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Entry version 122 (16 Oct 2019)
Sequence version 2 (23 Jan 2007)
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Protein

Molybdate-anion transporter

Gene

MFSD5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=546 nM for molybdate (when expressed in yeast)1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processIon transport, Transport

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Molybdate-anion transporter
    Alternative name(s):
    Major facilitator superfamily domain-containing protein 5
    Molybdate transporter 2 homolog
    Short name:
    hsMOT2
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:MFSD5
    ORF Names:UNQ832/PRO1759
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

    Organism-specific databases

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:28156 MFSD5

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_Q6N075

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1 – 21HelicalSequence analysisAdd BLAST21
    Transmembranei43 – 63HelicalSequence analysisAdd BLAST21
    Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
    Transmembranei128 – 148HelicalSequence analysisAdd BLAST21
    Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
    Transmembranei195 – 215HelicalSequence analysisAdd BLAST21
    Transmembranei249 – 269HelicalSequence analysisAdd BLAST21
    Transmembranei278 – 298HelicalSequence analysisAdd BLAST21
    Transmembranei311 – 331HelicalSequence analysisAdd BLAST21
    Transmembranei344 – 364HelicalSequence analysisAdd BLAST21
    Transmembranei376 – 396HelicalSequence analysisAdd BLAST21
    Transmembranei409 – 429HelicalSequence analysisAdd BLAST21

    Keywords - Cellular componenti

    Cell membrane, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Organism-specific databases

    Open Targets

    More...
    OpenTargetsi
    ENSG00000182544

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA142671466

    Miscellaneous databases

    Pharos NIH Druggable Genome Knowledgebase

    More...
    Pharosi
    Q6N075

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    MFSD5

    Domain mapping of disease mutations (DMDM)

    More...
    DMDMi
    124015161

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002734011 – 450Molybdate-anion transporterAdd BLAST450

    Proteomic databases

    Encyclopedia of Proteome Dynamics

    More...
    EPDi
    Q6N075

    jPOST - Japan Proteome Standard Repository/Database

    More...
    jPOSTi
    Q6N075

    MassIVE - Mass Spectrometry Interactive Virtual Environment

    More...
    MassIVEi
    Q6N075

    MaxQB - The MaxQuant DataBase

    More...
    MaxQBi
    Q6N075

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q6N075

    PeptideAtlas

    More...
    PeptideAtlasi
    Q6N075

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q6N075

    ProteomicsDB: a multi-organism proteome resource

    More...
    ProteomicsDBi
    32391
    66618 [Q6N075-1]
    66619 [Q6N075-2]

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q6N075

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    Q6N075

    SwissPalm database of S-palmitoylation events

    More...
    SwissPalmi
    Q6N075

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed ubiquitously but at relatively higher levels in the olfactory bulb and the skeletal muscle.1 Publication

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000182544 Expressed in 207 organ(s), highest expression level in lower esophagus mucosa

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q6N075 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q6N075 HS

    Organism-specific databases

    Human Protein Atlas

    More...
    HPAi
    HPA039773

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    124404, 21 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    Q6N075, 67 interactors

    Molecular INTeraction database

    More...
    MINTi
    Q6N075

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000442688

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the major facilitator superfamily.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG4332 Eukaryota
    ENOG410XSP5 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00390000012629

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000239662

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q6N075

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    FESVLYI

    Database of Orthologous Groups

    More...
    OrthoDBi
    565504at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q6N075

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF328562

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR036259 MFS_trans_sf
    IPR008509 MOT2/MFSD5

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR23516 PTHR23516, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF05631 MFS_5, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF103473 SSF103473, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

    This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

    Isoform 1 (identifier: Q6N075-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MLVTAYLAFV GLLASCLGLE LSRCRAKPPG RACSNPSFLR FQLDFYQVYF
    60 70 80 90 100
    LALAADWLQA PYLYKLYQHY YFLEGQIAIL YVCGLASTVL FGLVASSLVD
    110 120 130 140 150
    WLGRKNSCVL FSLTYSLCCL TKLSQDYFVL LVGRALGGLS TALLFSAFEA
    160 170 180 190 200
    WYIHEHVERH DFPAEWIPAT FARAAFWNHV LAVVAGVAAE AVASWIGLGP
    210 220 230 240 250
    VAPFVAAIPL LALAGALALR NWGENYDRQR AFSRTCAGGL RCLLSDRRVL
    260 270 280 290 300
    LLGTIQALFE SVIFIFVFLW TPVLDPHGAP LGIIFSSFMA ASLLGSSLYR
    310 320 330 340 350
    IATSKRYHLQ PMHLLSLAVL IVVFSLFMLT FSTSPGQESP VESFIAFLLI
    360 370 380 390 400
    ELACGLYFPS MSFLRRKVIP ETEQAGVLNW FRVPLHSLAC LGLLVLHDSD
    410 420 430 440 450
    RKTGTRNMFS ICSAVMVMAL LAVVGLFTVV RHDAELRVPS PTEEPYAPEL
    Length:450
    Mass (Da):49,765
    Last modified:January 23, 2007 - v2
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA15D005755941BA7
    GO
    Isoform 2 (identifier: Q6N075-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MEVTAVGEEA...RARVVRGPTM

    Note: No experimental confirmation available.
    Show »
    Length:557
    Mass (Da):61,504
    Checksum:i85CD96E4BF023226
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    F8VV69F8VV69_HUMAN
    Molybdate-anion transporter
    MFSD5
    412Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    <p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence BAC05108 differs from that shown. Probable cloning artifact.Curated
    The sequence CAE45795 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti130L → M in AAH67795 (PubMed:16541075).Curated1
    Sequence conflicti157V → A in BAC11137 (PubMed:16303743).Curated1
    Sequence conflicti425G → E in CAE45795 (PubMed:17974005).Curated1

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0466471M → MEVTAVGEEANQGDLLGFGQ RCCSLGSSNPWLYRTAGIFP EHCTEEKKIGTYFRVAPQAS KSQRSRCHGMAASEARPGEA TAASYGRPFPTHPRRQEFRA RVVRGPTM in isoform 2. Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AY358604 mRNA Translation: AAQ88967.1
    BX640649 mRNA Translation: CAE45795.1 Different initiation.
    AK097576 mRNA Translation: BAC05108.1 Sequence problems.
    AK074684 mRNA Translation: BAC11137.1
    AC021072 Genomic DNA No translation available.
    CH471054 Genomic DNA Translation: EAW96679.1
    BC007703 mRNA Translation: AAH07703.1
    BC067795 mRNA Translation: AAH67795.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS53796.1 [Q6N075-2]
    CCDS8851.1 [Q6N075-1]

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001164261.1, NM_001170790.1 [Q6N075-2]
    NP_116278.3, NM_032889.4 [Q6N075-1]
    XP_005269254.1, XM_005269197.1 [Q6N075-2]
    XP_005269255.1, XM_005269198.4 [Q6N075-1]

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000329548; ENSP00000332624; ENSG00000182544 [Q6N075-1]
    ENST00000534842; ENSP00000442688; ENSG00000182544 [Q6N075-2]

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    84975

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:84975

    UCSC genome browser

    More...
    UCSCi
    uc001sch.3 human [Q6N075-1]

    Keywords - Coding sequence diversityi

    Alternative splicing

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AY358604 mRNA Translation: AAQ88967.1
    BX640649 mRNA Translation: CAE45795.1 Different initiation.
    AK097576 mRNA Translation: BAC05108.1 Sequence problems.
    AK074684 mRNA Translation: BAC11137.1
    AC021072 Genomic DNA No translation available.
    CH471054 Genomic DNA Translation: EAW96679.1
    BC007703 mRNA Translation: AAH07703.1
    BC067795 mRNA Translation: AAH67795.1
    CCDSiCCDS53796.1 [Q6N075-2]
    CCDS8851.1 [Q6N075-1]
    RefSeqiNP_001164261.1, NM_001170790.1 [Q6N075-2]
    NP_116278.3, NM_032889.4 [Q6N075-1]
    XP_005269254.1, XM_005269197.1 [Q6N075-2]
    XP_005269255.1, XM_005269198.4 [Q6N075-1]

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    BioGridi124404, 21 interactors
    IntActiQ6N075, 67 interactors
    MINTiQ6N075
    STRINGi9606.ENSP00000442688

    PTM databases

    iPTMnetiQ6N075
    PhosphoSitePlusiQ6N075
    SwissPalmiQ6N075

    Polymorphism and mutation databases

    BioMutaiMFSD5
    DMDMi124015161

    Proteomic databases

    EPDiQ6N075
    jPOSTiQ6N075
    MassIVEiQ6N075
    MaxQBiQ6N075
    PaxDbiQ6N075
    PeptideAtlasiQ6N075
    PRIDEiQ6N075
    ProteomicsDBi32391
    66618 [Q6N075-1]
    66619 [Q6N075-2]

    Protocols and materials databases

    The DNASU plasmid repository

    More...
    DNASUi
    84975

    Genome annotation databases

    EnsembliENST00000329548; ENSP00000332624; ENSG00000182544 [Q6N075-1]
    ENST00000534842; ENSP00000442688; ENSG00000182544 [Q6N075-2]
    GeneIDi84975
    KEGGihsa:84975
    UCSCiuc001sch.3 human [Q6N075-1]

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    84975

    GeneCards: human genes, protein and diseases

    More...
    GeneCardsi
    MFSD5
    HGNCiHGNC:28156 MFSD5
    HPAiHPA039773
    neXtProtiNX_Q6N075
    OpenTargetsiENSG00000182544
    PharmGKBiPA142671466

    GenAtlas: human gene database

    More...
    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiKOG4332 Eukaryota
    ENOG410XSP5 LUCA
    GeneTreeiENSGT00390000012629
    HOGENOMiHOG000239662
    InParanoidiQ6N075
    OMAiFESVLYI
    OrthoDBi565504at2759
    PhylomeDBiQ6N075
    TreeFamiTF328562

    Miscellaneous databases

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

    More...
    ChiTaRSi
    MFSD5 human

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

    More...
    GenomeRNAii
    84975
    PharosiQ6N075

    Protein Ontology

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    PROi
    PR:Q6N075

    Gene expression databases

    BgeeiENSG00000182544 Expressed in 207 organ(s), highest expression level in lower esophagus mucosa
    ExpressionAtlasiQ6N075 baseline and differential
    GenevisibleiQ6N075 HS

    Family and domain databases

    InterProiView protein in InterPro
    IPR036259 MFS_trans_sf
    IPR008509 MOT2/MFSD5
    PANTHERiPTHR23516 PTHR23516, 1 hit
    PfamiView protein in Pfam
    PF05631 MFS_5, 1 hit
    SUPFAMiSSF103473 SSF103473, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

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    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

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    MobiDBi
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    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMFSD5_HUMAN
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6N075
    Secondary accession number(s): G3V1N7
    , Q6NW04, Q8N7W8, Q8NCK0, Q96IA5
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
    Last sequence update: January 23, 2007
    Last modified: October 16, 2019
    This is version 122 of the entry and version 2 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
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