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Protein

Ubiquitin carboxyl-terminal hydrolase

Gene

P0474F11.34-1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei82NucleophileUniRule annotation1
Active sitei157Proton donorUniRule annotation1
Sitei172Important for enzyme activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseUniRule annotation
Biological processUbl conjugation pathwayUniRule annotation

Enzyme and pathway databases

ReactomeiR-OSA-5689603 UCH proteinases

Protein family/group databases

MEROPSiC12.A01

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin carboxyl-terminal hydrolaseUniRule annotation (EC:3.4.19.12UniRule annotation)
Gene namesi
Name:P0474F11.34-1Imported
Synonyms:OJ1119_A01.19-1Imported
Ordered Locus Names:Os02g0822200Imported
ORF Names:OsJ_08921Imported, OSNPB_020822200Imported
OrganismiOryza sativa subsp. japonica (Rice)Imported
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

Expressioni

Gene expression databases

ExpressionAtlasiQ6K6Z5 differential

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g57630.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 206UCH_1InterPro annotationAdd BLAST204

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili218 – 272Sequence analysisAdd BLAST55

Sequence similaritiesi

Belongs to the peptidase C12 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2778 Eukaryota
ENOG410XP0P LUCA
KOiK05610
OMAiTIQNACA
OrthoDBiEOG09360FQR

Family and domain databases

Gene3Di3.40.532.10, 1 hit
InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR001578 Peptidase_C12_UCH
IPR036959 Peptidase_C12_UCH_sf
IPR017390 Ubiquitinyl_hydrolase_UCH37
PANTHERiPTHR10589 PTHR10589, 1 hit
PfamiView protein in Pfam
PF01088 Peptidase_C12, 1 hit
PIRSFiPIRSF038120 Ubiquitinyl_hydrolase_UCH37, 1 hit
PRINTSiPR00707 UBCTHYDRLASE
SUPFAMiSSF54001 SSF54001, 1 hit

Sequencei

Sequence statusi: Complete.

Q6K6Z5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWCTIESDP GVFTELIQEM QVKGVQVEEL YSLDVDSISE LRPVYGLIFL
60 70 80 90 100
FKWMAGEKDE RPVVKDPNPN LFFASQVIPN ACATQAILSI LMNRPEIDIG
110 120 130 140 150
PELSNLKEFT GAFAPDMKGL AINNSDSIRT AHNSFARPEP FVSDEQRAAG
160 170 180 190 200
KDDEVYHFIS YLPFEGVLYE LDGLKEGPIS LGQCSGGPDD LDWLRMVQPV
210 220 230 240 250
IQKRIERYSQ SEIRFNLMAI IKNRKDVYTA ELKELEKRRD QLLQEMNESS
260 270 280 290 300
AAESLNSELA EVTSAIETVS EKIIMEEEKF KKWRTENIRR KHNYIPFLFN
310 320 330
FLKMLAEKKQ LKPLVEKAKQ QKASSTSTSA R
Length:331
Mass (Da):37,796
Last modified:July 5, 2004 - v1
Checksum:i8D2E466256964815
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004020 Genomic DNA Translation: BAD22892.1
AP004878 Genomic DNA Translation: BAD23124.1
AP008208 Genomic DNA Translation: BAF10471.1
AK058380 mRNA Translation: BAG86677.1
AP014958 Genomic DNA Translation: BAS81641.1
CM000139 Genomic DNA Translation: EAZ25121.1
RefSeqiXP_015627467.1, XM_015771981.1
XP_015627468.1, XM_015771982.1
UniGeneiOs.7211

Genome annotation databases

EnsemblPlantsiOs02t0822200-01; Os02t0822200-01; Os02g0822200
GeneIDi4331185
GrameneiOs02t0822200-01; Os02t0822200-01; Os02g0822200
KEGGiosa:4331185

Similar proteinsi

Entry informationi

Entry nameiQ6K6Z5_ORYSJ
AccessioniPrimary (citable) accession number: Q6K6Z5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 20, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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