UniProtKB - Q6LY21 (Q6LY21_METMP)
Protein
DNA protection during starvation protein
Gene
MMP1172
Organism
Methanococcus maripaludis (strain S2 / LL)
Status
Functioni
Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction.UniRule annotation
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 30 | IronUniRule annotation | 1 | |
Metal bindingi | 66 | IronUniRule annotation | 1 | |
Metal bindingi | 117 | IronUniRule annotation | 1 | |
Metal bindingi | 149 | IronUniRule annotation | 1 | |
Metal bindingi | 152 | IronUniRule annotation | 1 |
GO - Molecular functioni
- ferric iron binding Source: UniProtKB-UniRule
- oxidoreductase activity Source: UniProtKB-UniRule
GO - Biological processi
- cellular iron ion homeostasis Source: UniProtKB-UniRule
Keywordsi
Molecular function | OxidoreductaseUniRule annotation |
Biological process | Iron storageUniRule annotation |
Ligand | Iron, Metal-bindingUniRule annotation |
Enzyme and pathway databases
BioCyci | MMAR267377:MMP_RS06045-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: DNA protection during starvation proteinUniRule annotation (EC:1.16.-.-UniRule annotation) |
Gene namesi | Ordered Locus Names:MMP1172Imported |
Organismi | Methanococcus maripaludis (strain S2 / LL)Imported |
Taxonomic identifieri | 267377 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Methanomada group › Methanococci › Methanococcales › Methanococcaceae › Methanococcus › |
Proteomesi |
|
Subcellular locationi
Other locations
- nucleoid UniRule annotation
Keywords - Cellular componenti
CytoplasmUniRule annotationInteractioni
Subunit structurei
Homododecamer. The 12 identical subunits form a hollow sphere into which the mineral iron core of up to 300 Fe3+ can be deposited.
UniRule annotationProtein-protein interaction databases
STRINGi | 267377.MMP1172 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 162 | FerritinInterPro annotationAdd BLAST | 142 |
Sequence similaritiesi
Belongs to the Dps family.UniRule annotation
Phylogenomic databases
eggNOGi | arCOG01093, Archaea |
HOGENOMi | CLU_104506_4_0_2 |
OMAi | FYYYTIL |
OrthoDBi | 61631at2157 |
Family and domain databases
CDDi | cd01052, DPSL, 1 hit |
Gene3Di | 1.20.1260.10, 1 hit |
InterProi | View protein in InterPro IPR014490, Dps-like IPR033921, DPSL_diiron-bd_dom IPR012347, Ferritin-like IPR009078, Ferritin-like_SF IPR008331, Ferritin_DPS_dom |
Pfami | View protein in Pfam PF00210, Ferritin, 1 hit |
PIRSFi | PIRSF018063, Ferrtn_UCP018063, 1 hit |
SUPFAMi | SSF47240, SSF47240, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6LY21-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKVSREMVE NSGINVDELV ELLVKNAAAE LTTFYYYTIL RVNLIGLEGE
60 70 80 90 100
GLKEIAETAR IEDRNHFEAL VPRIYELGGS LPKDMKDFHD ISGCPPAYLP
110 120 130 140 150
DDVTDINKLM KVLLQAEQCA VKQYTKICNI TAGKDHRTYD LALAILNEEI
160 170 180
QHESWFSEFL GDGPSGHFLR QGKTSPFVSK FLE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX950229 Genomic DNA Translation: CAF30728.1 |
RefSeqi | WP_011171116.1, NC_005791.1 |
Genome annotation databases
EnsemblBacteriai | CAF30728; CAF30728; MMP1172 |
GeneIDi | 2761462 |
KEGGi | mmp:MMP1172 |
PATRICi | fig|267377.15.peg.1205 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX950229 Genomic DNA Translation: CAF30728.1 |
RefSeqi | WP_011171116.1, NC_005791.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 267377.MMP1172 |
Genome annotation databases
EnsemblBacteriai | CAF30728; CAF30728; MMP1172 |
GeneIDi | 2761462 |
KEGGi | mmp:MMP1172 |
PATRICi | fig|267377.15.peg.1205 |
Phylogenomic databases
eggNOGi | arCOG01093, Archaea |
HOGENOMi | CLU_104506_4_0_2 |
OMAi | FYYYTIL |
OrthoDBi | 61631at2157 |
Enzyme and pathway databases
BioCyci | MMAR267377:MMP_RS06045-MONOMER |
Family and domain databases
CDDi | cd01052, DPSL, 1 hit |
Gene3Di | 1.20.1260.10, 1 hit |
InterProi | View protein in InterPro IPR014490, Dps-like IPR033921, DPSL_diiron-bd_dom IPR012347, Ferritin-like IPR009078, Ferritin-like_SF IPR008331, Ferritin_DPS_dom |
Pfami | View protein in Pfam PF00210, Ferritin, 1 hit |
PIRSFi | PIRSF018063, Ferrtn_UCP018063, 1 hit |
SUPFAMi | SSF47240, SSF47240, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6LY21_METMP | |
Accessioni | Q6LY21Primary (citable) accession number: Q6LY21 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | August 12, 2020 | |
This is version 89 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |