Mafk

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity Source: Ensembl
RING-like zinc finger domain binding
Source: RGD
Inferred from physical interactionⁱ
- 17083329
transcription cofactor binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 16314513
transcription regulatory region sequence-specific DNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 16314513

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription by RNA polymerase II Source: Ensembl
nervous system development
Source: RGD
Inferred from direct assayⁱ
- 12388604
transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingSAAS annotation
Biological process	Transcription, Transcription regulationSAAS annotation

Enzyme and pathway databases

Reactomeⁱ	R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MAF bZIP transcription factor KImported Submitted name: V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian)Imported
Gene namesⁱ	Name:MafkImported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 12

Organism-specific databases

Rat genome database More...RGDⁱ	628633 Mafk

RGDⁱ

628633 Mafk

Subcellular locationⁱ

GO - Cellular component

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000001277 Expressed in 10 organ(s), highest expression level in heart

Bgeeⁱ

ENSRNOG00000001277 Expressed in 10 organ(s), highest expression level in heart

Interactionⁱ

GO - Molecular functionⁱ

RING-like zinc finger domain binding
Source: RGD
Inferred from physical interactionⁱ
- 17083329
transcription cofactor binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 16314513

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000001720

STRINGⁱ

10116.ENSRNOP00000001720

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	51 – 114	BZIPInterPro annotationAdd BLAST		64

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	69 – 110	Sequence analysisAdd BLAST		42

Sequence similaritiesⁱ

Belongs to the bZIP family.SAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410ISHX Eukaryota ENOG4111MYK LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074549
HOGENOMⁱ	HOG000045475
HOVERGENⁱ	HBG001725
KEGG Orthology (KO) More...KOⁱ	K09037
OMAⁱ	LQCFART
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0H46
TreeFamⁱ	TF325689

Family and domain databases

InterProⁱ	View protein in InterPro IPR004827 bZIP IPR004826 bZIP_Maf IPR028574 MafK IPR008917 TF_DNA-bd_sf IPR024874 Transciption_factor_Maf_fam
PANTHERⁱ	PTHR10129 PTHR10129, 1 hit PTHR10129:SF26 PTHR10129:SF26, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03131 bZIP_Maf, 1 hit
SMARTⁱ	View protein in SMART SM00338 BRLZ, 1 hit
SUPFAMⁱ	SSF47454 SSF47454, 1 hit
PROSITEⁱ	View protein in PROSITE PS50217 BZIP, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q6IRI7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTTNPKPNKT LKVKKEAGEN APVLSDDELV SMSVRELNQH LRGLTKEEVT 
        60         70         80         90        100
RLKQRRRTLK NRGYAASCRI KRVTQKEELE RQRVELQQEV EKLARENSSM 
       110        120        130        140        150
RLELDALRSK YEALQTFART VARGPVTPTK VATTSVITIV KSAELSSTSV 

PFSAAS

Length:156

Mass (Da):17,567

Last modified:July 5, 2004 - v1

Checksum:ⁱ2DA8C5DACB7EF6CB

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07035479 Genomic DNA No translation available. BC070906 mRNA Translation: AAH70906.1
NCBI Reference Sequences More...RefSeqⁱ	NP_663706.2, NM_145673.2 XP_006248977.1, XM_006248915.3
UniGeneⁱ	Rn.3818

Genome annotation databases

Ensemblⁱ	ENSRNOT00000001720; ENSRNOP00000001720; ENSRNOG00000001277
GeneIDⁱ	246760
KEGGⁱ	rno:246760

Protein	Similar proteins		Species	Score	Length	Source
Q6IRI7	Transcription factor MafK		HUMAN		156	UniRef90_O60675
Uncharacterized protein		ICTTR		156
Uncharacterized protein		MOUSE		156
Transcription factor MafK		PHACA		156
Transcription factor MafK		OPIHO		156
+58

Protein	Similar proteins		Species	Score	Length	Source
Q6IRI7	Transcription factor MafK		HUMAN		156	UniRef50_O60675
Uncharacterized protein		ICTTR		156
Uncharacterized protein		PIG		156
Uncharacterized protein		MOUSE		156
Transcription factor MafK		PHACA		156
+126

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07035479 Genomic DNA No translation available. BC070906 mRNA Translation: AAH70906.1
RefSeqⁱ	NP_663706.2, NM_145673.2 XP_006248977.1, XM_006248915.3
UniGeneⁱ	Rn.3818

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000001720

STRINGⁱ

10116.ENSRNOP00000001720

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000001720; ENSRNOP00000001720; ENSRNOG00000001277
GeneIDⁱ	246760
KEGGⁱ	rno:246760

Organism-specific databases

CTDⁱ	7975
RGDⁱ	628633 Mafk

Phylogenomic databases

eggNOGⁱ	ENOG410ISHX Eukaryota ENOG4111MYK LUCA
GeneTreeⁱ	ENSGT00550000074549
HOGENOMⁱ	HOG000045475
HOVERGENⁱ	HBG001725
KOⁱ	K09037
OMAⁱ	LQCFART
OrthoDBⁱ	EOG091G0H46
TreeFamⁱ	TF325689

Enzyme and pathway databases

Reactomeⁱ	R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Gene expression databases

Bgeeⁱ	ENSRNOG00000001277 Expressed in 10 organ(s), highest expression level in heart

Bgeeⁱ

ENSRNOG00000001277 Expressed in 10 organ(s), highest expression level in heart

Family and domain databases

InterProⁱ	View protein in InterPro IPR004827 bZIP IPR004826 bZIP_Maf IPR028574 MafK IPR008917 TF_DNA-bd_sf IPR024874 Transciption_factor_Maf_fam
PANTHERⁱ	PTHR10129 PTHR10129, 1 hit PTHR10129:SF26 PTHR10129:SF26, 1 hit
Pfamⁱ	View protein in Pfam PF03131 bZIP_Maf, 1 hit
SMARTⁱ	View protein in SMART SM00338 BRLZ, 1 hit
SUPFAMⁱ	SSF47454 SSF47454, 1 hit
PROSITEⁱ	View protein in PROSITE PS50217 BZIP, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6IRI7_RAT
Accessionⁱ	Q6IRI7Primary (citable) accession number: Q6IRI7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	September 12, 2018
	This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6IRI7 (Q6IRI7_RAT)

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MAF bZIP transcription factor K

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