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Protein

Succinate receptor 1

Gene

Sucnr1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Receptor for succinate.1 Publication

GO - Molecular functioni

  • G-protein coupled receptor activity Source: RGD

GO - Biological processi

  • G-protein coupled receptor signaling pathway Source: RGD

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate receptor 1
Alternative name(s):
G-protein coupled receptor 91
Gene namesi
Name:Sucnr1
Synonyms:Gpr91
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1303193 Sucnr1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 27ExtracellularSequence analysisAdd BLAST27
Transmembranei28 – 48Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini49 – 55CytoplasmicSequence analysis7
Transmembranei56 – 76Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini77 – 99ExtracellularSequence analysisAdd BLAST23
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 133CytoplasmicSequence analysisAdd BLAST13
Transmembranei134 – 154Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini155 – 181ExtracellularSequence analysisAdd BLAST27
Transmembranei182 – 202Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini203 – 226CytoplasmicSequence analysisAdd BLAST24
Transmembranei227 – 247Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini248 – 276ExtracellularSequence analysisAdd BLAST29
Transmembranei277 – 297Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini298 – 317CytoplasmicSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL2150839
GuidetoPHARMACOLOGYi166

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003835941 – 317Succinate receptor 1Add BLAST317

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi4N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi91 ↔ 168PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ6IYF9

PTM databases

PhosphoSitePlusiQ6IYF9

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018767

Chemistry databases

BindingDBiQ6IYF9

Structurei

3D structure databases

ProteinModelPortaliQ6IYF9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJKI Eukaryota
ENOG410YANU LUCA
HOGENOMiHOG000231307
InParanoidiQ6IYF9
KOiK10042
PhylomeDBiQ6IYF9

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IYF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQNLSCENW LALENILKKY YLSAFYGIEF IVGMLGNFTV VFGYLFCMKN
60 70 80 90 100
WNSSNVYLFN LSISDLAFLC TLPMLIRSYA TGNWTYGDVL CISNRYVLHA
110 120 130 140 150
NLYTSILFLT FISIDRYLLM KFPFREHILQ KKEFAILISL AVWVLVTLEV
160 170 180 190 200
LPMLTFITST PIEKGDSCVD YASSGNPKYS LIYSLCLTLL GFLIPLSVMC
210 220 230 240 250
FFYYKMVVFL KKRSQQQATV LSLNKPLRLV VLAVVIFSVL FTPYHIMRNV
260 270 280 290 300
RIASRLDSWP QGCSQKAIKC LYILTRPLAF LNSAVNPIFY FLVGDHFRDM
310
LFSKLRQYFK SLTSFRL
Length:317
Mass (Da):36,679
Last modified:July 5, 2004 - v1
Checksum:i5971EFB7ABF6113B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY612851 mRNA Translation: AAT10590.1
RefSeqiNP_001001518.1, NM_001001518.1
UniGeneiRn.124512

Genome annotation databases

GeneIDi408199
KEGGirno:408199
UCSCiRGD:1303193 rat

Similar proteinsi

Entry informationi

Entry nameiSUCR1_RAT
AccessioniPrimary (citable) accession number: Q6IYF9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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