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UniProtKB - Q6L8G1 (IRT2_ORYSJ)
Protein
Fe(2+) transport protein 2
Gene
IRT2
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Iron transporter that may play a role in the uptake of iron from the rhizosphere across the plasma membrane in the root epidermal layer.
1 PublicationGO - Molecular functioni
- zinc ion transmembrane transporter activity Source: GO_Central
GO - Biological processi
- iron ion homeostasis Source: UniProtKB-KW
- iron ion transport Source: UniProtKB
- zinc ion transmembrane transport Source: GO_Central
Keywordsi
Biological process | Ion transport, Iron transport, Transport |
Ligand | Iron |
Enzyme and pathway databases
PlantReactomei | R-OSA-9025727, Iron uptake and transport in root vascular system |
Names & Taxonomyi
Protein namesi | Recommended name: Fe(2+) transport protein 2Alternative name(s): Fe(II) transport protein 2 Iron-regulated transporter 2 Short name: OsIRT2 |
Gene namesi | Name:IRT2 Ordered Locus Names:Os03g0667300, LOC_Os03g46454 ORF Names:OsJ_12018, OSJNBb0036M02.15 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Multi-pass membrane protein 1 Publication
Plasma Membrane
- plasma membrane Source: UniProtKB
Other locations
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 26 – 55 | ExtracellularSequence analysisAdd BLAST | 30 | |
Transmembranei | 56 – 76 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 77 – 85 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 86 – 106 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 107 – 130 | ExtracellularSequence analysisAdd BLAST | 24 | |
Transmembranei | 131 – 151 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 152 – 215 | CytoplasmicSequence analysisAdd BLAST | 64 | |
Transmembranei | 216 – 236 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 237 – 247 | ExtracellularSequence analysisAdd BLAST | 11 | |
Transmembranei | 248 – 268 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 269 – 278 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 279 – 299 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 300 – 309 | ExtracellularSequence analysis | 10 | |
Transmembranei | 310 – 330 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 331 – 349 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 350 – 370 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 25 | Sequence analysisAdd BLAST | 25 | |
ChainiPRO_0000398324 | 26 – 370 | Fe(2+) transport protein 2Add BLAST | 345 |
Proteomic databases
PaxDbi | Q6L8G1 |
Expressioni
Inductioni
By iron deficiency in roots.1 Publication
Gene expression databases
Genevisiblei | Q6L8G1, OS |
Structurei
3D structure databases
AlphaFoldDBi | Q6L8G1 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1558, Eukaryota |
HOGENOMi | CLU_027089_3_0_1 |
InParanoidi | Q6L8G1 |
OMAi | DTAMAKE |
OrthoDBi | 981397at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR003689, ZIP IPR004698, Zn/Fe_permease_fun/pln |
Pfami | View protein in Pfam PF02535, Zip, 1 hit |
TIGRFAMsi | TIGR00820, zip, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q6L8G1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMMSSSQTPV RIAFVFLVIL AATDAHSDHR TPPPACGGAA VGGECHSVAR
60 70 80 90 100
ALRLKLIAIP AILAASVAGV CLPLFARSVP ALRPDGGLFA VVKAFASGVI
110 120 130 140 150
LGTGYMHVLP DSFNDLTSPC LPRKPWSEFP FAAFVAMLAA VFTLMVDSLM
160 170 180 190 200
LTFHTRGSKG RASSAVAHHG DHGHCHAHAL GQADVAALST TEAADQGSGD
210 220 230 240 250
VEAGNTTKAQ LLRNRVIVQV LEMGIVVHSV VIGLGMGASQ NVCTIRPLVA
260 270 280 290 300
ALCFHQMFEG MGLGGCILQA GYGGRTRSAL VFFFSTTTPF GIALGLALTR
310 320 330 340 350
VYSDSSPTAL VVVGLLNAAS AGLLHYMALV ELLAADFMGP KLQGNVRLQL
360 370
AASLAILLGA GGMSVMAKWA
Sequence cautioni
The sequence AAU89149 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence ABF98082 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB126086 mRNA Translation: BAD18964.1 AC145388 Genomic DNA Translation: AAU89149.1 Different initiation. DP000009 Genomic DNA Translation: ABF98082.1 Different initiation. AP008209 Genomic DNA Translation: BAF12765.2 AP014959 Genomic DNA Translation: BAS85652.1 CM000140 Genomic DNA Translation: EEE59644.1 |
RefSeqi | XP_015629246.1, XM_015773760.1 |
Genome annotation databases
EnsemblPlantsi | Os03t0667300-00; Os03t0667300-00; Os03g0667300 |
GeneIDi | 4333667 |
Gramenei | Os03t0667300-00; Os03t0667300-00; Os03g0667300 |
KEGGi | osa:4333667 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB126086 mRNA Translation: BAD18964.1 AC145388 Genomic DNA Translation: AAU89149.1 Different initiation. DP000009 Genomic DNA Translation: ABF98082.1 Different initiation. AP008209 Genomic DNA Translation: BAF12765.2 AP014959 Genomic DNA Translation: BAS85652.1 CM000140 Genomic DNA Translation: EEE59644.1 |
RefSeqi | XP_015629246.1, XM_015773760.1 |
3D structure databases
AlphaFoldDBi | Q6L8G1 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 4530.OS03T0667300-00 |
Proteomic databases
PaxDbi | Q6L8G1 |
Genome annotation databases
EnsemblPlantsi | Os03t0667300-00; Os03t0667300-00; Os03g0667300 |
GeneIDi | 4333667 |
Gramenei | Os03t0667300-00; Os03t0667300-00; Os03g0667300 |
KEGGi | osa:4333667 |
Phylogenomic databases
eggNOGi | KOG1558, Eukaryota |
HOGENOMi | CLU_027089_3_0_1 |
InParanoidi | Q6L8G1 |
OMAi | DTAMAKE |
OrthoDBi | 981397at2759 |
Enzyme and pathway databases
PlantReactomei | R-OSA-9025727, Iron uptake and transport in root vascular system |
Gene expression databases
Genevisiblei | Q6L8G1, OS |
Family and domain databases
InterProi | View protein in InterPro IPR003689, ZIP IPR004698, Zn/Fe_permease_fun/pln |
Pfami | View protein in Pfam PF02535, Zip, 1 hit |
TIGRFAMsi | TIGR00820, zip, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | IRT2_ORYSJ | |
Accessioni | Q6L8G1Primary (citable) accession number: Q6L8G1 Secondary accession number(s): A0A0P0W188, Q10FH8, Q60DL6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 5, 2010 |
Last sequence update: | July 5, 2004 | |
Last modified: | May 25, 2022 | |
This is version 80 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families