Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 135 (02 Dec 2020)
Sequence version 1 (05 Jul 2004)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Superkiller viralicidic activity 2-like (S. cerevisiae)

Gene

Skiv2l

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Superkiller viralicidic activity 2-like (S. cerevisiae)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Skiv2lImported
Synonyms:ApomImported, Bat4Imported, C2Imported, C4aImported, CfbImported, Csnk2bImported, G7eImported, Hspa1aImported, Hspa1bImported, Hspa1lImported, Ly6g5cImported, Ly6g6cImported, Neu1Imported, Ng35Imported, Rps25-ps2Imported, Stk19Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

Rat genome database

More...
RGDi
1303059, Skiv2l

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q6MG76

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6MG76

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6MG76

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q6MG76, 2 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini313 – 469Helicase ATP-bindingInterPro annotationAdd BLAST157
Domaini579 – 749Helicase C-terminalInterPro annotationAdd BLAST171

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni216 – 243DisorderedSequence analysisAdd BLAST28

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002902_1_4_1

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6MG76

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011545, DEAD/DEAH_box_helicase_dom
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR027417, P-loop_NTPase
IPR025696, rRNA_proc-arch_dom
IPR016438, Ski2-like
IPR012961, Ski2_C
IPR040801, Ski2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00270, DEAD, 1 hit
PF08148, DSHCT, 1 hit
PF00271, Helicase_C, 1 hit
PF13234, rRNA_proc-arch, 1 hit
PF17911, Ski2_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF005198, Antiviral_helicase_SKI2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487, DEXDc, 1 hit
SM01142, DSHCT, 1 hit
SM00490, HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6MG76-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMETERLVLP PPDPLNLPLR ALEVGCTGRW ELLNVPGPPE STLPHGLPPC
60 70 80 90 100
APDLCQEAEQ LFLSSPAWLP LHGVEHSARK WQRKTDPWSL LAALGTPVPS
110 120 130 140 150
DLQAQRHPTT GHILGYKEVL LENTNLSATT SLSLRRPPGP ASQSLWGNPT
160 170 180 190 200
QYPFWPGGMD EPSITDLSTR EEAEEEIDFE KDLLTVPPGF KKGVDFAPKA
210 220 230 240 250
PVPGLLSLSR LLEPLDLSGG DEGEGEAAGG PRGDAASASP SSTPLIRASS
260 270 280 290 300
LEDLVLKEAS TVVSTLEPLK PPPQEQWAVP VDVTSPVGDF YRLIPQPAFQ
310 320 330 340 350
WAFEPDVFQK QAILHLEQHD SVFVAAHTSA GKTVVAEYAI ALAQKHMTRT
360 370 380 390 400
IYTSPIKALS NQKFRDFRNT FGDVGLLTGD VQLHPEASCL IMTTEILRSM
410 420 430 440 450
LYSGSDVIRD LEWVIFDEVH YINDAERGVV WEEVLIMLPE HVSIILLSAT
460 470 480 490 500
VPNALEFADW IGRLKRRQIY VISTVARPVP LEHYLFTGNS PKTQGELFLL
510 520 530 540 550
LDSRGAFHTK GYYAAVEAKK ERMSKHAQTF GAKQPTHQGG PAQDRGVYLA
560 570 580 590 600
LLASLRTRAQ LPVVVFTFSR GRCDEQASGL TSLDLTTSSE KSEIHLFLQR
610 620 630 640 650
CLARLRGSDR QLPQVLHMSE LLRRGLGVHH SGILPILKEI VEMLFSRGLV
660 670 680 690 700
KVLFATETFA MGVNMPARTV VFDSMRKHDG STFRDLLPGE YVQMAGRAGR
710 720 730 740 750
RGLDPTGTVI LLCKGRVPEM ADLHRMMMGK PSQLQSQFRL TYTMILNLLR
760 770 780 790 800
VDALRVEDMM KRSFSEFPSR KDSKAHEQAL ADLTKRLGAL EEPDVTGQLA
810 820 830 840 850
DLPEYYSWAE ELTETRNMIQ RRIMESVNGL KSLSVGRVVV VKNEEHHNAL
860 870 880 890 900
GVILQVSSNS TSRVFTTLVL CDKPAVSENP RDKGPATPDV PHPDDLVGFK
910 920 930 940 950
LFLPEGPCEH TVAKLQPGDV AAISTKVLRV NGEKISEDFS KRQQPKFRKD
960 970 980 990 1000
PPLAAVTTAV QELLRLAQAY PAGPPTLDPI NDLQLKDVAV VEGGLRARKL
1010 1020 1030 1040 1050
EELIRGAQCV HSPRFPAQYV KLQERMQIQK EMERLRFLLS DQSLLLLPEY
1060 1070 1080 1090 1100
HQRVEVLRTL GYVDEAGTVK LAGRVACAMS SHELLLTELM FDNALSALRP
1110 1120 1130 1140 1150
EEIAALLSGL VCQSPGDPGD QLPSTLKQGV ERVKAVAKRI GEVQVACGLN
1160 1170 1180 1190 1200
QTVEEFVGEL NFGLVEVVYE WARGMPFSEL AGLSGTPEGL VVRCIQRLAE
1210 1220 1230 1240
MCRSLRGAAR LVGEPVLGAK METAATLLRR DIVFAASLYT Q
Length:1,241
Mass (Da):136,956
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCE286D4DF21EE2C4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX883045 Genomic DNA Translation: CAE83970.1

NCBI Reference Sequences

More...
RefSeqi
NP_998724.1, NM_213559.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
294260

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:294260

UCSC genome browser

More...
UCSCi
RGD:1303059, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883045 Genomic DNA Translation: CAE83970.1
RefSeqiNP_998724.1, NM_213559.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ6MG76, 2 interactors

PTM databases

iPTMnetiQ6MG76
PhosphoSitePlusiQ6MG76

Proteomic databases

PRIDEiQ6MG76

Genome annotation databases

GeneIDi294260
KEGGirno:294260
UCSCiRGD:1303059, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6499
RGDi1303059, Skiv2l

Phylogenomic databases

HOGENOMiCLU_002902_1_4_1
PhylomeDBiQ6MG76

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q6MG76

Family and domain databases

InterProiView protein in InterPro
IPR011545, DEAD/DEAH_box_helicase_dom
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR027417, P-loop_NTPase
IPR025696, rRNA_proc-arch_dom
IPR016438, Ski2-like
IPR012961, Ski2_C
IPR040801, Ski2_N
PfamiView protein in Pfam
PF00270, DEAD, 1 hit
PF08148, DSHCT, 1 hit
PF00271, Helicase_C, 1 hit
PF13234, rRNA_proc-arch, 1 hit
PF17911, Ski2_N, 1 hit
PIRSFiPIRSF005198, Antiviral_helicase_SKI2, 1 hit
SMARTiView protein in SMART
SM00487, DEXDc, 1 hit
SM01142, DSHCT, 1 hit
SM00490, HELICc, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6MG76_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6MG76
Secondary accession number(s): F1LP39
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: December 2, 2020
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again