UniProtKB - Q6N084 (Q6N084_HUMAN)
Protein
Fibronectin
Gene
DKFZp686L11144
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- heparin binding Source: UniProtKB-KW
GO - Biological processi
- acute-phase response Source: UniProtKB-KW
- cell adhesion Source: UniProtKB-KW
- regulation of cell shape Source: UniProtKB-KW
Keywordsi
Molecular function | Heparin-bindingARBA annotation |
Biological process | Acute phaseARBA annotation, Cell adhesionARBA annotation, Cell shapeARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: FibronectinARBA annotation |
Gene namesi | Name:DKFZp686L11144Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
PTM / Processingi
Keywords - PTMi
Disulfide bondARBA annotation, OxidationARBA annotationProteomic databases
PeptideAtlasi | Q6N084 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 35 | Fibronectin type-IIIInterPro annotationAdd BLAST | 35 | |
Domaini | 38 – 130 | Fibronectin type-IIIInterPro annotationAdd BLAST | 93 | |
Domaini | 131 – 218 | Fibronectin type-IIIInterPro annotationAdd BLAST | 88 | |
Domaini | 219 – 312 | Fibronectin type-IIIInterPro annotationAdd BLAST | 94 | |
Domaini | 313 – 403 | Fibronectin type-IIIInterPro annotationAdd BLAST | 91 | |
Domaini | 404 – 496 | Fibronectin type-IIIInterPro annotationAdd BLAST | 93 | |
Domaini | 497 – 583 | Fibronectin type-IIIInterPro annotationAdd BLAST | 87 | |
Domaini | 584 – 674 | Fibronectin type-IIIInterPro annotationAdd BLAST | 91 | |
Domaini | 753 – 845 | Fibronectin type-IIIInterPro annotationAdd BLAST | 93 | |
Domaini | 852 – 896 | Fibronectin type-IInterPro annotationAdd BLAST | 45 | |
Domaini | 897 – 939 | Fibronectin type-IInterPro annotationAdd BLAST | 43 | |
Domaini | 941 – 981 | Fibronectin type-IInterPro annotationAdd BLAST | 41 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 338 – 362 | DisorderedSequence analysisAdd BLAST | 25 |
Phylogenomic databases
OrthoDBi | 6580at2759 |
Family and domain databases
CDDi | cd00061, FN1, 3 hits cd00063, FN3, 8 hits |
Gene3Di | 2.60.40.10, 9 hits |
InterProi | View protein in InterPro IPR000083, Fibronectin_type1 IPR003961, FN3_dom IPR036116, FN3_sf IPR013783, Ig-like_fold |
Pfami | View protein in Pfam PF00039, fn1, 3 hits PF00041, fn3, 8 hits |
SMARTi | View protein in SMART SM00058, FN1, 3 hits SM00060, FN3, 8 hits |
SUPFAMi | SSF49265, SSF49265, 6 hits |
PROSITEi | View protein in PROSITE PS01253, FN1_1, 1 hit PS51091, FN1_2, 3 hits PS50853, FN3, 9 hits |
i Sequence
Sequence statusi: Fragment.
Q6N084-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
CTFDNLSPGL EYNVSVYTVK DDKESVPISD TIIPAVPPPT DLRFTNIGPD
60 70 80 90 100
TMRVTWAPPP SIDLTNFLVR YSPVKNEEDV AELSISPSDN AVVLTNLLPG
110 120 130 140 150
TEYVVSVSSV YEQHESTPLR GRQKTGLDSP TGIDFSDITA NSFTVHWIAP
160 170 180 190 200
RATITGYRIR HHPEHFSGRP REDRVPHSRN SITLTNLTPG TEYVVSIVAL
210 220 230 240 250
NGREESPLLI GQQSTVSDVP RDLEVVAATP TSLLISWDAP AVTVRYYRIT
260 270 280 290 300
YGETGGNSPV QEFTVPGSKS TATISGLKPG VDYTITVYAV TGRGDSPASS
310 320 330 340 350
KPISINYRTE IDKPSQMQVT DVQDNSISVK WLPSSSPVTG YRVTTTPKNG
360 370 380 390 400
PGPTKTKTAG PDQTEMTIEG LQPTVEYVVS VYAQNPSGES QPLVQTAVTT
410 420 430 440 450
IPAPTDLKFT QVTPTSLSAQ WTPPNVQLTG YRVRVTPKEK TGPMKEINLA
460 470 480 490 500
PDSSSVVVSG LMVATKYEVS VYALKDTLTS RPAQGVVTTL ENVSPPRRAR
510 520 530 540 550
VTDATETTIT ISWRTKTETI TGFQVDAVPA NGQTPIQRTI KPDVRSYTIT
560 570 580 590 600
GLQPGTDYKI YLYTLNDNAR SSPVVIDAST AIDAPSNLRF LATTPNSLLV
610 620 630 640 650
SWQPPRARIT GYIIKYEKPG SPPREVVPRP RPGVTEATIT GLEPGTEYTI
660 670 680 690 700
YVIALKNNQK SEPLIGRKKT DELPQLVTLP HPNLHGPEIL DVPSTVQKTP
710 720 730 740 750
FVTHPGYDTG NGIQLPGTSG QQPSVGQQMI FEEHGFRRTT PPTTATPIRH
760 770 780 790 800
RPRPYPPNVG QEALSQTTIS WAPFQDTSEY IISCHPVGTD EEPLQFRVPG
810 820 830 840 850
TSTSATLTGL TRGATYNIIV EALKDQQRHK VREEVVTVGN SVNEGLNQPT
860 870 880 890 900
DDSCFDPYTV SHYAVGDEWG RMSESGFKLL CQCLGFGSGH FRCDSSRWCH
910 920 930 940 950
DNGVNYKIGE KWDRQGENGQ MMSCTCLGNG KGEFKCDPHE ATCYDDGKTY
960 970 980 990 1000
HVGEQWQKEY LGAICSCTCF GGQRGWRCDN CRRPGGEPSP EGTTGQSYNQ
1010 1020 1030
YSQRYHQRTN TNVNCPIECF MPLDVQADRE DSRE
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX640638 mRNA Translation: CAE45786.1 |
RefSeqi | NP_002017.1, NM_002026.3 |
Genome annotation databases
GeneIDi | 2335 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX640638 mRNA Translation: CAE45786.1 |
RefSeqi | NP_002017.1, NM_002026.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q6N084 |
Protocols and materials databases
DNASUi | 2335 |
Genome annotation databases
GeneIDi | 2335 |
Organism-specific databases
CTDi | 2335 |
PharmGKBi | PA28194 |
Phylogenomic databases
OrthoDBi | 6580at2759 |
Miscellaneous databases
BioGRID-ORCSi | 2335, 5 hits in 997 CRISPR screens |
GenomeRNAii | 2335 |
Gene expression databases
Genevisiblei | Q6N084, HS |
Family and domain databases
CDDi | cd00061, FN1, 3 hits cd00063, FN3, 8 hits |
Gene3Di | 2.60.40.10, 9 hits |
InterProi | View protein in InterPro IPR000083, Fibronectin_type1 IPR003961, FN3_dom IPR036116, FN3_sf IPR013783, Ig-like_fold |
Pfami | View protein in Pfam PF00039, fn1, 3 hits PF00041, fn3, 8 hits |
SMARTi | View protein in SMART SM00058, FN1, 3 hits SM00060, FN3, 8 hits |
SUPFAMi | SSF49265, SSF49265, 6 hits |
PROSITEi | View protein in PROSITE PS01253, FN1_1, 1 hit PS51091, FN1_2, 3 hits PS50853, FN3, 9 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6N084_HUMAN | |
Accessioni | Q6N084Primary (citable) accession number: Q6N084 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |