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Entry version 122 (02 Dec 2020)
Sequence version 1 (05 Jul 2004)
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Protein

CapZ-interacting protein

Gene

RCSD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Stress-induced phosphorylation of CAPZIP may regulate the ability of F-actin-capping protein to remodel actin filament assembly.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: BHF-UCL

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6JBY9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CapZ-interacting protein
Alternative name(s):
Protein kinase substrate CapZIP
RCSD domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RCSD1
Synonyms:CAPZIP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...
EuPathDBi
HostDB:ENSG00000198771.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28310, RCSD1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610579, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6JBY9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
92241

Open Targets

More...
OpenTargetsi
ENSG00000198771

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671088

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6JBY9, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RCSD1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74758031

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003202621 – 416CapZ-interacting proteinAdd BLAST416

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei17PhosphoserineCombined sources1
Modified residuei68Phosphoserine; by MAPK8; in vitroCombined sources1 Publication1
Modified residuei82PhosphoserineCombined sources1
Modified residuei83Phosphoserine; by MAPK8; in vitroCombined sources1 Publication1
Modified residuei105PhosphoserineCombined sources1
Modified residuei108Phosphoserine; by MAPK12 and MAPK13Combined sources1 Publication1
Modified residuei116PhosphoserineCombined sources1
Modified residuei120PhosphoserineCombined sources1
Modified residuei123PhosphoserineCombined sources1
Modified residuei124PhosphothreonineBy similarity1
Modified residuei126PhosphoserineBy similarity1
Modified residuei127PhosphoserineCombined sources1
Modified residuei135PhosphoserineBy similarity1
Modified residuei143PhosphoserineBy similarity1
Modified residuei177PhosphoserineCombined sources1
Modified residuei179Phosphoserine; by MAPKAPK2 and MAPKAPK3Combined sources1 Publication1
Modified residuei216Phosphoserine; by MAPK8; in vitroCombined sources1 Publication1
Modified residuei244Phosphoserine; by MAPKAPK2 or MAPKAPK3; in vitro1 Publication1
Modified residuei267PhosphoserineCombined sources1
Modified residuei268PhosphoserineCombined sources1
Modified residuei284PhosphoserineCombined sources1
Modified residuei298PhosphoserineCombined sources1
Modified residuei333PhosphoserineCombined sources1
Modified residuei336PhosphothreonineCombined sources1
Modified residuei351PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Dephosphorylation results in its dissociation from CAPZA2.

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
CPTAC-998

Encyclopedia of Proteome Dynamics

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EPDi
Q6JBY9

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q6JBY9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6JBY9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6JBY9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6JBY9

PeptideAtlas

More...
PeptideAtlasi
Q6JBY9

PRoteomics IDEntifications database

More...
PRIDEi
Q6JBY9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66511 [Q6JBY9-1]
66512 [Q6JBY9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6JBY9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6JBY9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in skeletal muscle and more weakly in cardiac muscle. Also expressed in several lymphoid organs, including spleen, thymus, peripheral blood leukocytes, lymph node and bone marrow.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198771, Expressed in leukocyte and 196 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6JBY9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6JBY9, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000198771, Tissue enhanced (blood, lymphoid tissue, skeletal muscle)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CAPZA2 and CAPZB.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124921, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q6JBY9, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356828

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6JBY9, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini227 – 330RCSDAdd BLAST104

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502SRPU, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153997

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_039301_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6JBY9

Identification of Orthologs from Complete Genome Data

More...
OMAi
NACHPPK

Database of Orthologous Groups

More...
OrthoDBi
1408738at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6JBY9

TreeFam database of animal gene trees

More...
TreeFami
TF334159

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029341, FAM21/CAPZIP
IPR007850, RCSD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15255, CAP-ZIP_m, 1 hit
PF05177, RCSD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6JBY9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEERPAETNA NVDNSASPSV AQLAGRFREQ AAAAKETPAS KPTRRKPPCS
60 70 80 90 100
LPLFPPKVDL GQNGEEKSPP NASHPPKFKV KSSPLIEKLQ ANLTFDPAAL
110 120 130 140 150
LPGASPKSPG LKAMVSPFHS PPSTPSSPGV RSRPSEAEEV PVSFDQPPEG
160 170 180 190 200
SHLPCYNKVR TRGSIKRRPP SRRFRRSQSD CGELGDFRAV ESSQQNGAKE
210 220 230 240 250
EDGDEVLPSK SKAPGSPLSS EGAAGEGVRT LGPAEKPPLR RSPSRTEKQE
260 270 280 290 300
EDRATEEAKN GEKARRSSEE VDGQHPAQEE VPESPQTSGP EAENRCGSPR
310 320 330 340 350
EEKPAGEEAE MEKATEVKGE RVQNEEVGPE HDSQETKKLE EGAAVKETPH
360 370 380 390 400
SPPGGVKGGD VPKQEKGKEK QQEGAVLEPG CSPQTGPAQL ETSSEVQSEP
410
AVPKPEDDTP VQDTKM
Length:416
Mass (Da):44,504
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE3E617250F965136
GO
Isoform 2 (identifier: Q6JBY9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-310: Missing.

Show »
Length:106
Mass (Da):11,299
Checksum:iEE22246AC4CFF625
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B7ZKW8B7ZKW8_HUMAN
CapZ-interacting protein
RCSD1
386Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6T4W9F6T4W9_HUMAN
CapZ-interacting protein
RCSD1
197Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB70910 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti48P → A in AAN52359 (Ref. 2) Curated1
Sequence conflicti74H → Q in AAN52359 (Ref. 2) Curated1
Sequence conflicti96D → E in AAN52359 (Ref. 2) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_039181384Q → R. Corresponds to variant dbSNP:rs34699420Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0316481 – 310Missing in isoform 2. 1 PublicationAdd BLAST310

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY530954 mRNA Translation: AAS99235.1
AF545852 mRNA Translation: AAN52359.1
CH471067 Genomic DNA Translation: EAW90797.1
AL031733 Genomic DNA No translation available.
AL356532 Genomic DNA No translation available.
BC072399 mRNA Translation: AAH72399.1
BC098426 mRNA Translation: AAH98426.1
BC101536 mRNA Translation: AAI01537.1
BC101562 mRNA Translation: AAI01563.1
BC013186 mRNA Translation: AAH13186.1
AL137762 mRNA Translation: CAB70910.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1263.1 [Q6JBY9-1]

NCBI Reference Sequences

More...
RefSeqi
NP_443094.3, NM_052862.3 [Q6JBY9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367854; ENSP00000356828; ENSG00000198771 [Q6JBY9-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
92241

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:92241

UCSC genome browser

More...
UCSCi
uc001gem.4, human [Q6JBY9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY530954 mRNA Translation: AAS99235.1
AF545852 mRNA Translation: AAN52359.1
CH471067 Genomic DNA Translation: EAW90797.1
AL031733 Genomic DNA No translation available.
AL356532 Genomic DNA No translation available.
BC072399 mRNA Translation: AAH72399.1
BC098426 mRNA Translation: AAH98426.1
BC101536 mRNA Translation: AAI01537.1
BC101562 mRNA Translation: AAI01563.1
BC013186 mRNA Translation: AAH13186.1
AL137762 mRNA Translation: CAB70910.1 Different initiation.
CCDSiCCDS1263.1 [Q6JBY9-1]
RefSeqiNP_443094.3, NM_052862.3 [Q6JBY9-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi124921, 8 interactors
IntActiQ6JBY9, 4 interactors
STRINGi9606.ENSP00000356828

PTM databases

iPTMnetiQ6JBY9
PhosphoSitePlusiQ6JBY9

Polymorphism and mutation databases

BioMutaiRCSD1
DMDMi74758031

Proteomic databases

CPTACiCPTAC-998
EPDiQ6JBY9
jPOSTiQ6JBY9
MassIVEiQ6JBY9
MaxQBiQ6JBY9
PaxDbiQ6JBY9
PeptideAtlasiQ6JBY9
PRIDEiQ6JBY9
ProteomicsDBi66511 [Q6JBY9-1]
66512 [Q6JBY9-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
34342, 70 antibodies

Genome annotation databases

EnsembliENST00000367854; ENSP00000356828; ENSG00000198771 [Q6JBY9-1]
GeneIDi92241
KEGGihsa:92241
UCSCiuc001gem.4, human [Q6JBY9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92241
DisGeNETi92241
EuPathDBiHostDB:ENSG00000198771.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RCSD1
HGNCiHGNC:28310, RCSD1
HPAiENSG00000198771, Tissue enhanced (blood, lymphoid tissue, skeletal muscle)
MIMi610579, gene
neXtProtiNX_Q6JBY9
OpenTargetsiENSG00000198771
PharmGKBiPA142671088

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502SRPU, Eukaryota
GeneTreeiENSGT00940000153997
HOGENOMiCLU_039301_1_0_1
InParanoidiQ6JBY9
OMAiNACHPPK
OrthoDBi1408738at2759
PhylomeDBiQ6JBY9
TreeFamiTF334159

Enzyme and pathway databases

PathwayCommonsiQ6JBY9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
92241, 6 hits in 844 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RCSD1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
92241
PharosiQ6JBY9, Tbio

Protein Ontology

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PROi
PR:Q6JBY9
RNActiQ6JBY9, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000198771, Expressed in leukocyte and 196 other tissues
ExpressionAtlasiQ6JBY9, baseline and differential
GenevisibleiQ6JBY9, HS

Family and domain databases

InterProiView protein in InterPro
IPR029341, FAM21/CAPZIP
IPR007850, RCSD
PfamiView protein in Pfam
PF15255, CAP-ZIP_m, 1 hit
PF05177, RCSD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCPZIP_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6JBY9
Secondary accession number(s): B1AK48
, Q4G0E7, Q6IN93, Q8IZM2, Q96DX0, Q9NST4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 5, 2004
Last modified: December 2, 2020
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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