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Protein

Calmodulin-binding transcription activator 2

Gene

CAMTA2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity). Regulates transcriptional activity in response to calcium signals (Probable). Binds calmodulin in a calcium-dependent manner (By similarity). Involved in freezing tolerance in association with CAMTA1 and CAMTA3. Contributes together with CAMTA1 and CAMTA3 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:23581962). Involved together with CAMTA3 and CAMTA4 in the positive regulation of a general stress response (PubMed:25039701). Involved in tolerance to aluminum. Binds to the promoter of ALMT1 transporter and contributes to the positive regulation of aluminum-induced expression of ALMT1 (PubMed:25627216).By similarity1 Publication3 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi15 – 141CG-1PROSITE-ProRule annotationAdd BLAST127

GO - Molecular functioni

GO - Biological processi

  • cellular response to aluminum ion Source: TAIR
  • positive regulation of transcription, DNA-templated Source: TAIR
  • positive regulation of transcription by RNA polymerase II Source: GO_Central
  • regulation of transcription, DNA-templated Source: TAIR
  • response to cold Source: TAIR

Keywordsi

Molecular functionActivator, Calmodulin-binding, DNA-binding
Biological processStress response, Transcription, Transcription regulation
LigandCalcium

Names & Taxonomyi

Protein namesi
Recommended name:
Calmodulin-binding transcription activator 21 Publication
Short name:
AtCAMTA21 Publication
Alternative name(s):
AtER661 Publication
Ethylene-induced calmodulin-binding protein c1 Publication
Short name:
EICBP.c1 Publication
Signal-responsive protein 41 Publication
Short name:
AtSR41 Publication
Gene namesi
Name:CAMTA21 Publication
Synonyms:CMTA2Curated, SR41 Publication
Ordered Locus Names:At5g64220Imported
ORF Names:MSJ1.6Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G64220
TAIRilocus:2173368 AT5G64220

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

No visible phenotype under normal growth conditions, but the double mutants camt2 and camt3 exhibit dwarf phenotypes.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001144871 – 1050Calmodulin-binding transcription activator 2Add BLAST1050

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei984PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6NPP4
PRIDEiQ6NPP4

PTM databases

iPTMnetiQ6NPP4

Expressioni

Tissue specificityi

Expressed in roots, stems, old leaves, petals, sepals, top of carpels, stigmas, stamen filaments, anthers and siliques, but not in pollen.2 Publications

Inductioni

By salt, wounding, abscisic acid, H2O2 and salicylic acid (PubMed:12218065). Induced by aluminum (PubMed:25627216).2 Publications

Gene expression databases

ExpressionAtlasiQ6NPP4 baseline and differential
GenevisibleiQ6NPP4 AT

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi3702.AT5G64220.1

Structurei

3D structure databases

ProteinModelPortaliQ6NPP4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati661 – 690ANK 1Add BLAST30
Repeati694 – 723ANK 2Add BLAST30
Domaini870 – 899IQ 1PROSITE-ProRule annotationAdd BLAST30
Domaini893 – 922IQ 2PROSITE-ProRule annotationAdd BLAST30

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni918 – 940Calmodulin-bindingBy similarityAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili957 – 985Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1011 – 1014Poly-Ser4

Sequence similaritiesi

Belongs to the CAMTA family.Curated

Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG0520 Eukaryota
ENOG410XS5M LUCA
HOGENOMiHOG000240102
InParanoidiQ6NPP4
KOiK21596
OMAiAFSGRED
OrthoDBiEOG093600YW
PhylomeDBiQ6NPP4

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR005559 CG-1_dom
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR000048 IQ_motif_EF-hand-BS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF03859 CG-1, 1 hit
PF00612 IQ, 2 hits
SMARTiView protein in SMART
SM00248 ANK, 2 hits
SM01076 CG-1, 1 hit
SM00015 IQ, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF52540 SSF52540, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits
PS51437 CG_1, 1 hit
PS50096 IQ, 2 hits

Sequencei

Sequence statusi: Complete.

