Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Septin-8-B

Gene

sept8-b

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei104GTP; via amide nitrogenBy similarity1
Binding sitei239GTP; via amide nitrogen and carbonyl oxygenBy similarity1
Binding sitei254GTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi49 – 56GTPBy similarity8
Nucleotide bindingi185 – 193GTPBy similarity9

GO - Molecular functioni

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Septin-8-B
Gene namesi
Name:sept8-b
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6256297 sept8

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003632321 – 427Septin-8-BAdd BLAST427

Proteomic databases

PRIDEiQ6IRQ5

Structurei

3D structure databases

ProteinModelPortaliQ6IRQ5
SMRiQ6IRQ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 305Septin-type GPROSITE-ProRule annotationAdd BLAST267

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni49 – 56G1 motifPROSITE-ProRule annotation8
Regioni101 – 104G3 motifPROSITE-ProRule annotation4
Regioni184 – 187G4 motifPROSITE-ProRule annotation4

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili320 – 407Sequence analysisAdd BLAST88

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOVERGENiHBG065093
KOiK16939

Family and domain databases

CDDicd01850 CDC_Septin, 1 hit
InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
IPR030646 SEPT8
IPR016491 Septin
PANTHERiPTHR18884:SF54 PTHR18884:SF54, 1 hit
PfamiView protein in Pfam
PF00735 Septin, 1 hit
PIRSFiPIRSF006698 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IRQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATDVERAS NEEKRSLALS GHVGFDSLPD QLVGKSVTQG FCFNILCVGE
60 70 80 90 100
TGIGKSTLMN TLFNTTFETE EASHYENGVR LRPRTYELQE SNVHLKLTIV
110 120 130 140 150
DTVGFGDQIN KDDSYRSVVD YIDTQFETYL QEELKIRRSL FNYHDSRIHV
160 170 180 190 200
CLYFITPTGH SLKSLDLVAM KKLDSKVNII PIIAKADTIS KSELHKFKIK
210 220 230 240 250
IMSELVSNGV QIYQFPTDDD AVAEINSVMN AHLPFAVVGS TEEVKVGNKL
260 270 280 290 300
VRARQYPWGV VQVENESHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350
CKLEEMGFKD NDPDTQPFSL QETYEAKRKE FLSELQKKEE EMRQMFVNKV
360 370 380 390 400
KETESELKER ERELQEKFMQ LKRIHQEESK KVEDKRRDLE EEMNAFNRRK
410 420
VAMETLQSQS FQATSQQPLK KDKDRKN
Length:427
Mass (Da):49,761
Last modified:July 5, 2004 - v1
Checksum:iB0CFFF8F4799FA5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC070648 mRNA Translation: AAH70648.1
RefSeqiNP_001084958.1, NM_001091489.1
UniGeneiXl.19424

Genome annotation databases

GeneIDi432016
KEGGixla:432016

Similar proteinsi

Entry informationi

Entry nameiSEP8B_XENLA
AccessioniPrimary (citable) accession number: Q6IRQ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 5, 2004
Last modified: June 20, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health