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Protein

Nipped-B-like protein

Gene

Nipbl

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays an important role in the loading of the cohesin complex on to DNA (PubMed:29094699). Forms a heterodimeric complex (also known as cohesin loading complex) with MAU2/SCC4 which mediates the loading of the cohesin complex onto chromatin. Plays a role in cohesin loading at sites of DNA damage. Its recruitement to double-strand breaks (DSBs) sites occurs in a CBX3-, RNF8- and RNF168-dependent manner whereas its recruitement to UV irradiation-induced DNA damage sites occurs in a ATM-, ATR-, RNF8- and RNF168-dependent manner (By similarity). Along with ZNF609, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others (PubMed:28041881).By similarity2 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, Developmental protein
Biological processCell cycle, Transcription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-MMU-2470946 Cohesin Loading onto Chromatin

Names & Taxonomyi

Protein namesi
Recommended name:
Nipped-B-like protein
Alternative name(s):
Delangin homolog
SCC2 homolog
Gene namesi
Name:Nipbl
Synonyms:Scc21 Publication
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1913976 Nipbl

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

Pathology & Biotechi

Disruption phenotypei

Deletion of NIPBL in mouse liver leads to strong depletion of chromatin-bound cohesin and marked reorganization of chromosomal folding. Cells retain transcriptionally active (type A) and transcriptionally inactive (type B) compartments, but lose topologically associating domains (TADs) patterns and TAD-associated peaks of contact enrichment across the whole genome. The compartmentalization of chromatin in cells lacking NIPBL is enhanced around 1.8-fold compared with controls.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002185971 – 2798Nipped-B-like proteinAdd BLAST2798

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei150PhosphoserineCombined sources1
Modified residuei162PhosphoserineBy similarity1
Modified residuei243PhosphoserineBy similarity1
Modified residuei256PhosphoserineCombined sources1
Modified residuei274PhosphoserineCombined sources1
Modified residuei280PhosphoserineCombined sources1
Modified residuei284PhosphoserineCombined sources1
Modified residuei301PhosphoserineCombined sources1
Modified residuei306PhosphoserineCombined sources1
Modified residuei318PhosphoserineCombined sources1
Modified residuei350PhosphoserineBy similarity1
Modified residuei713PhosphothreonineBy similarity1
Modified residuei746PhosphothreonineBy similarity1
Modified residuei906PhosphoserineBy similarity1
Modified residuei1076N6-acetyllysineCombined sources1
Modified residuei1083PhosphoserineCombined sources1
Modified residuei1084PhosphoserineCombined sources1
Modified residuei1090PhosphoserineCombined sources1
Modified residuei1144PhosphoserineCombined sources1
Modified residuei1146PhosphoserineCombined sources1
Modified residuei1148PhosphoserineCombined sources1
Modified residuei1153PhosphotyrosineCombined sources1
Modified residuei1154PhosphoserineCombined sources1
Modified residuei1183PhosphothreonineBy similarity1
Modified residuei1191PhosphoserineBy similarity1
Modified residuei2487PhosphoserineCombined sources1
Modified residuei2503PhosphoserineCombined sources1
Modified residuei2505PhosphoserineCombined sources1
Modified residuei2507PhosphoserineCombined sources1
Modified residuei2509PhosphoserineBy similarity1
Modified residuei2646PhosphoserineBy similarity1
Modified residuei2652PhosphoserineCombined sources1
Modified residuei2661PhosphothreonineCombined sources1
Modified residuei2666PhosphoserineCombined sources1
Isoform 2 (identifier: Q6KCD5-2)
Modified residuei2661PhosphothreonineCombined sources1
Modified residuei2666PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ6KCD5
PeptideAtlasiQ6KCD5
PRIDEiQ6KCD5

PTM databases

iPTMnetiQ6KCD5
PhosphoSitePlusiQ6KCD5

Expressioni

Tissue specificityi

Spermatocytes and oocytes (at protein level).2 Publications

Developmental stagei

Widely expressed at 9.5 and 10.5 dpc, with notable accumulations in limb bud, branchial arch and craniofacial mesenchyme. These regions are involved in patterning of the skeleton and soft tissues of the limbs, jaw and face. Expressed in the developing brain, with enrichment in the ventricular zone at 14.5 dpc (PubMed:28041881).2 Publications

Gene expression databases

BgeeiENSMUSG00000022141 Expressed in 294 organ(s), highest expression level in thymus
CleanExiMM_NIPBL
GenevisibleiQ6KCD5 MM

Interactioni

Subunit structurei

Heterodimerizes with MAU2/SCC4 to form the cohesin loading complex (By similarity). The NIPBL-MAU2 heterodimer interacts with the SMC1A-SMC3 heterodimer and with the cohesin complex composed of SMC1A, SMC3, RAD21 and STAG1. Interacts directly (via PxVxL motif) with CBX3 and CBX5 (By similarity). Interacts with ZNF609 (via N-terminus) (PubMed:28041881). Interacts with the multiprotein complex Integrator (PubMed:28041881).By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

BioGridi214531, 9 interactors
DIPiDIP-56622N
IntActiQ6KCD5, 14 interactors
MINTiQ6KCD5
STRINGi10090.ENSMUSP00000059385

Structurei

3D structure databases

ProteinModelPortaliQ6KCD5
SMRiQ6KCD5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1761 – 1799HEAT 1Add BLAST39
Repeati1837 – 1875HEAT 2Add BLAST39
Repeati1939 – 1978HEAT 3Add BLAST40
Repeati2221 – 2261HEAT 4Add BLAST41
Repeati2307 – 2345HEAT 5Add BLAST39

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi990 – 1003PxVxL motifBy similarityAdd BLAST14

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi418 – 462Gln-richAdd BLAST45

Domaini

Contains one Pro-Xaa-Val-Xaa-Leu (PxVxL) motif, which is required for interaction with chromoshadow domains. This motif requires additional residues -7, -6, +4 and +5 of the central Val which contact the chromoshadow domain.By similarity
The C-terminal region containing HEAT repeats and Pro-Xaa-Val-Xaa-Leu (PxVxL) motif are involved in the recruitment of NIPBL to sites of DNA damage.By similarity

Sequence similaritiesi

Belongs to the SCC2/Nipped-B family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG1020 Eukaryota
ENOG410XP32 LUCA
GeneTreeiENSGT00390000010427
HOGENOMiHOG000113787
HOVERGENiHBG052626
InParanoidiQ6KCD5
KOiK06672
OMAiPKQKGEG
OrthoDBiEOG091G00DH
PhylomeDBiQ6KCD5
TreeFamiTF313121

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR026003 Cohesin_HEAT
IPR024986 Nipped-B_C
IPR033031 SCC2/Nipped-B
PANTHERiPTHR21704 PTHR21704, 2 hits
PfamiView protein in Pfam
PF12765 Cohesin_HEAT, 1 hit
PF12830 Nipped-B_C, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6KCD5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNGDMPHVPI TTLAGIASLT DLLNQLPLPS PLPATTTKSL LFNSRIAEEV
60 70 80 90 100
NCLLACRDDN LVSQLVHSLN QVSTDHIELK DNLGSDDPEG DIPVLLQAVL
110 120 130 140 150
ARSPNVFREK SMQNRYVQSG MMMSQYKLSQ NSMHSSPASS NYQQTTISHS
160 170 180 190 200
PSSRFVPPQT SSGNRFMPQQ NSPVPSPYAP QSPAGYMPYS HPSSYTTHPQ
210 220 230 240 250
MQQASVSSPI VAGGLRNIHD NKVSGPLSGN SANHHADNPR HGSSDDYLHM
260 270 280 290 300
VHRLSSDDGD SSTMRNAASF PLRSPQPVCS PAGSDGTPKG SRPPLILQSQ
310 320 330 340 350
SLPCSSPRDV PPDILLDSPE RKQKKQKKIK LGKDEKDQNE KAAMYDIISS
360 370 380 390 400
PTKDSTKLTL RLSRVRSSDM DQQDDMLSGM ENSNVSENDI PFNVQYPGQT
410 420 430 440 450
SKTPITPQDV NRPLNAAQCL SQQEQTAFLP ANQVPVLQQN TSVATKQPQT
460 470 480 490 500
SVVQNQQQVS QQGPIYDEVE LDALAEIERI ERESAIERER FSKEVQDKDK
510 520 530 540 550
PLKKRKQDSY PQEAGGATGG NRPASQETGS TGNGSRPALM VSIDLHQAGR
560 570 580 590 600
VDSQASITQD SDSIKKPEET KQCNDAPISV LQEDIVGSLK SIPENHPETP
610 620 630 640 650
KKKSDPELSK SEMKQNESRL SESKPNENQL GESKSNESKL ETKTETPTEE
660 670 680 690 700
LKQNENKTTE SKQSESAVVE PKQNENRPCD TKPNDNKQNN TRSENTKARP
710 720 730 740 750
ETPKQKAESR PETPKQKSEG RPETPKQKGD GRPETPKQKS EGRPETPKQK
760 770 780 790 800
GEGRPETPKH RHENRRDSGK PSTEKKPDVS KHKQDIKSDS PRLKSERAEA
810 820 830 840 850
LKQRPDGRWE SLRRDHDSKQ KSDDRGESER HRGDQSRVRR PETLRSSSRN
860 870 880 890 900
DHSTKSDGSK TEKLERKHRH ESGDSRDRPS GEQKSRPDSP RVKQGDTNKS
910 920 930 940 950
RPGFKSPNSK DDKRTEGNRS KVDSNKAHTD NKAEFPSYLL GGRSGALKNF
960 970 980 990 1000
VIPKIKRDKD GNITQETKKM DMKGEQKDKV EKMGLVEDLN KGAKPVVVLQ
1010 1020 1030 1040 1050
KLSLDDVQKL IKDREEKSRS SLKSIKNKPS KSNKGSIDQS VLKELPPELL
1060 1070 1080 1090 1100
AEIESTMPLC ERVKMNKRKR STVNEKPKYA EISSDEDNDS DEAFESSRKR
1110 1120 1130 1140 1150
HKKDDDKAWE YEERDRRSSG DHRRSGHSHD GRRSSGGGRY RNRSPSDSDM
1160 1170 1180 1190 1200
EDYSPPPSLS EVARKMKKKE KQKKRKAYEP KLTPEEMMDS STFKRFTASI
1210 1220 1230 1240 1250
ENILDNLEDM DFTAFGDDDE IPQELLLGKH QLNELGSESA KIKAMGIMDK
1260 1270 1280 1290 1300
LSTDKTVKVL NILEKNIQDG SKLSTLLNHN NDTEEEERLW RDLIMERVTK
1310 1320 1330 1340 1350
SADACLTTIN IMTSPNMPKA VYIEDVIERV IQYTKFHLQN TLYPQYDPVY
1360 1370 1380 1390 1400
RVDPHGGGLL SSKAKRAKCS THKQRVIVML YNKVCDIVSS LSELLEIQLL
1410 1420 1430 1440 1450
TDTTILQVSS MGITPFFVEN VSELQLCAIK LVTAVFSRYE KHRQLILEEI
1460 1470 1480 1490 1500
FTSLARLPTS KRSLRNFRLN SSDVDGEPMY IQMVTALVLQ LIQCVVHLPS
1510 1520 1530 1540 1550
SEKDPNSEED SNKKVDQDVV ITNSYETAMR TAQNFLSIFL KKCGSKQGEE
1560 1570 1580 1590 1600
DYRPLFENFV QDLLSTVNKP EWPAAELLLS LLGRLLVHQF SNKSTEMALR
1610 1620 1630 1640 1650
VASLDYLGTV AARLRKDAVT SKMDQGSIER ILKQVSGGED EIQQLQKALL
1660 1670 1680 1690 1700
DYLDENTETD PSLVFSRKFY IAQWFRDTTL ETEKAMKSQK DEESSDATHH
1710 1720 1730 1740 1750
AKELETTGQI MHRAENRKKF LRSIIKTTPS QFSTLKMNSD TVDYDDACLI
1760 1770 1780 1790 1800
VRYLASMRPF AQSFDIYLTQ ILRVLGENAI AVRTKAMKCL SEVVAVDPSI
1810 1820 1830 1840 1850
LARLDMQRGV HGRLMDNSTS VREAAVELLG RFVLCRPQLA EQYYDMLIER
1860 1870 1880 1890 1900
ILDTGISVRK RVIKILRDIC IEQPTFPKIT EMCVKMIRRV NDEEGIKKLV
1910 1920 1930 1940 1950
NETFQKLWFT PTPHNDKEAM TRKILNITDV VAACRDTGYD WFEQLLQNLL
1960 1970 1980 1990 2000
KSEEDSSYKP VKKACTQLVD NLVEHILKYE ESLADSDNKG VNSGRLVACI
2010 2020 2030 2040 2050
TTLFLFSKIR PQLMVKHAMT MQPYLTTKCS TQNDFMVICN VAKILELVVP
2060 2070 2080 2090 2100
LMEHPSETFL ATIEEDLMKL IIKYGMTVVQ HCVSCLGAVV NKVTQNFKFV
2110 2120 2130 2140 2150
WACFNRYYGA ISKLKSQHQE DPNNTSLLTN KPALLRSLFT VGALCRHFDF
2160 2170 2180 2190 2200
DLEDFKGNSK VNIKDKVLEL LMYFTKHSDE EVQTKAIIGL GFAFIQHPSL
2210 2220 2230 2240 2250
MFEQEVKNLY NSILSDKNSS VNLKIQVLKN LQTYLQEEDT RMQQADRDWK
2260 2270 2280 2290 2300
KVAKQEDLKE MGDVSSGMSS SIMQLYLKQV LEAFFHTQSS VRHFALNVIA
2310 2320 2330 2340 2350
LTLNQGLIHP VQCVPYLIAM GTDPEPAMRN KADQQLVEID KKYAGFIHMK
2360 2370 2380 2390 2400
AVAGMKMSYQ VQQAINTCLK DPVRGFRQDE SSSALCSHLY SMIRGNRQHR
2410 2420 2430 2440 2450
RAFLISLLNL FDDTAKTEVT MLLYIADNLA CFPYQTQEEP LFIMHHIDIT
2460 2470 2480 2490 2500
LSVSGSNLLQ SFKESMVKDK RKERKTSPAK ENESSESEEE VSRPRKSRKR
2510 2520 2530 2540 2550
VDSESDSDSE DDINSVMKCL PENSAPLIEF ANVSQGILLL LMLKQHLKNL
2560 2570 2580 2590 2600
CGFSDSKIQK YSPSESAKVY DKAINRKTGV HFHPKQTLDF LRSDMANSKL
2610 2620 2630 2640 2650
TEDVKRSIVR QYLDFKLLME HLDPDEEEEE GEVSASTNAR NKAITSLLGG
2660 2670 2680 2690 2700
GSPKNNTAAD TEDEESDGED RGGGTSGSLR RSKRNSDSTE LAAQMNESVD
2710 2720 2730 2740 2750
VMDVIAICCP KYKDRPQIAR VVQRTSSGVS VQWMAGSYSG SWTEAKRRDG
2760 2770 2780 2790
RKLVPWVDTI KESDIIYKKI ALTSANKLTN KVVQTLRSLY AAKDGTSS
Length:2,798
Mass (Da):315,450
Last modified:July 5, 2004 - v1
Checksum:iBC23B6E2C949C9B3
GO
Isoform 2 (identifier: Q6KCD5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2678-2691: SLRRSKRNSDSTEL → VRRRRSQRISQRIT
     2692-2798: Missing.

Show »
Length:2,691
Mass (Da):303,763
Checksum:i15871B1EF11857A7
GO
Isoform 3 (identifier: Q6KCD5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-2694: Missing.

Note: No experimental confirmation available.
Show »
Length:104
Mass (Da):11,598
Checksum:i48CCA6BE60A266F2
GO
Isoform 4 (identifier: Q6KCD5-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-263: Missing.
     499-556: DKPLKKRKQD...QAGRVDSQAS → GKGPLSLLLQ...NYITLFELLY
     557-2798: Missing.

Note: No experimental confirmation available.
Show »
Length:293
Mass (Da):32,742
Checksum:i946EB9CB53827AE3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti2577K → I in BAC25453 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0110941 – 2694Missing in isoform 3. 1 PublicationAdd BLAST2694
Alternative sequenceiVSP_0110951 – 263Missing in isoform 4. 1 PublicationAdd BLAST263
Alternative sequenceiVSP_011096499 – 556DKPLK…DSQAS → GKGPLSLLLQHLATCVLIPT SLLRYEFHSLAEASISDLII QYHRLSNLNYITLFELLY in isoform 4. 1 PublicationAdd BLAST58
Alternative sequenceiVSP_011097557 – 2798Missing in isoform 4. 1 PublicationAdd BLAST2242
Alternative sequenceiVSP_0110982678 – 2691SLRRS…DSTEL → VRRRRSQRISQRIT in isoform 2. 2 PublicationsAdd BLAST14
Alternative sequenceiVSP_0110992692 – 2798Missing in isoform 2. 2 PublicationsAdd BLAST107