Q6NPP4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADRGSFGFA PRLDIKQLLS EAQHRWLRPA EICEILRNHQ KFHIASEPPN
60 70 80 90 100
RPPSGSLFLF DRKVLRYFRK DGHNWRKKKD GKTVKEAHEK LKVGSIDVLH
110 120 130 140 150
CYYAHGEDNE NFQRRCYWML EQDLMHIVFV HYLEVKGNRM STSGTKENHS
160 170 180 190 200
NSLSGTGSVN VDSTATRSSI LSPLCEDADS GDSRQASSSL QQNPEPQTVV
210 220 230 240 250
PQIMHHQNAS TINSYNTTSV LGNRDGWTSA HGNRVKGSNS QRSGDVPAWD
260 270 280 290 300
ASFENSLARY QNLPYNAPLT QTQPSTFGLI PMEGKTEKGS LLTSEHLRNP
310 320 330 340 350
LQSQVNWQTP VQESVPLQKW PMDSHSGMTD ATDLALFGQG AHENFGTFSS
360 370 380 390 400
LLGSQDQQSS SFQAPFTNNE AAYIPKLGPE DLIYEASANQ TLPLRKALLK
410 420 430 440 450
KEDSLKKVDS FSRWVSKELG EMEDLQMQSS SGGIAWTSVE CENAAAGSSL
460 470 480 490 500
SPSLSEDQRF TMIDFWPKWT QTDSEVEVMV IGTFLLSPQE VTSYSWSCMF
510 520 530 540 550
GEVEVPADIL VDGVLCCHAP PHEVGRVPFY ITCSDRFSCS EVREFDFLPG
560 570 580 590 600
STRKLNATDI YGANTIETSL HLRFENLLAL RCSVQEHHIF ENVGEKRRKI
610 620 630 640 650
SKIMLLKDEK EPPLPGTIEK DLTELEAKER LIREEFEDKL YLWLIHKVTE
660 670 680 690 700
EGKGPNILDE DGQGVLHLAA ALGYDWAIKP ILAAGVSINF RDANGWSALH
710 720 730 740 750
WAAFSGREDT VAVLVSLGAD AGALADPSPE HPLGKTAADL AYGNGHRGIS
760 770 780 790 800
GFLAESSLTS YLEKLTVDAK ENSSADSSGA KAVLTVAERT ATPMSYGDVP
810 820 830 840 850
ETLSMKDSLT AVLNATQAAD RLHQVFRMQS FQRKQLSELG GDNKFDISDE
860 870 880 890 900
LAVSFAAAKT KKSGHSSGAV HAAAVQIQKK YRGWKKRKEF LLIRQRIVKI
910 920 930 940 950
QAHVRGHQVR KQYRAIIWSV GLLEKIILRW RRKGSGLRGF KRDTISKPTE
960 970 980 990 1000
PVCPAPQEDD YDFLKEGRKQ TEERLQKALT RVKSMAQYPE ARAQYRRLLT
1010 1020 1030 1040 1050
VVEGFRENEA SSSSALKNNT EEAANYNEED DLIDIDSLLD DDTFMSLAFE
Length:1,050
Mass (Da):117,258
Last modified:July 5, 2004 - v1
Checksum:i318050B641D646F9
GO

Sequence cautioni

The sequence BAB09853 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB008268 Genomic DNA Translation: BAB09853.1 Sequence problems.
CP002688 Genomic DNA Translation: AED97856.1
CP002688 Genomic DNA Translation: AED97857.1
BT010874 mRNA Translation: AAR24652.1
AK229403 mRNA Translation: BAF01265.1
AB493811 mRNA Translation: BAH30649.1
RefSeqiNP_001032135.1, NM_001037058.2
NP_201227.3, NM_125818.3
UniGeneiAt.28963
At.67020

Genome annotation databases

EnsemblPlantsiAT5G64220.1; AT5G64220.1; AT5G64220
AT5G64220.2; AT5G64220.2; AT5G64220
GeneIDi836543
GrameneiAT5G64220.1; AT5G64220.1; AT5G64220
AT5G64220.2; AT5G64220.2; AT5G64220
KEGGiath:AT5G64220

Similar proteinsi

Entry informationi

Entry nameiCMTA2_ARATH
AccessioniPrimary (citable) accession number: Q6NPP4
Secondary accession number(s): Q0WNN4, Q9FMG3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: July 5, 2004
Last modified: September 12, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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