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Entry version 96 (23 Feb 2022)
Sequence version 1 (05 Jul 2004)
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Protein

Protein ABIL3

Gene

ABIL3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein ABIL3
Alternative name(s):
Abl interactor-like protein 3
Short name:
AtABIL3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABIL3
Ordered Locus Names:At5g24310
ORF Names:MOP9.13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G24310

The Arabidopsis Information Resource

More...
TAIRi
locus:2169759, AT5G24310

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001917961 – 321Protein ABIL3Add BLAST321

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6NMC6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
245085 [Q6NMC6-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6NMC6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6NMC6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6NMC6, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds SCAR.

By similarity

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q6NMC6, 3 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT5G24310.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6NMC6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni179 – 273DisorderedSequence analysisAdd BLAST95
Regioni279 – 298DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi195 – 215Polar residuesSequence analysisAdd BLAST21
Compositional biasi239 – 259Polar residuesSequence analysisAdd BLAST21
Compositional biasi279 – 294Basic and acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ABI family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R3IQ, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_054853_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6NMC6

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6NMC6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028457, ABI

The PANTHER Classification System

More...
PANTHERi
PTHR10460, PTHR10460, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 1 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6NMC6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSAAATMPMP REASNYDEIS MQQSMLFSDS LKDLKNLRTQ LYSAAEYFEL
60 70 80 90 100
SYTNDEQKQI VVETLKDYAI KALVNTVDHL GSVTYKVNDF VDEKVDEVAG
110 120 130 140 150
TELRVSCIEQ RLRMCQEYMD HEGRSQQSLV IDTPKFHKRY FLPSGEIKRG
160 170 180 190 200
GNLAKLKNVE GSFDGEDDWN QFRNAVRATI RETPPPPVRK PILQSPSQRK
210 220 230 240 250
PQRSATFSFS SIATAPKKEQ DKRAVSPHRF PLLRSGSVAI RPSSISRPTT
260 270 280 290 300
PSKSRAVTPT PKRYPSEPRR SASVRVAFEK EAQKEPEHQQ QPSKSKRLLK
310 320
ALLSRRKTKK DDTLYTYLDE Y
Length:321
Mass (Da):36,681
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i46452BE2FB967E93
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8BBP2A0A1P8BBP2_ARATH
ABL interactor-like protein 3
ABIL3 ABL interactor-like protein 3, MOP9.13, MOP9_13, At5g24310
307Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8BBP1A0A1P8BBP1_ARATH
ABL interactor-like protein 3
ABIL3 ABL interactor-like protein 3, MOP9.13, MOP9_13, At5g24310
315Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F4KFT1F4KFT1_ARATH
ABL interactor-like protein 3
ABIL3 ABL interactor-like protein 3, MOP9.13, MOP9_13, At5g24310
234Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB10397 differs from that shown. Reason: Erroneous gene model prediction.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti135K → N in strain: cv. Ita-0. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY817014 mRNA Translation: AAW49258.1
AB006701 Genomic DNA Translation: BAB10397.1 Sequence problems.
CP002688 Genomic DNA Translation: AED93285.1
BT011734 mRNA Translation: AAS49097.1
AK222217 mRNA Translation: BAD95383.1
DQ132115 Genomic DNA Translation: AAZ74720.1
DQ132116 Genomic DNA Translation: AAZ74721.1
DQ132117 Genomic DNA Translation: AAZ74722.1
DQ132118 Genomic DNA Translation: AAZ74723.1
DQ132119 Genomic DNA Translation: AAZ74724.1
DQ132120 Genomic DNA Translation: AAZ74725.1
DQ132121 Genomic DNA Translation: AAZ74726.1
DQ132122 Genomic DNA Translation: AAZ74727.1
DQ132123 Genomic DNA Translation: AAZ74728.1
DQ132124 Genomic DNA Translation: AAZ74729.1
DQ132125 Genomic DNA Translation: AAZ74730.1
DQ132126 Genomic DNA Translation: AAZ74731.1
DQ132127 Genomic DNA Translation: AAZ74732.1
DQ132128 Genomic DNA Translation: AAZ74733.1
DQ132129 Genomic DNA Translation: AAZ74734.1
DQ132113 Genomic DNA Translation: AAZ74718.1
DQ132114 Genomic DNA Translation: AAZ74719.1

NCBI Reference Sequences

More...
RefSeqi
NP_197819.2, NM_122337.5 [Q6NMC6-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G24310.1; AT5G24310.1; AT5G24310 [Q6NMC6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
832498

Gramene; a comparative resource for plants

More...
Gramenei
AT5G24310.1; AT5G24310.1; AT5G24310 [Q6NMC6-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G24310

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY817014 mRNA Translation: AAW49258.1
AB006701 Genomic DNA Translation: BAB10397.1 Sequence problems.
CP002688 Genomic DNA Translation: AED93285.1
BT011734 mRNA Translation: AAS49097.1
AK222217 mRNA Translation: BAD95383.1
DQ132115 Genomic DNA Translation: AAZ74720.1
DQ132116 Genomic DNA Translation: AAZ74721.1
DQ132117 Genomic DNA Translation: AAZ74722.1
DQ132118 Genomic DNA Translation: AAZ74723.1
DQ132119 Genomic DNA Translation: AAZ74724.1
DQ132120 Genomic DNA Translation: AAZ74725.1
DQ132121 Genomic DNA Translation: AAZ74726.1
DQ132122 Genomic DNA Translation: AAZ74727.1
DQ132123 Genomic DNA Translation: AAZ74728.1
DQ132124 Genomic DNA Translation: AAZ74729.1
DQ132125 Genomic DNA Translation: AAZ74730.1
DQ132126 Genomic DNA Translation: AAZ74731.1
DQ132127 Genomic DNA Translation: AAZ74732.1
DQ132128 Genomic DNA Translation: AAZ74733.1
DQ132129 Genomic DNA Translation: AAZ74734.1
DQ132113 Genomic DNA Translation: AAZ74718.1
DQ132114 Genomic DNA Translation: AAZ74719.1
RefSeqiNP_197819.2, NM_122337.5 [Q6NMC6-1]

3D structure databases

SMRiQ6NMC6
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ6NMC6, 3 interactors
STRINGi3702.AT5G24310.1

PTM databases

iPTMnetiQ6NMC6

Proteomic databases

PaxDbiQ6NMC6
ProteomicsDBi245085 [Q6NMC6-1]

Genome annotation databases

EnsemblPlantsiAT5G24310.1; AT5G24310.1; AT5G24310 [Q6NMC6-1]
GeneIDi832498
GrameneiAT5G24310.1; AT5G24310.1; AT5G24310 [Q6NMC6-1]
KEGGiath:AT5G24310

Organism-specific databases

AraportiAT5G24310
TAIRilocus:2169759, AT5G24310

Phylogenomic databases

eggNOGiENOG502R3IQ, Eukaryota
HOGENOMiCLU_054853_1_0_1
InParanoidiQ6NMC6
PhylomeDBiQ6NMC6

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q6NMC6

Gene expression databases

ExpressionAtlasiQ6NMC6, baseline and differential
GenevisibleiQ6NMC6, AT

Family and domain databases

InterProiView protein in InterPro
IPR028457, ABI
PANTHERiPTHR10460, PTHR10460, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABIL3_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6NMC6
Secondary accession number(s): Q3YIV3, Q3YIV4, Q9FNF1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 5, 2004
Last modified: February 23, 2022
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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