UniProtKB - Q6MFZ6 (Q6MFZ6_RAT)
Protein
Submitted name:
Ribonuclease P 21 subunit (Human), isoform CRA_c
Gene
Rpp21
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- ribonuclease P activity Source: Ensembl
- ribonuclease P RNA binding Source: RGD
GO - Biological processi
- response to drug Source: RGD
- tRNA 5'-leader removal Source: RGD
- tRNA processing Source: GO_Central
Enzyme and pathway databases
Reactomei | R-RNO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol |
Names & Taxonomyi
Protein namesi | Submitted name: Ribonuclease P 21 subunit (Human), isoform CRA_cImportedSubmitted name: Ribonuclease P/MRP subunit p21ImportedSubmitted name: Uncharacterized protein Flj22638Imported |
Gene namesi | Name:Rpp21Imported Synonyms:2781a1Imported, 2788a1a2Imported, 2795a1Imported, 2800a1a2Imported, 2812a1a2Imported, 2824a1Imported, 2829a1a2Imported, 2846a1a2Imported, 2860a1Imported, 2865a2Imported, 2869a1a2Imported, 2879a1Imported, 2886a1-a1a2Imported, 2901a1a2Imported, 2906a1Imported, 2920a1a2Imported, 2927a1Imported, 2941a1a2Imported, 2945a1a2Imported, 2950a1Imported, 2953a1a2Imported, 2959a1Imported, 2976a1Imported, 2981a1a2Imported, 2984a1a2Imported, 2994a1Imported, 3082ex4-5Imported, Flj22638Imported, Nerg-ps11Imported, Nerg-ps12Imported, Nerg-ps13Imported, Nerg-ps14Imported, Nerg-ps15Imported, Rcrg1-ps25Imported, Rcrg1-ps26Imported, Rcrg1-ps27Imported, Rcrg1-ps28Imported, Rcrg1-ps29Imported, Rcrg1-ps30Imported, Rcrg1-ps31Imported, Rcrg1-ps32Imported, Rcrg1-ps33Imported, Rcrg1-ps34Imported, Rcrg1-ps35Imported, Rcrg1-ps36Imported, Rcrg1-ps37Imported, Rcrg1-ps38Imported, Rcrg1-ps39Imported, Rcrg1-ps40Imported, RT1-M10-2Imported, RT1-P2Imported ORF Names:rCG_58581Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1303090, Rpp21 |
Subcellular locationi
Nucleus
- nucleolar ribonuclease P complex Source: GO_Central
Other locations
- multimeric ribonuclease P complex Source: RGD
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000000786, Expressed in liver and 22 other tissues |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 124 – 150 | DisorderedSequence analysisAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 136 – 150 | PolarSequence analysisAdd BLAST | 15 |
Phylogenomic databases
eggNOGi | KOG4394, Eukaryota |
GeneTreei | ENSGT00390000003020 |
HOGENOMi | CLU_079140_2_1_1 |
OMAi | DPKHLLW |
OrthoDBi | 1560813at2759 |
TreeFami | TF323865 |
Family and domain databases
InterProi | View protein in InterPro IPR007175, Rpr2 |
Pfami | View protein in Pfam PF04032, Rpr2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q6MFZ6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGQVKDREA FQRLNFLYQA AHCVLSQNPE NQALARFYCH TEKTIAKRLV
60 70 80 90 100
LRQDPSVKRT LCRDCSSLLI PGLTCTQRQR RRKGQRWTVQ TCLTCQRSQR
110 120 130 140 150
FLNDPKHLLW GDRPEAQLEN QADFKPSEPL PNIADLSKEN VQTQALNTTE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0G2K656 | A0A0G2K656_RAT | Ribonuclease P 21 subunit (Human), ... | Rpp21 rCG_58581 | 69 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC120486 Genomic DNA No translation available. BX883050 Genomic DNA Translation: CAE84051.1 CH474093 Genomic DNA Translation: EDL84590.1 |
RefSeqi | NP_001002831.1, NM_001002831.1 |
Genome annotation databases
Ensembli | ENSRNOT00000001024; ENSRNOP00000001024; ENSRNOG00000000786 |
GeneIDi | 406230 |
KEGGi | rno:406230 |
UCSCi | RGD:1303090, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC120486 Genomic DNA No translation available. BX883050 Genomic DNA Translation: CAE84051.1 CH474093 Genomic DNA Translation: EDL84590.1 |
RefSeqi | NP_001002831.1, NM_001002831.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000001024 |
Genome annotation databases
Ensembli | ENSRNOT00000001024; ENSRNOP00000001024; ENSRNOG00000000786 |
GeneIDi | 406230 |
KEGGi | rno:406230 |
UCSCi | RGD:1303090, rat |
Organism-specific databases
CTDi | 79897 |
RGDi | 1303090, Rpp21 |
Phylogenomic databases
eggNOGi | KOG4394, Eukaryota |
GeneTreei | ENSGT00390000003020 |
HOGENOMi | CLU_079140_2_1_1 |
OMAi | DPKHLLW |
OrthoDBi | 1560813at2759 |
TreeFami | TF323865 |
Enzyme and pathway databases
Reactomei | R-RNO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol |
Miscellaneous databases
PROi | PR:Q6MFZ6 |
Gene expression databases
Bgeei | ENSRNOG00000000786, Expressed in liver and 22 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR007175, Rpr2 |
Pfami | View protein in Pfam PF04032, Rpr2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6MFZ6_RAT | |
Accessioni | Q6MFZ6Primary (citable) accession number: Q6MFZ6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 108 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |