UniProtKB - Q6NSQ7 (LTV1_MOUSE)
Protein
Protein LTV1 homolog
Gene
Ltv1
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Biological processi
- ribosomal small subunit biogenesis Source: GO_Central
- ribosomal small subunit export from nucleus Source: GO_Central
Enzyme and pathway databases
Reactomei | R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol |
Names & Taxonomyi
Protein namesi | Recommended name: Protein LTV1 homolog |
Gene namesi | Name:Ltv1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2447810, Ltv1 |
Subcellular locationi
Cytosol
- cytosol Source: MGI
Nucleus
- nucleoplasm Source: MGI
- nucleus Source: GO_Central
Other locations
- preribosome, small subunit precursor Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000302814 | 1 – 470 | Protein LTV1 homologAdd BLAST | 470 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 17 | PhosphoserineBy similarity | 1 | |
Modified residuei | 24 | PhosphoserineBy similarity | 1 | |
Modified residuei | 243 | PhosphoserineCombined sources | 1 | |
Modified residuei | 326 | PhosphoserineBy similarity | 1 | |
Modified residuei | 403 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q6NSQ7 |
MaxQBi | Q6NSQ7 |
PaxDbi | Q6NSQ7 |
PeptideAtlasi | Q6NSQ7 |
PRIDEi | Q6NSQ7 |
PTM databases
iPTMneti | Q6NSQ7 |
PhosphoSitePlusi | Q6NSQ7 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000019814, Expressed in forelimb bud and 319 other tissues |
Genevisiblei | Q6NSQ7, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 237279, 1 interactor |
IntActi | Q6NSQ7, 3 interactors |
MINTi | Q6NSQ7 |
STRINGi | 10090.ENSMUSP00000019950 |
Miscellaneous databases
RNActi | Q6NSQ7, protein |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 414 – 470 | Sequence analysisAdd BLAST | 57 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 136 – 198 | Asp-richAdd BLAST | 63 |
Sequence similaritiesi
Belongs to the LTV1 family.Curated
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | KOG2637, Eukaryota |
GeneTreei | ENSGT00390000002789 |
HOGENOMi | CLU_035718_0_0_1 |
InParanoidi | Q6NSQ7 |
OMAi | KKWDCES |
OrthoDBi | 917248at2759 |
PhylomeDBi | Q6NSQ7 |
TreeFami | TF314845 |
Family and domain databases
InterProi | View protein in InterPro IPR007307, Ltv1 |
PANTHERi | PTHR21531, PTHR21531, 1 hit |
Pfami | View protein in Pfam PF04180, LTV, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6NSQ7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPHRKKKPFI EKKKAVSFHL VHRSQRDPLA ADETAPQRVL LPTQKVNDEE
60 70 80 90 100
RRAEQRKYGV FFDDDYDYLQ HLKEPSGPAE LIPSTSFATP LCDKTEDPCV
110 120 130 140 150
YSSTGIKLPS SVFASEFEED VGLLNKAAPV SGPRLDFDPD IVAALDDDFD
160 170 180 190 200
FDDPENLLED DFILQANKPT GGERMDTESE EDDGHEWEDM DDEEGSDDRS
210 220 230 240 250
SAGFLSDGGD LSAPGSPQEA MKKHLFWEEE TKSRFTEYSM TSSVMRRNEQ
260 270 280 290 300
LTLHDERFEK FYEQYDDVEI GALDNAELEG TIQVDSNRLQ EVLNDYYKEK
310 320 330 340 350
AENCVKLSTL EPFEDQDLPT NELDESEKEE TITVVLEEAK EKWDCESICS
360 370 380 390 400
TYSNLYNHPQ LIKYEPKPKQ IHLSSKTGIP LNVLPKKGLT AKQVERMQMI
410 420 430 440 450
NGSDLPKVST QPRSKDETKE DKRARKQAIK EERKERRVEK KANKLAFKLE
460 470
KRRQEKELLN LKKNIEGLKL
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 86 | S → T in AAH69962 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 185 | H → N in AAH69962 (PubMed:15489334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK011491 mRNA Translation: BAB27653.1 BC067062 mRNA Translation: AAH67062.1 BC069962 mRNA Translation: AAH69962.1 |
CCDSi | CCDS35845.1 |
RefSeqi | NP_852135.1, NM_181470.4 |
Genome annotation databases
Ensembli | ENSMUST00000019950; ENSMUSP00000019950; ENSMUSG00000019814 |
GeneIDi | 353258 |
KEGGi | mmu:353258 |
UCSCi | uc007ekp.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK011491 mRNA Translation: BAB27653.1 BC067062 mRNA Translation: AAH67062.1 BC069962 mRNA Translation: AAH69962.1 |
CCDSi | CCDS35845.1 |
RefSeqi | NP_852135.1, NM_181470.4 |
3D structure databases
SMRi | Q6NSQ7 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 237279, 1 interactor |
IntActi | Q6NSQ7, 3 interactors |
MINTi | Q6NSQ7 |
STRINGi | 10090.ENSMUSP00000019950 |
PTM databases
iPTMneti | Q6NSQ7 |
PhosphoSitePlusi | Q6NSQ7 |
Proteomic databases
EPDi | Q6NSQ7 |
MaxQBi | Q6NSQ7 |
PaxDbi | Q6NSQ7 |
PeptideAtlasi | Q6NSQ7 |
PRIDEi | Q6NSQ7 |
Genome annotation databases
Ensembli | ENSMUST00000019950; ENSMUSP00000019950; ENSMUSG00000019814 |
GeneIDi | 353258 |
KEGGi | mmu:353258 |
UCSCi | uc007ekp.1, mouse |
Organism-specific databases
CTDi | 84946 |
MGIi | MGI:2447810, Ltv1 |
Phylogenomic databases
eggNOGi | KOG2637, Eukaryota |
GeneTreei | ENSGT00390000002789 |
HOGENOMi | CLU_035718_0_0_1 |
InParanoidi | Q6NSQ7 |
OMAi | KKWDCES |
OrthoDBi | 917248at2759 |
PhylomeDBi | Q6NSQ7 |
TreeFami | TF314845 |
Enzyme and pathway databases
Reactomei | R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol |
Miscellaneous databases
BioGRID-ORCSi | 353258, 8 hits in 18 CRISPR screens |
PROi | PR:Q6NSQ7 |
RNActi | Q6NSQ7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000019814, Expressed in forelimb bud and 319 other tissues |
Genevisiblei | Q6NSQ7, MM |
Family and domain databases
InterProi | View protein in InterPro IPR007307, Ltv1 |
PANTHERi | PTHR21531, PTHR21531, 1 hit |
Pfami | View protein in Pfam PF04180, LTV, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LTV1_MOUSE | |
Accessioni | Q6NSQ7Primary (citable) accession number: Q6NSQ7 Secondary accession number(s): Q9D0F5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 11, 2007 |
Last sequence update: | September 11, 2007 | |
Last modified: | December 2, 2020 | |
This is version 97 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families