJ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6NUJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000178597, Expressed in mammalian vulva and 87 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6NUJ1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000178597, Group enriched (skin, stomach, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
612854, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000317445

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6NUJ1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6NUJ1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini19 – 59Saposin A-type 1PROSITE-ProRule annotationAdd BLAST41
Domaini60 – 144Saposin B-type 1PROSITE-ProRule annotationAdd BLAST85
Domaini180 – 258Saposin B-type 2PROSITE-ProRule annotationAdd BLAST79
Domaini290 – 370Saposin B-type 3PROSITE-ProRule annotationAdd BLAST81
Domaini392 – 473Saposin B-type 4PROSITE-ProRule annotationAdd BLAST82
Domaini475 – 515Saposin A-type 2PROSITE-ProRule annotationAdd BLAST41

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1340, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164031

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_033757_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6NUJ1

Identification of Orthologs from Complete Genome Data

More...
OMAi
KTCEWLP

Database of Orthologous Groups

More...
OrthoDBi
865505at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6NUJ1

TreeFam database of animal gene trees

More...
TreeFami
TF316942

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003119, SAP_A
IPR007856, SapB_1
IPR008138, SapB_2
IPR008373, Saposin
IPR011001, Saposin-like
IPR021165, Saposin_chordata
IPR008139, SaposinB_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02199, SapA, 2 hits
PF05184, SapB_1, 1 hit
PF03489, SapB_2, 2 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002431, Saposin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01797, SAPOSIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00162, SAPA, 2 hits
SM00741, SapB, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47862, SSF47862, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51110, SAP_A, 2 hits
PS50015, SAP_B, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q6NUJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLCALLLLPS LLGATRASPT SGPQECAKGS TVWCQDLQTA ARCGAVGYCQ
60 70 80 90 100
GAVWNKPTAK SLPCDVCQDI AAAAGNGLNP DATESDILAL VMKTCEWLPS
110 120 130 140 150
QESSAGCKWM VDAHSSAILS MLRGAPDSAP AQVCTALSLC EPLQRHLATL
160 170 180 190 200
RPLSKEDTFE AVAPFMANGP LTFHPRQAPE GALCQDCVRQ VSRLQEAVRS
210 220 230 240 250
NLTLADLNIQ EQCESLGPGL AVLCKNYLFQ FFVPADQALR LLPPQELCRK
260 270 280 290 300
GGFCEELGAP ARLTQVVAMD GVPSLELGLP RKQSEMQMKA GVTCEVCMNV
310 320 330 340 350
VQKLDHWLMS NSSELMITHA LERVCSVMPA SITKECIILV DTYSPSLVQL
360 370 380 390 400
VAKITPEKVC KFIRLCGNRR RARAVHDAYA IVPSPEWDAE NQGSFCNGCK
410 420 430 440 450
RLLTVSSHNL ESKSTKRDIL VAFKGGCSIL PLPYMIQCKH FVTQYEPVLI
460 470 480 490 500
ESLKDMMDPV AVCKKVGACH GPRTPLLGTD QCALGPSFWC RSQEAAKLCN
510 520
AVQHCQKHVW KEMHLHAGEH A
Length:521
Mass (Da):56,627
Last modified:March 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0E1ED7B942D1ECB2
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH68579 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC05143 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06178041A → S. Corresponds to variant dbSNP:rs11548325Ensembl.1
Natural variantiVAR_06178144G → R. Corresponds to variant dbSNP:rs58482081Ensembl.1
Natural variantiVAR_06178259A → T. Corresponds to variant dbSNP:rs56737582Ensembl.1
Natural variantiVAR_051895268A → S. Corresponds to variant dbSNP:rs3796905Ensembl.1
Natural variantiVAR_051896296V → M. Corresponds to variant dbSNP:rs6850206Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ991252 mRNA Translation: ABJ55983.1
BC068579 mRNA Translation: AAH68579.1 Different initiation.
AK097698 mRNA Translation: BAC05143.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47009.1

NCBI Reference Sequences

More...
RefSeqi
NP_001078851.1, NM_001085382.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000319098; ENSP00000317445; ENSG00000178597

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
768239

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:768239

UCSC genome browser

More...
UCSCi
uc011bwj.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ991252 mRNA Translation: ABJ55983.1
BC068579 mRNA Translation: AAH68579.1 Different initiation.
AK097698 mRNA Translation: BAC05143.1 Sequence problems.
CCDSiCCDS47009.1
RefSeqiNP_001078851.1, NM_001085382.1

3D structure databases

SMRiQ6NUJ1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi612854, 1 interactor
STRINGi9606.ENSP00000317445

PTM databases

GlyGeniQ6NUJ1, 2 sites
iPTMnetiQ6NUJ1
PhosphoSitePlusiQ6NUJ1

Genetic variation databases

BioMutaiPSAPL1
DMDMi134035030

Proteomic databases

MassIVEiQ6NUJ1
MaxQBiQ6NUJ1
PaxDbiQ6NUJ1
PeptideAtlasiQ6NUJ1
PRIDEiQ6NUJ1
ProteomicsDBi66682

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
43373, 92 antibodies

The DNASU plasmid repository

More...
DNASUi
768239

Genome annotation databases

EnsembliENST00000319098; ENSP00000317445; ENSG00000178597
GeneIDi768239
KEGGihsa:768239
UCSCiuc011bwj.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
768239
DisGeNETi768239

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PSAPL1
HGNCiHGNC:33131, PSAPL1
HPAiENSG00000178597, Group enriched (skin, stomach, testis)
neXtProtiNX_Q6NUJ1
OpenTargetsiENSG00000178597
PharmGKBiPA162400215
VEuPathDBiHostDB:ENSG00000178597

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1340, Eukaryota
GeneTreeiENSGT00940000164031
HOGENOMiCLU_033757_0_0_1
InParanoidiQ6NUJ1
OMAiKTCEWLP
OrthoDBi865505at2759
PhylomeDBiQ6NUJ1
TreeFamiTF316942

Enzyme and pathway databases

PathwayCommonsiQ6NUJ1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
768239, 8 hits in 1002 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
768239
PharosiQ6NUJ1, Tdark

Protein Ontology

More...
PROi
PR:Q6NUJ1
RNActiQ6NUJ1, protein

Gene expression databases

BgeeiENSG00000178597, Expressed in mammalian vulva and 87 other tissues
GenevisibleiQ6NUJ1, HS

Family and domain databases

InterProiView protein in InterPro
IPR003119, SAP_A
IPR007856, SapB_1
IPR008138, SapB_2
IPR008373, Saposin
IPR011001, Saposin-like
IPR021165, Saposin_chordata
IPR008139, SaposinB_dom
PfamiView protein in Pfam
PF02199, SapA, 2 hits
PF05184, SapB_1, 1 hit
PF03489, SapB_2, 2 hits
PIRSFiPIRSF002431, Saposin, 1 hit
PRINTSiPR01797, SAPOSIN
SMARTiView protein in SMART
SM00162, SAPA, 2 hits
SM00741, SapB, 4 hits
SUPFAMiSSF47862, SSF47862, 4 hits
PROSITEiView protein in PROSITE
PS51110, SAP_A, 2 hits
PS50015, SAP_B, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSAPL1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NUJ1
Secondary accession number(s): A0A184, Q8N7T4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: September 29, 2021
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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