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Entry version 126 (26 Feb 2020)
Sequence version 3 (02 Nov 2010)
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Protein

Pleckstrin homology-like domain family B member 3

Gene

PHLDB3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pleckstrin homology-like domain family B member 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PHLDB3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30499 PHLDB3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6NSJ2

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000176531

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6NSJ2 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PHLDB3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033417

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000538961 – 640Pleckstrin homology-like domain family B member 3Add BLAST640

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6NSJ2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6NSJ2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6NSJ2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6NSJ2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6NSJ2

PeptideAtlas

More...
PeptideAtlasi
Q6NSJ2

PRoteomics IDEntifications database

More...
PRIDEi
Q6NSJ2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66637 [Q6NSJ2-1]
66638 [Q6NSJ2-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6NSJ2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6NSJ2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000176531 Expressed in lower esophagus mucosa and 129 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6NSJ2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6NSJ2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043425

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
575902, 65 interactors

Protein interaction database and analysis system

More...
IntActi
Q6NSJ2, 23 interactors

Molecular INTeraction database

More...
MINTi
Q6NSJ2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000292140

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6NSJ2 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6NSJ2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini532 – 635PHPROSITE-ProRule annotationAdd BLAST104

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili104 – 327Sequence analysisAdd BLAST224
Coiled coili454 – 481Sequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PH domain mediates the binding to phosphoinositides.By similarity

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE1E Eukaryota
ENOG410YDTB LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160803

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_028602_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6NSJ2

KEGG Orthology (KO)

More...
KOi
K23794

Identification of Orthologs from Complete Genome Data

More...
OMAi
PESCPHL

Database of Orthologous Groups

More...
OrthoDBi
70229at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6NSJ2

TreeFam database of animal gene trees

More...
TreeFami
TF338037

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14673 PH_PHLDB1_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR037810 PHLDB1/2/3_PH

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00169 PH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00233 PH, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50003 PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6NSJ2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGTRSSPEEG TPPPLVPECD VEVQPQGHPE ESREQEASEV LAEPSSRGGA
60 70 80 90 100
EQQAEEEEVG EGSSTESSRD APEATPPIAM AATPPASTSS REGVRGAARR
110 120 130 140 150
LQGQQLEALT RVALMEQRVK ELQRQRKELR IEMEVEVALL RGELAGERVA
160 170 180 190 200
ARREEEQLRE LLEQQAASEQ RGRQQREQEQ RRLSQERDRL EGLRQRLRKA
210 220 230 240 250
QGQLDSQPED QRERLLQGVQ EMREQLDVAQ RAYEDLEFQQ LERESRQEEE
260 270 280 290 300
DRDSPGPQVP DPKVQELQAS MAQHRRGALQ HRIRVLEEQL KSLGEQMAAE
310 320 330 340 350
SRGLSRKKEE ALQALSQERS RLLELNCLQG TPGGDFSEPN PALTKLLFTQ
360 370 380 390 400
KTDRQLLVLQ DAVAHSAATP TSSCLFSVHS SLQGSIGLQR TGSLPRKRGE
410 420 430 440 450
RGSQRGSPRP LSFHCTESLE ASALPPAVGD SGRYPLYQLL NCGRGNSCGA
460 470 480 490 500
IHPDIAHMER LLQQAMAERE RLLKAREGTR RGTEGSSGPA VPAITAPPTP
510 520 530 540 550
PHPPGPRILD LRQHLEGWGH NPENCPHVQV SGCCCRGPLV KMGGRIKTWR
560 570 580 590 600
KRWFCFDRQA RRLAYYADKE ETKLKGVIYF QAIEEVYYDH LRCAFKSPNP
610 620 630 640
RLTFCVKTYE RLFYMVAPSP EAMRIWMDVI VTAADENHAP
Length:640
Mass (Da):71,912
Last modified:November 2, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA752825E3FFBFEDE
GO
Isoform 2 (identifier: Q6NSJ2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     276-279: RGAL → VSHA
     280-640: Missing.

Show »
Length:279
Mass (Da):31,642
Checksum:iC4222E0A2492FE1C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R353M0R353_HUMAN
Pleckstrin homology-like domain fam...
PHLDB3
232Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R3I7M0R3I7_HUMAN
Pleckstrin homology-like domain fam...
PHLDB3
110Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QXT7M0QXT7_HUMAN
Pleckstrin homology-like domain fam...
PHLDB3
122Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R038M0R038_HUMAN
Pleckstrin homology-like domain fam...
PHLDB3
101Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC05082 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_056671239Q → R1 PublicationCorresponds to variant dbSNP:rs11083711Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_039923276 – 279RGAL → VSHA in isoform 2. 2 Publications4
Alternative sequenceiVSP_039924280 – 640Missing in isoform 2. 2 PublicationsAdd BLAST361

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK097512 mRNA Translation: BAC05082.1 Sequence problems.
AC018758 Genomic DNA No translation available.
BC070094 mRNA Translation: AAH70094.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12621.2 [Q6NSJ2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_942147.3, NM_198850.3 [Q6NSJ2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000292140; ENSP00000292140; ENSG00000176531 [Q6NSJ2-1]
ENST00000599242; ENSP00000471158; ENSG00000176531 [Q6NSJ2-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
653583

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:653583

UCSC genome browser

More...
UCSCi
uc002own.5 human [Q6NSJ2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097512 mRNA Translation: BAC05082.1 Sequence problems.
AC018758 Genomic DNA No translation available.
BC070094 mRNA Translation: AAH70094.1
CCDSiCCDS12621.2 [Q6NSJ2-1]
RefSeqiNP_942147.3, NM_198850.3 [Q6NSJ2-1]

3D structure databases

SMRiQ6NSJ2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi575902, 65 interactors
IntActiQ6NSJ2, 23 interactors
MINTiQ6NSJ2
STRINGi9606.ENSP00000292140

PTM databases

iPTMnetiQ6NSJ2
PhosphoSitePlusiQ6NSJ2

Polymorphism and mutation databases

BioMutaiPHLDB3
DMDMi311033417

Proteomic databases

EPDiQ6NSJ2
jPOSTiQ6NSJ2
MassIVEiQ6NSJ2
MaxQBiQ6NSJ2
PaxDbiQ6NSJ2
PeptideAtlasiQ6NSJ2
PRIDEiQ6NSJ2
ProteomicsDBi66637 [Q6NSJ2-1]
66638 [Q6NSJ2-2]

Genome annotation databases

EnsembliENST00000292140; ENSP00000292140; ENSG00000176531 [Q6NSJ2-1]
ENST00000599242; ENSP00000471158; ENSG00000176531 [Q6NSJ2-2]
GeneIDi653583
KEGGihsa:653583
UCSCiuc002own.5 human [Q6NSJ2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
653583

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PHLDB3
HGNCiHGNC:30499 PHLDB3
HPAiHPA043425
neXtProtiNX_Q6NSJ2
OpenTargetsiENSG00000176531

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE1E Eukaryota
ENOG410YDTB LUCA
GeneTreeiENSGT00940000160803
HOGENOMiCLU_028602_0_0_1
InParanoidiQ6NSJ2
KOiK23794
OMAiPESCPHL
OrthoDBi70229at2759
PhylomeDBiQ6NSJ2
TreeFamiTF338037

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PHLDB3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
653583
PharosiQ6NSJ2 Tdark

Protein Ontology

More...
PROi
PR:Q6NSJ2
RNActiQ6NSJ2 protein

Gene expression databases

BgeeiENSG00000176531 Expressed in lower esophagus mucosa and 129 other tissues
ExpressionAtlasiQ6NSJ2 baseline and differential
GenevisibleiQ6NSJ2 HS

Family and domain databases

CDDicd14673 PH_PHLDB1_2, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR037810 PHLDB1/2/3_PH
PfamiView protein in Pfam
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPHLB3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NSJ2
Secondary accession number(s): Q8N7Z4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: November 2, 2010
Last modified: February 26, 2020
This is version 126 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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