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Entry version 126 (16 Oct 2019)
Sequence version 2 (03 Mar 2009)
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Protein

Protein RRP5 homolog

Gene

Pdcd11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processrRNA processing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein RRP5 homolog
Alternative name(s):
Apoptosis-linked gene 4 protein
Programmed cell death protein 11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pdcd11
Synonyms:Alg4, Kiaa0185
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1341788 Pdcd11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003642002 – 1862Protein RRP5 homologAdd BLAST1861

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei7PhosphoserineBy similarity1
Modified residuei438PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki1424Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1468PhosphoserineCombined sources1
Modified residuei1490PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6NS46

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q6NS46

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6NS46

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6NS46

PeptideAtlas

More...
PeptideAtlasi
Q6NS46

PRoteomics IDEntifications database

More...
PRIDEi
Q6NS46

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6NS46

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6NS46

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q6NS46

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000025047 Expressed in 240 organ(s), highest expression level in blastocyst

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q6NS46 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with NF-kappa-B p50/NFKB1 and NF-kappa-B p65/RELA.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
202073, 4 interactors

Protein interaction database and analysis system

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IntActi
Q6NS46, 1 interactor

Molecular INTeraction database

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MINTi
Q6NS46

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000072008

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6NS46

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini83 – 171S1 motif 1PROSITE-ProRule annotationAdd BLAST89
Domaini187 – 258S1 motif 2PROSITE-ProRule annotationAdd BLAST72
Domaini281 – 346S1 motif 3PROSITE-ProRule annotationAdd BLAST66
Domaini365 – 436S1 motif 4PROSITE-ProRule annotationAdd BLAST72
Domaini453 – 522S1 motif 5PROSITE-ProRule annotationAdd BLAST70
Domaini542 – 611S1 motif 6PROSITE-ProRule annotationAdd BLAST70
Domaini636 – 707S1 motif 7PROSITE-ProRule annotationAdd BLAST72
Domaini729 – 798S1 motif 8PROSITE-ProRule annotationAdd BLAST70
Domaini846 – 911S1 motif 9PROSITE-ProRule annotationAdd BLAST66
Domaini1047 – 1120S1 motif 10PROSITE-ProRule annotationAdd BLAST74
Domaini1160 – 1233S1 motif 11PROSITE-ProRule annotationAdd BLAST74
Domaini1241 – 1309S1 motif 12PROSITE-ProRule annotationAdd BLAST69
Domaini1335 – 1407S1 motif 13PROSITE-ProRule annotationAdd BLAST73
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1590 – 1622HAT 1Add BLAST33
Repeati1696 – 1728HAT 2Add BLAST33
Repeati1766 – 1798HAT 3Add BLAST33
Repeati1800 – 1835HAT 4Add BLAST36

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1070 Eukaryota
COG0539 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012228

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q6NS46

KEGG Orthology (KO)

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KOi
K14792

Identification of Orthologs from Complete Genome Data

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OMAi
GQYLRAY

Database of Orthologous Groups

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OrthoDBi
23482at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q6NS46

TreeFam database of animal gene trees

More...
TreeFami
TF105697

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR003107 HAT
IPR012340 NA-bd_OB-fold
IPR022967 S1_dom
IPR003029 S1_domain
IPR008847 Suf
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00575 S1, 4 hits
PF05843 Suf, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00386 HAT, 7 hits
SM00316 S1, 13 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 2 hits
SSF50249 SSF50249, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50126 S1, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q6NS46-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANLEESFPR GGTRKLHKSE KSSQQVVEQD NLFDVSTEEG PIKRKKSQKG
60 70 80 90 100
PAKTKKLKIE KRKSIKSIKE KFEILSLESL CEGMRILGCV KEVSELELVV
110 120 130 140 150
SLPNGLQGFV QVTEVCDAYT QKLNEQVAQE EPLEDLLRLP ELFSPGMLVR
160 170 180 190 200
CVVSSLDVTE SGKKSVKLSV NPKRVNKVLS ADALRPGMLL TGTVSSLEDH
210 220 230 240 250
GYLVDIGVGG TRAFLSLKKA QEYIRQKNKG AKFKVGQYLT CVVEEVKSNG
260 270 280 290 300
GVVSLSVEHS EVSSAFATEE QSWNLNNLLP GLLVKAQVQK VTQFGLQLNF
310 320 330 340 350
LTFFKGLVDF MHLEPKKMGS YSSNQTVKAC ILCVHPRTRV VRLSLRPIFL
360 370 380 390 400
HPGRPLTRIS YQQLGAVLDD VPVQGFFKNA GAIFRLKDGV LAYARVSHLS
410 420 430 440 450
DSKKAFNAEA FKPGSTHKCR IIDYSQMDEL ALLSLRKSII AAPFLRYHDI
460 470 480 490 500
KIGTVVKGTV LAIKPFGILV KVGEQIKGLV PSMHLADIMM KNPEKKYSPG
510 520 530 540 550
DEVKCRVLLC DPEAKKLIMT LKKTLVTSKL SLITCYEGAK PGLQTHGVII
560 570 580 590 600
RVKDYGCIVK FYNDVQGLVP KHELSTQHIP DPETVFYTGQ VVKVAVLSCE
610 620 630 640 650
PSKERMLLSF RLLSDSRPKD PGVESSQKKT GAVRIGQLVD VKVLEKTKTG
660 670 680 690 700
LEVAILPHNT PAFLPTPHLS DHAANGPLLH HWLQTGDTLH RVLCLSQSER
710 720 730 740 750
HILLCRKPAL VSTVEGGQDP KSLSEIQPGM LLIGFVKCIK EYGVFVQFPS
760 770 780 790 800
GLSGLSPKTI MSDKFVTTPS EHFVEGQTVV AKVTNVDESK QRMLLSLRLS
810 820 830 840 850
DCSLGDSAST SFLLLCQCLE ELQGIRSLMS NQDSVLIQTL ADMTPGMVLD
860 870 880 890 900
AVVHEVLEDG SVVFSSDPVP DLVLRASRYH RAGQEVEPGQ KKKVVVLHVD
910 920 930 940 950
MLKLEVHVSL HQDLVNRKTR KLRKSSRHQG IVQHLEESFA VASLVETGHL
960 970 980 990 1000
VAFSLISHLN DTFHFDSEKL RVGQGVCLTL KTTEPGVTGL ILAVEGPASK
1010 1020 1030 1040 1050
RTRMPVQRDS ETVDDKGEEK EEEEEEEEKE EENLTVKSKK RHSLAIGDKV
1060 1070 1080 1090 1100
TGTIKAVKAT HVVVTLADGF VGCIHASRIL DDVPVGTSPT TTLKAGKKVT
1110 1120 1130 1140 1150
ARVIGGRDVK TSKFLPISHP RFVLTILELS VRPSELKGSY SALNTHSESP
1160 1170 1180 1190 1200
VEKIRQYQAG QTVTCFFKKY NVMKKWLEVD IGPDIRGRIP LLLTSLSFKV
1210 1220 1230 1240 1250
LKHPDKKFQV GQAIEATVVD PDVPRAFLCL SLIGPYRLEE GEVAMGRVMK
1260 1270 1280 1290 1300
VVPNRGLTVS FPFGKIGKVS MFHLSDSYSE APLEDFCPQK IVRCYILSTA
1310 1320 1330 1340 1350
HRVLALSLRS SRTNRETKNR IEDPEINSIE DVKEGQLLRG YVKCVLPSSV
1360 1370 1380 1390 1400
IIGLGPSVLG LAKYSHVSEC VPPEKELYNG CLPEGKLVTA KVLRVNPMKN
1410 1420 1430 1440 1450
LIELSLLPSD TGRPDVFSPA PEPKQEERSG GAEEGQKRKE KNQKRREEKE
1460 1470 1480 1490 1500
EPQKSQRGGR GKRERQESES EQELVNKRPK KSGAAEEDDS GVEVYYREGE
1510 1520 1530 1540 1550
DEVGEPKLPP RGKQTKSTEV PRLHLSSGFL WDVGLDSLTP ALPLREESSD
1560 1570 1580 1590 1600
SEDEQPHQAK KKKGKKEREL EKQKAEKELS RIEEALMDPG RQPESADDFD
1610 1620 1630 1640 1650
RLVLSSPNSS ILWLQYMAFH LQATEIEKAR AVAERALKTI SFREEQEKLN
1660 1670 1680 1690 1700
VWVALLNLEN MYGSQESLTK VFERAVQYNE PLKVFLHLAD IYTKSEKYKE
1710 1720 1730 1740 1750
AGELYNRMLK RFRQEKAVWI KYGAFVLGRS QAGASHRVLQ RALECLPAKE
1760 1770 1780 1790 1800
HVDVIVKFAQ LEFQLGDVER AKAIFENTLS TYPKRTDVWS VYIDMTIKHG
1810 1820 1830 1840 1850
SQTAVRDIFE RVIHLSLAPK RMKFFFKRYL DYEKQHGTEK DVQAVKAKAL
1860
EYVEAKSSAL ED
Length:1,862
Mass (Da):207,779
Last modified:March 3, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF2045A86EE8C9626
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD20941 differs from that shown. The mRNA 5'- and 3'-ends do not match to the genomic DNA.Curated
The sequence BAB23064 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAC97890 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti38E → A in BAE28246 (PubMed:16141072).Curated1
Sequence conflicti187G → D in BAE28246 (PubMed:16141072).Curated1
Sequence conflicti531S → P in BAC97890 (PubMed:14621295).Curated1
Sequence conflicti919T → P in BAC97890 (PubMed:14621295).Curated1
Sequence conflicti1027 – 1028Missing in BAC97890 (PubMed:14621295).Curated2
Sequence conflicti1337L → H in BAE28246 (PubMed:16141072).Curated1
Sequence conflicti1469 – 1471ESE → TRP in AAH38503 (PubMed:15489334).Curated3
Sequence conflicti1519E → Q in AAH38503 (PubMed:15489334).Curated1
Sequence conflicti1556P → L in BAC97890 (PubMed:14621295).Curated1
Sequence conflicti1556P → L in AAH38503 (PubMed:15489334).Curated1
Sequence conflicti1851E → D in AAH70468 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK129080 mRNA Translation: BAC97890.1 Different initiation.
BC038503 mRNA Translation: AAH38503.1
BC055276 mRNA Translation: AAH55276.3
BC070468 mRNA Translation: AAH70468.1
AK003899 mRNA Translation: BAB23064.2 Different initiation.
AK141450 mRNA Translation: BAE24688.1
AK147950 mRNA Translation: BAE28246.1
AK161803 mRNA Translation: BAE36581.1
AF055668 mRNA Translation: AAD20941.1 Sequence problems.
AF055669 mRNA Translation: AAD20942.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS29888.1

NCBI Reference Sequences

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RefSeqi
NP_035183.2, NM_011053.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000072141; ENSMUSP00000072008; ENSMUSG00000025047

Database of genes from NCBI RefSeq genomes

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GeneIDi
18572

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:18572

UCSC genome browser

More...
UCSCi
uc008hup.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129080 mRNA Translation: BAC97890.1 Different initiation.
BC038503 mRNA Translation: AAH38503.1
BC055276 mRNA Translation: AAH55276.3
BC070468 mRNA Translation: AAH70468.1
AK003899 mRNA Translation: BAB23064.2 Different initiation.
AK141450 mRNA Translation: BAE24688.1
AK147950 mRNA Translation: BAE28246.1
AK161803 mRNA Translation: BAE36581.1
AF055668 mRNA Translation: AAD20941.1 Sequence problems.
AF055669 mRNA Translation: AAD20942.1
CCDSiCCDS29888.1
RefSeqiNP_035183.2, NM_011053.2

3D structure databases

SMRiQ6NS46
ModBaseiSearch...

Protein-protein interaction databases

BioGridi202073, 4 interactors
IntActiQ6NS46, 1 interactor
MINTiQ6NS46
STRINGi10090.ENSMUSP00000072008

PTM databases

iPTMnetiQ6NS46
PhosphoSitePlusiQ6NS46
SwissPalmiQ6NS46

Proteomic databases

EPDiQ6NS46
jPOSTiQ6NS46
MaxQBiQ6NS46
PaxDbiQ6NS46
PeptideAtlasiQ6NS46
PRIDEiQ6NS46

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
18572

Genome annotation databases

EnsembliENSMUST00000072141; ENSMUSP00000072008; ENSMUSG00000025047
GeneIDi18572
KEGGimmu:18572
UCSCiuc008hup.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
22984
MGIiMGI:1341788 Pdcd11

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG1070 Eukaryota
COG0539 LUCA
GeneTreeiENSGT00390000012228
InParanoidiQ6NS46
KOiK14792
OMAiGQYLRAY
OrthoDBi23482at2759
PhylomeDBiQ6NS46
TreeFamiTF105697

Enzyme and pathway databases

ReactomeiR-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Pdcd11 mouse

Protein Ontology

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PROi
PR:Q6NS46

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000025047 Expressed in 240 organ(s), highest expression level in blastocyst
GenevisibleiQ6NS46 MM

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR003107 HAT
IPR012340 NA-bd_OB-fold
IPR022967 S1_dom
IPR003029 S1_domain
IPR008847 Suf
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF00575 S1, 4 hits
PF05843 Suf, 1 hit
SMARTiView protein in SMART
SM00386 HAT, 7 hits
SM00316 S1, 13 hits
SUPFAMiSSF48452 SSF48452, 2 hits
SSF50249 SSF50249, 11 hits
PROSITEiView protein in PROSITE
PS50126 S1, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRRP5_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NS46
Secondary accession number(s): Q3TSU4
, Q3UGG2, Q3URK0, Q6PIA8, Q6ZQH2, Q7TPE2, Q9CTD8, Q9R1Z2, Q9WTU7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 16, 2019
This is version 126 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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