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ627033 mRNA Translation: CAF25291.1
AJ640138 mRNA Translation: CAG26692.1
AK014915 mRNA Translation: BAC25453.1
AK016861 mRNA Translation: BAB30471.1
AK049588 mRNA Translation: BAC33829.1
BC055787 mRNA Translation: AAH55787.1
CCDSiCCDS37035.1 [Q6KCD5-1]
RefSeqiNP_081983.2, NM_027707.3 [Q6KCD5-1]
NP_957684.1, NM_201232.2 [Q6KCD5-2]
XP_006520057.1, XM_006519994.3 [Q6KCD5-1]
XP_006520058.1, XM_006519995.2 [Q6KCD5-1]
XP_017172234.1, XM_017316745.1 [Q6KCD5-1]
UniGeneiMm.240329
Mm.440537

Genome annotation databases

EnsembliENSMUST00000052965; ENSMUSP00000059385; ENSMUSG00000022141 [Q6KCD5-1]
GeneIDi71175
KEGGimmu:71175
UCSCiuc007veq.2 mouse [Q6KCD5-1]
uc007ver.2 mouse [Q6KCD5-2]
uc007vev.1 mouse [Q6KCD5-4]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ627033 mRNA Translation: CAF25291.1
AJ640138 mRNA Translation: CAG26692.1
AK014915 mRNA Translation: BAC25453.1
AK016861 mRNA Translation: BAB30471.1
AK049588 mRNA Translation: BAC33829.1
BC055787 mRNA Translation: AAH55787.1
CCDSiCCDS37035.1 [Q6KCD5-1]
RefSeqiNP_081983.2, NM_027707.3 [Q6KCD5-1]
NP_957684.1, NM_201232.2 [Q6KCD5-2]
XP_006520057.1, XM_006519994.3 [Q6KCD5-1]
XP_006520058.1, XM_006519995.2 [Q6KCD5-1]
XP_017172234.1, XM_017316745.1 [Q6KCD5-1]
UniGeneiMm.240329
Mm.440537

3D structure databases

ProteinModelPortaliQ6KCD5
SMRiQ6KCD5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi214531, 9 interactors
DIPiDIP-56622N
IntActiQ6KCD5, 14 interactors
MINTiQ6KCD5
STRINGi10090.ENSMUSP00000059385

PTM databases

iPTMnetiQ6KCD5
PhosphoSitePlusiQ6KCD5

Proteomic databases

PaxDbiQ6KCD5
PeptideAtlasiQ6KCD5
PRIDEiQ6KCD5

Protocols and materials databases

DNASUi71175
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000052965; ENSMUSP00000059385; ENSMUSG00000022141 [Q6KCD5-1]
GeneIDi71175
KEGGimmu:71175
UCSCiuc007veq.2 mouse [Q6KCD5-1]
uc007ver.2 mouse [Q6KCD5-2]
uc007vev.1 mouse [Q6KCD5-4]

Organism-specific databases

CTDi25836
MGIiMGI:1913976 Nipbl

Phylogenomic databases

eggNOGiKOG1020 Eukaryota
ENOG410XP32 LUCA
GeneTreeiENSGT00390000010427
HOGENOMiHOG000113787
HOVERGENiHBG052626
InParanoidiQ6KCD5
KOiK06672
OMAiPKQKGEG
OrthoDBiEOG091G00DH
PhylomeDBiQ6KCD5
TreeFamiTF313121

Enzyme and pathway databases

ReactomeiR-MMU-2470946 Cohesin Loading onto Chromatin

Miscellaneous databases

PROiPR:Q6KCD5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022141 Expressed in 294 organ(s), highest expression level in thymus
CleanExiMM_NIPBL
GenevisibleiQ6KCD5 MM

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR026003 Cohesin_HEAT
IPR024986 Nipped-B_C
IPR033031 SCC2/Nipped-B
PANTHERiPTHR21704 PTHR21704, 2 hits
PfamiView protein in Pfam
PF12765 Cohesin_HEAT, 1 hit
PF12830 Nipped-B_C, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiNIPBL_MOUSE
AccessioniPrimary (citable) accession number: Q6KCD5
Secondary accession number(s): Q6KC78
, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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