UniProtKB - Q6LCA9 (Q6LCA9_HUMAN)
Protein
DNA-directed DNA polymerase
Gene
polg
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- EC:2.7.7.7ARBA annotation
GO - Molecular functioni
- DNA binding Source: InterPro
- DNA-directed DNA polymerase activity Source: UniProtKB-EC
GO - Biological processi
- DNA replication Source: InterPro
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:polgImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Mitochondrion
- gamma DNA polymerase complex Source: InterPro
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 121 – 200 | DNApol_ExoInterPro annotationAdd BLAST | 80 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 68 | DisorderedSequence analysisAdd BLAST | 68 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 29 – 67 | PolarSequence analysisAdd BLAST | 39 |
Family and domain databases
InterProi | View protein in InterPro IPR002297, DNA-dir_DNA_pol_A_mt IPR041336, DNApol_Exo |
PANTHERi | PTHR10267, PTHR10267, 1 hit |
Pfami | View protein in Pfam PF18136, DNApol_Exo, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q6LCA9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRLLWRKVA GATVGPGPVP APGRWVSSSV PASDPSDGQR RRQQQQQQQQ
60 70 80 90 100
QQQQQPQQPQ VLSSEGGQLR HNPLDIQMLS RGLHEQIFGQ GGEMPGEAAV
110 120 130 140 150
RRSVEHLQKH GLWGQPAVPL PDVELRLPPL YGDNLDQHFR LLAQKQSLPY
160 170 180 190 200
LEAANLLLQA QLPPKPPAWA WAEGWTRYGP EGEAVPVAIP EERALVFDVE
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 200 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U74651 Genomic DNA Translation: AAB18268.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U74651 Genomic DNA Translation: AAB18268.1 |
3D structure databases
SMRi | Q6LCA9 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | Q6LCA9 |
Miscellaneous databases
ChiTaRSi | POLG, human |
Family and domain databases
InterProi | View protein in InterPro IPR002297, DNA-dir_DNA_pol_A_mt IPR041336, DNApol_Exo |
PANTHERi | PTHR10267, PTHR10267, 1 hit |
Pfami | View protein in Pfam PF18136, DNApol_Exo, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6LCA9_HUMAN | |
Accessioni | Q6LCA9Primary (citable) accession number: Q6LCA9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | October 7, 2020 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |