UniProtKB - Q6MG01 (Q6MG01_RAT)
Protein
Submitted name:
RT1 class I, N3
Gene
RT1-N3
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Biological processi
- antigen processing and presentation of endogenous peptide antigen via MHC class Ib Source: GO_Central
Enzyme and pathway databases
Reactomei | R-RNO-1236974, ER-Phagosome pathway R-RNO-1236977, Endosomal/Vacuolar pathway R-RNO-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-RNO-2172127, DAP12 interactions R-RNO-2424491, DAP12 signaling R-RNO-6798695, Neutrophil degranulation R-RNO-983170, Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
Names & Taxonomyi
Protein namesi | Submitted name: RT1 class I, N3ImportedSubmitted name: RT1 class Ib gene, H2-TL-like, grc region (N3)ImportedSubmitted name: RT1 class Ib, locus N3Imported |
Gene namesi | Name:RT1-N3Imported Synonyms:2310ex4-5Imported, 2331ex4-5Imported, 2361ex4-5Imported, Flot1Imported, Gnl1Imported, Kiaa1949Imported, Rpl41-psImported, Rps2-ps1Imported, Rps2-ps2Imported, RT1-O2Imported, RT1-O3Imported, RT1-S2Imported, RT1-S3Imported, RT1-T24-1Imported, RT1-T24-2Imported, Tubb5Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1598370, RT1-N3 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Extracellular region or secreted
- extracellular space Source: GO_Central
Plasma Membrane
- external side of plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 308 – 332 | HelicalSequence analysisAdd BLAST | 25 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSRNOG00000000795, Expressed in thymus and 19 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 209 – 297 | Ig-likeInterPro annotationAdd BLAST | 89 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 340 – 363 | DisorderedSequence analysisAdd BLAST | 24 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 89 – 109 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the MHC class I family.UniRule annotation
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | ENOG502RQEK, Eukaryota |
GeneTreei | ENSGT00990000203546 |
HOGENOMi | CLU_047501_1_1_1 |
OMAi | AVATCIC |
OrthoDBi | 912212at2759 |
TreeFami | TF336617 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.30.500.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set IPR011161, MHC_I-like_Ag-recog IPR037055, MHC_I-like_Ag-recog_sf IPR011162, MHC_I/II-like_Ag-recog IPR001039, MHC_I_a_a1/a2 |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit PF00129, MHC_I, 1 hit |
PRINTSi | PR01638, MHCCLASSI |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF54452, SSF54452, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6MG01-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLWVPKAAAR WLSALLQILL LNACFSWTWT LVGSHSLRYF STVMSWPGLR
60 70 80 90 100
EPRIIVSGYI DNMEFLRLDS DAETPRVKPL VPWLEQEGLE YLEQQIHRIR
110 120 130 140 150
TQAQQSERNL MTLVRFYNKS MDDFHTLQWQ QGCDVGSDGR LLHWYDQLAF
160 170 180 190 200
DGIDHPTLNK DLRFWTAWTS TVAQISQPEL EARLKDNCSE LLQKYPEKEK
210 220 230 240 250
ERLLRSDPPR AHVTRHPRPE SDVTLRCWAL GFYPADITLT WQLNGEDLIQ
260 270 280 290 300
EMEFVETRPA GDGTFQKWAS VVVPLGKEQK YTCLVEHEGL SEPLTLRWEP
310 320 330 340 350
AQDSTTTIIL IILPTVSAIA LCVAAVATCI CLKKKAGERG RHDTQEADGD
360 370 380 390
SPQDSSKIVV DDQEMEDPFW NTENYRTHLG YRSGTLGFLS LSP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07044362 Genomic DNA No translation available. BC158567 mRNA Translation: AAI58568.1 BX883048 Genomic DNA Translation: CAE84046.1 |
RefSeqi | NP_001008855.1, NM_001008855.2 |
Genome annotation databases
Ensembli | ENSRNOT00000001035; ENSRNOP00000001035; ENSRNOG00000000795 |
GeneIDi | 24750 |
KEGGi | rno:24750 |
UCSCi | RGD:1598370, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07044362 Genomic DNA No translation available. BC158567 mRNA Translation: AAI58568.1 BX883048 Genomic DNA Translation: CAE84046.1 |
RefSeqi | NP_001008855.1, NM_001008855.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000001035 |
Genome annotation databases
Ensembli | ENSRNOT00000001035; ENSRNOP00000001035; ENSRNOG00000000795 |
GeneIDi | 24750 |
KEGGi | rno:24750 |
UCSCi | RGD:1598370, rat |
Organism-specific databases
CTDi | 24750 |
RGDi | 1598370, RT1-N3 |
Phylogenomic databases
eggNOGi | ENOG502RQEK, Eukaryota |
GeneTreei | ENSGT00990000203546 |
HOGENOMi | CLU_047501_1_1_1 |
OMAi | AVATCIC |
OrthoDBi | 912212at2759 |
TreeFami | TF336617 |
Enzyme and pathway databases
Reactomei | R-RNO-1236974, ER-Phagosome pathway R-RNO-1236977, Endosomal/Vacuolar pathway R-RNO-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-RNO-2172127, DAP12 interactions R-RNO-2424491, DAP12 signaling R-RNO-6798695, Neutrophil degranulation R-RNO-983170, Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
Gene expression databases
Bgeei | ENSRNOG00000000795, Expressed in thymus and 19 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.30.500.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set IPR011161, MHC_I-like_Ag-recog IPR037055, MHC_I-like_Ag-recog_sf IPR011162, MHC_I/II-like_Ag-recog IPR001039, MHC_I_a_a1/a2 |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit PF00129, MHC_I, 1 hit |
PRINTSi | PR01638, MHCCLASSI |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF54452, SSF54452, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6MG01_RAT | |
Accessioni | Q6MG01Primary (citable) accession number: Q6MG01 Secondary accession number(s): G5EBE1 V9HVV1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 152 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |