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Protein

Actin-related protein 3

Gene

ARP3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Regulates the directionality of cell expansion by regulating the actin organization, and thus the microtubules distribution and the fusion of small vacuoles (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-binding, Developmental protein
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-OSA-5663213 RHO GTPases Activate WASPs and WAVEs

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein 3
Gene namesi
Name:ARP3
Ordered Locus Names:Os02g0596900, LOC_Os02g38340
ORF Names:OJ1568_B05.15, OsJ_007159, OsJ_07378Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003205261 – 428Actin-related protein 3Add BLAST428

Proteomic databases

PaxDbiQ6K908

Expressioni

Gene expression databases

ExpressionAtlasiQ6K908 differential
GenevisibleiQ6K908 OS

Interactioni

Subunit structurei

Component of the Arp2/3 complex.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g38340.1

Structurei

3D structure databases

ProteinModelPortaliQ6K908
SMRiQ6K908
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family. ARP3 subfamily.Curated

Phylogenomic databases

eggNOGiKOG0678 Eukaryota
COG5277 LUCA
InParanoidiQ6K908
KOiK18584
OMAiYVCQDIV
OrthoDBiEOG09360959

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR015623 Arp3
PANTHERiPTHR11937 PTHR11937, 1 hit
PTHR11937:SF258 PTHR11937:SF258, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 1 hit
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q6K908-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAASRPAVV IDNGTGYTKM GFAGNVEPCF ITPTVVAVND TFAGQTRANT
60 70 80 90 100
TKGNWMAQHS AGVMADLDFF IGEDALARSR SSNTYNLSYP IHNGQVENWD
110 120 130 140 150
TMERFWQQCI FNYLRCDPED HYFLLTESPL TPPETREYTG EIMFETFNVP
160 170 180 190 200
GLYIACQPVL ALAAGYTTTK CEMTGVVVDV GDGATHIVPV ADGYVIGSSI
210 220 230 240 250
RSIPITGKDV TQFIQQLLKE RGEHIPPEES FDVARRVKEM YCYTCSDIVK
260 270 280 290 300
EFNKHDREPN KYIKHWSGIK PKTGAKYTCD IGYERFLGPE IFFHPEIYNN
310 320 330 340 350
DFTTPLHVVI DKCIQSSPID TRRALYKNIV LSGGSTMFKD FHRRLQRDLK
360 370 380 390 400
KIVDARVLAS NARLGGDAKA QPIEVNVVSH PIQRYAVWFG GSVLASTAEF
410 420
YEACHTKAEY EEYGASICRT NPVFKGMY
Length:428
Mass (Da):48,060
Last modified:July 5, 2004 - v1
Checksum:iC1CD7734FFE6B0E3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti197Missing in AK101163 (PubMed:12869764).Curated1
Sequence conflicti422P → T in AK101163 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004092 Genomic DNA Translation: BAD21625.1
AP008208 Genomic DNA Translation: BAF09237.1
AP014958 Genomic DNA Translation: BAS79560.1
CM000139 Genomic DNA Translation: EEE57301.1
AK101163 mRNA No translation available.
RefSeqiXP_015623040.1, XM_015767554.1
UniGeneiOs.24543

Genome annotation databases

EnsemblPlantsiOs02t0596900-01; Os02t0596900-01; Os02g0596900
GeneIDi4329867
GrameneiOs02t0596900-01; Os02t0596900-01; Os02g0596900
KEGGiosa:4329867

Similar proteinsi

Entry informationi

Entry nameiARP3_ORYSJ
AccessioniPrimary (citable) accession number: Q6K908
Secondary accession number(s): A3A8N7, B9F0V9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

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