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UniProtKB - Q6MGC7 (Q6MGC7_RAT)
Protein
Submitted name:
RCG61041, isoform CRA_a
Gene
Zbtb22
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: RCG61041, isoform CRA_aImportedSubmitted name: Zinc finger and BTB domain-containing 22ImportedSubmitted name: Zinc finger protein 297Imported |
Gene namesi | Name:Zbtb22Imported Synonyms:AA926063Imported, B3galt4Imported, Cdk2ap1-ps1Imported, Col11a2Imported, DaxxImported, Hsd17b8Imported, Kifc1Imported, LOC224733l-1Imported, LOC224733l-2Imported, Phf1Imported, Rps25-ps1Imported, RT1-A1Imported, RT1-A2Imported, RT1-A3Imported, RT1-DOaImported, RT1-HbImported, RT1-Ke4Imported, RxrbImported, Sacm2l-ps1Imported, Sacm2l-ps2Imported, Sec61-psImported, Syngap1Imported, Znf297Imported ORF Names:rCG_61041Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1359627, Zbtb22 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000000476, Expressed in testis and 20 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 57 – 121 | BTBInterPro annotationAdd BLAST | 65 | |
Domaini | 483 – 509 | C2H2-typeInterPro annotationAdd BLAST | 27 | |
Domaini | 510 – 537 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 538 – 564 | C2H2-typeInterPro annotationAdd BLAST | 27 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 174 – 217 | DisorderedSequence analysisAdd BLAST | 44 | |
Regioni | 335 – 408 | DisorderedSequence analysisAdd BLAST | 74 | |
Regioni | 567 – 636 | DisorderedSequence analysisAdd BLAST | 70 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 599 – 615 | Polar residuesSequence analysisAdd BLAST | 17 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160991 |
HOGENOMi | CLU_029118_2_0_1 |
OMAi | NRRVWSP |
OrthoDBi | 830409at2759 |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR029833, ZBT22 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR24414:SF4, PTHR24414:SF4, 1 hit |
Pfami | View protein in Pfam PF00651, BTB, 1 hit |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
Q6MGC7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEPSPMSPSG ATLPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ
60 70 80 90 100
RLQGQLCDVS IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM
110 120 130 140 150
DPGAFETVLA SAYTGRLSMA AADIVNFLTV GSVLQMWHIV DKCTELLREG
160 170 180 190 200
RSSAATTTVT AVAAPSVSVP CASVPSGSGG TVAPATVGSV RSHTSSRASE
210 220 230 240 250
NQSPSSSNYF SPRESTDFSS SSQDAFVASA VGSGNRRDGG PVFPVPVVGS
260 270 280 290 300
AGTTSGKLLL EADELCDDGG DGRGAAAPGA GLRRPNCLPA SAVPQKHWVY
310 320 330 340 350
VKRARNCPAP ASLVHQDPDL EDEEEEEDLV LTCEDDEDED LGNGSGVPAG
360 370 380 390 400
GEPEATLSIS DVRTLTEPAE KGEEQVNFCE SSNDFGPYEG GGAGAGLDDP
410 420 430 440 450
GGPTPSSYGL THPPRPLLPL DVPGNQILVF PSSSSQAPGQ PPGNTAEHGA
460 470 480 490 500
VTLGGASAVG LGIPSGSGGT PGGAGNSDGN KIFLCHCGKA FSHKSMRDRH
510 520 530 540 550
VNMHLNLRPF DCPVCNKKFK MKHHLTEHMK THTGLKPYEC SVCAKKFMWR
560 570 580 590 600
DSFMRHRGHC ERRHRMGAGG AASVPGPGPG APTGPALQPK RESSAVGGGS
610 620 630
GDEANSATPP SNRRVWSPPS VHKVEMDFSG GGGAAH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC128962 Genomic DNA No translation available. BC095905 mRNA Translation: AAH95905.1 BX883042 Genomic DNA Translation: CAE83919.1 CH473988 Genomic DNA Translation: EDL96852.1 |
RefSeqi | NP_001009172.1, NM_001009172.3 XP_006256185.1, XM_006256123.3 XP_017457130.1, XM_017601641.1 |
Genome annotation databases
Ensembli | ENSRNOT00000000558; ENSRNOP00000000558; ENSRNOG00000000476 |
GeneIDi | 309630 |
KEGGi | rno:309630 |
UCSCi | RGD:1359627, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC128962 Genomic DNA No translation available. BC095905 mRNA Translation: AAH95905.1 BX883042 Genomic DNA Translation: CAE83919.1 CH473988 Genomic DNA Translation: EDL96852.1 |
RefSeqi | NP_001009172.1, NM_001009172.3 XP_006256185.1, XM_006256123.3 XP_017457130.1, XM_017601641.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000000558 |
Genome annotation databases
Ensembli | ENSRNOT00000000558; ENSRNOP00000000558; ENSRNOG00000000476 |
GeneIDi | 309630 |
KEGGi | rno:309630 |
UCSCi | RGD:1359627, rat |
Organism-specific databases
CTDi | 9278 |
RGDi | 1359627, Zbtb22 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160991 |
HOGENOMi | CLU_029118_2_0_1 |
OMAi | NRRVWSP |
OrthoDBi | 830409at2759 |
Miscellaneous databases
PROi | PR:Q6MGC7 |
Gene expression databases
Bgeei | ENSRNOG00000000476, Expressed in testis and 20 other tissues |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR029833, ZBT22 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR24414:SF4, PTHR24414:SF4, 1 hit |
Pfami | View protein in Pfam PF00651, BTB, 1 hit |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6MGC7_RAT | |
Accessioni | Q6MGC7Primary (citable) accession number: Q6MGC7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | January 19, 2022 | |
This is version 143 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |