UniProtKB - Q6NLV4 (FY_ARATH)
Protein
Flowering time control protein FY
Gene
FY
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels. Required for the negative autoregulation of FCA expression. Acts probably as an RNA 3' end-processing factor. Required for growth and development in plants.2 Publications
GO - Biological processi
- cell differentiation Source: UniProtKB-KW
- flower development Source: UniProtKB-KW
- mRNA polyadenylation Source: GO_Central
Keywordsi
Molecular function | Developmental protein |
Biological process | Differentiation, Flowering |
Names & Taxonomyi
Protein namesi | Recommended name: Flowering time control protein FY |
Gene namesi | Name:FY Ordered Locus Names:At5g13480 ORF Names:T6I14.10 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G13480 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- mRNA cleavage and polyadenylation specificity factor complex Source: GO_Central
Keywords - Cellular componenti
NucleusPathology & Biotechi
Disruption phenotypei
Embryo lethal.1 Publication
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 141 | G → S in fy-3; late flowering. 1 Publication | 1 | |
Mutagenesisi | 488 – 494 | PPLPPGP → AAAAAAA: No effect on FCA binding; when associated with 632-AAAAAGAA-639, loss of binding to FCA. 1 Publication | 7 | |
Mutagenesisi | 488 | P → S: Increased FLC levels and late flowering. 1 Publication | 1 | |
Mutagenesisi | 489 | P → S: Increased FLC levels and late flowering. 1 Publication | 1 | |
Mutagenesisi | 632 – 639 | PPLPPGPP → AAAAAGAA: No effect on FCA binding; when associated with 488-AAAAAAA-494, loss of binding to FCA. 1 Publication | 8 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000391779 | 1 – 647 | Flowering time control protein FYAdd BLAST | 647 |
Proteomic databases
PaxDbi | Q6NLV4 |
PRIDEi | Q6NLV4 |
ProteomicsDBi | 230555 [Q6NLV4-1] |
Expressioni
Tissue specificityi
Expressed in embryos, in shoot and root meristems and in the vasculature.1 Publication
Developmental stagei
At globular stage, expressed throughout the embryo, endosperm and surrounding maternal seed tissue. From the heart-stage, expression restricted to the embryo and the funiculus.1 Publication
Gene expression databases
ExpressionAtlasi | Q6NLV4, baseline and differential |
Genevisiblei | Q6NLV4, AT |
Interactioni
Subunit structurei
Interacts transiently (via the PPLPP motifs) with FCA (via the WW domain).
Interacts with CPSF73-I, CPSF73-II, CPSF100 and CPSF160 in the CPSF complex. The FCA/FY interaction leads to changes in FY/CPSF complex composition.
4 PublicationsBinary interactionsi
Hide detailsQ6NLV4
With | #Exp. | IntAct |
---|---|---|
CPSF100 [Q9LKF9] | 3 | EBI-1632908,EBI-1775444 |
CPSF160 [Q9FGR0] | 2 | EBI-1632908,EBI-1775436 |
Protein-protein interaction databases
BioGRIDi | 16469, 11 interactors |
DIPi | DIP-40405N |
IntActi | Q6NLV4, 4 interactors |
STRINGi | 3702.AT5G13480.2 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 121 – 160 | WD 1Add BLAST | 40 | |
Repeati | 163 – 202 | WD 2Add BLAST | 40 | |
Repeati | 205 – 244 | WD 3Add BLAST | 40 | |
Repeati | 247 – 286 | WD 4Add BLAST | 40 | |
Repeati | 289 – 328 | WD 5Add BLAST | 40 | |
Repeati | 331 – 371 | WD 6Add BLAST | 41 | |
Repeati | 375 – 414 | WD 7Add BLAST | 40 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 488 – 492 | PPLPP motif 1 | 5 | |
Motifi | 632 – 636 | PPLPP motif 2 | 5 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 478 – 640 | Pro-richAdd BLAST | 163 | |
Compositional biasi | 503 – 647 | Gln-richAdd BLAST | 145 |
Keywords - Domaini
Repeat, WD repeatPhylogenomic databases
eggNOGi | KOG0284, Eukaryota |
InParanoidi | Q6NLV4 |
PhylomeDBi | Q6NLV4 |
Family and domain databases
Gene3Di | 2.130.10.10, 3 hits |
InterProi | View protein in InterPro IPR020472, G-protein_beta_WD-40_rep IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF00400, WD40, 6 hits |
PRINTSi | PR00320, GPROTEINBRPT |
SMARTi | View protein in SMART SM00320, WD40, 7 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 7 hits PS50294, WD_REPEATS_REGION, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry describes 1 produced by isoform ialternative splicing. AlignAdd to basketNote: A number of isoforms are produced. According to EST sequences.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q6NLV4-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MYAGGDMHRG SQMPQPPMMR QSSASSTNIN PDYHHPSGPF DPNVDSFGAK
60 70 80 90 100
RMRKHTQRRA VDYTSTVVRY IQARTWQRDS RDRTTLQPTP AAAVDMLPTV
110 120 130 140 150
AYSDNPSTSF AAKFVHASLN KNRCSINRVL WTPSGRRLIT GSQSGEFTLW
160 170 180 190 200
NGQSFNFEMI LQAHDQPIRS MVWSHNENYM VSGDDGGTLK YWQNNMNNVK
210 220 230 240 250
ANKTAHKESI RDLSFCKTDL KFCSCSDDTT VKVWDFTKCV DESSLTGHGW
260 270 280 290 300
DVKSVDWHPT KSLLVSGGKD QLVKLWDTRS GRELCSLHGH KNIVLSVKWN
310 320 330 340 350
QNGNWLLTAS KDQIIKLYDI RTMKELQSFR GHTKDVTSLA WHPCHEEYFV
360 370 380 390 400
SGSSDGSICH WIVGHENPQI EIPNAHDNSV WDLAWHPIGY LLCSGSNDHT
410 420 430 440 450
TKFWCRNRPA DNPRDVLMQN QGYNEQGFGR QPDNFQPSEA SPIPGAFVPG
460 470 480 490 500
LTRNEGTIPG IGIAMPFDAS SQGDHKQPLP GSMALGAPPL PPGPHPSLLG
510 520 530 540 550
SGQQQGYQQQ QQHQGHPQQM LPMPNMPHHQ LPPSSHMPLH PHHLPRPMQM
560 570 580 590 600
PPHGHMPPPS MPMSHQMPGS MGMQGGMNPQ MSQSHFMGAP SGVFQGQPNS
610 620 630 640
GGPQMYPQGR GGFNRPQMIP GYNNPFQQQQ QPPLPPGPPP NNNQQHQ
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF4K3Y7 | F4K3Y7_ARATH | Transducin/WD40 repeat-like superfa... | FY At5g13480, T6I14.10, T6I14_10 | 657 | Annotation score: | ||
A0A1P8BCM2 | A0A1P8BCM2_ARATH | Transducin/WD40 repeat-like superfa... | FY At5g13480, T6I14.10, T6I14_10 | 621 | Annotation score: | ||
A0A1P8BCJ2 | A0A1P8BCJ2_ARATH | Transducin/WD40 repeat-like superfa... | FY At5g13480, T6I14.10, T6I14_10 | 635 | Annotation score: |
Sequence cautioni
The sequence CAC05425 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL391710 Genomic DNA Translation: CAC05425.1 Sequence problems. CP002688 Genomic DNA Translation: AED91899.1 BT012225 mRNA Translation: AAS76712.1 |
RefSeqi | NP_196852.3, NM_121351.5 [Q6NLV4-1] |
Genome annotation databases
EnsemblPlantsi | AT5G13480.1; AT5G13480.1; AT5G13480 [Q6NLV4-1] |
GeneIDi | 831191 |
Gramenei | AT5G13480.1; AT5G13480.1; AT5G13480 [Q6NLV4-1] |
KEGGi | ath:AT5G13480 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL391710 Genomic DNA Translation: CAC05425.1 Sequence problems. CP002688 Genomic DNA Translation: AED91899.1 BT012225 mRNA Translation: AAS76712.1 |
RefSeqi | NP_196852.3, NM_121351.5 [Q6NLV4-1] |
3D structure databases
SMRi | Q6NLV4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 16469, 11 interactors |
DIPi | DIP-40405N |
IntActi | Q6NLV4, 4 interactors |
STRINGi | 3702.AT5G13480.2 |
Proteomic databases
PaxDbi | Q6NLV4 |
PRIDEi | Q6NLV4 |
ProteomicsDBi | 230555 [Q6NLV4-1] |
Genome annotation databases
EnsemblPlantsi | AT5G13480.1; AT5G13480.1; AT5G13480 [Q6NLV4-1] |
GeneIDi | 831191 |
Gramenei | AT5G13480.1; AT5G13480.1; AT5G13480 [Q6NLV4-1] |
KEGGi | ath:AT5G13480 |
Organism-specific databases
Araporti | AT5G13480 |
Phylogenomic databases
eggNOGi | KOG0284, Eukaryota |
InParanoidi | Q6NLV4 |
PhylomeDBi | Q6NLV4 |
Miscellaneous databases
PROi | PR:Q6NLV4 |
Gene expression databases
ExpressionAtlasi | Q6NLV4, baseline and differential |
Genevisiblei | Q6NLV4, AT |
Family and domain databases
Gene3Di | 2.130.10.10, 3 hits |
InterProi | View protein in InterPro IPR020472, G-protein_beta_WD-40_rep IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF00400, WD40, 6 hits |
PRINTSi | PR00320, GPROTEINBRPT |
SMARTi | View protein in SMART SM00320, WD40, 7 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 7 hits PS50294, WD_REPEATS_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FY_ARATH | |
Accessioni | Q6NLV4Primary (citable) accession number: Q6NLV4 Secondary accession number(s): Q9FY53 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 2, 2010 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names