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Protein

Guanylate kinase

Gene

gmk

Organism
Photobacterium profundum (strain SS9)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:PBPRA0191
OrganismiPhotobacterium profundum (strain SS9)
Taxonomic identifieri298386 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
Proteomesi
  • UP000000593 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705811 – 208Guanylate kinaseAdd BLAST208

Proteomic databases

PRIDEiQ6LVP5

Interactioni

Protein-protein interaction databases

STRINGi298386.PBPRA0191

Structurei

3D structure databases

ProteinModelPortaliQ6LVP5
SMRiQ6LVP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 184Guanylate kinase-likeUniRule annotationAdd BLAST181

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6LVP5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKGTLYIVS APSGAGKSSL INALLETNPT YDMKVSVSHT TRGMRPGEEN
60 70 80 90 100
GVHYNFISVE EFTELTEQES FLEHAEVFGN YYGTSRPWIE DQLNKGIDVF
110 120 130 140 150
LDIDWQGARQ IRIQMPAAKS LFILPPSKEE LERRLNARGQ DSETIIARRM
160 170 180 190 200
QEARSEISHY NEYDYVIVND DFDAALMDFK AIIRAERLKQ DKQTAKYNSM

LNALLAEQ
Length:208
Mass (Da):23,749
Last modified:July 5, 2004 - v1
Checksum:i571BBC32FDB4AA53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378663 Genomic DNA Translation: CAG18630.1
RefSeqiWP_011217008.1, NC_006370.1

Genome annotation databases

EnsemblBacteriaiCAG18630; CAG18630; PBPRA0191
KEGGippr:PBPRA0191

Similar proteinsi

Entry informationi

Entry nameiKGUA_PHOPR
AccessioniPrimary (citable) accession number: Q6LVP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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