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UniProtKB - Q6IRI7 (Q6IRI7_RAT)
Protein
Submitted name:
V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian)
Gene
Mafk
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: RGD
- DNA-binding transcription factor activity Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: RGD
- RING-like zinc finger domain binding Source: RGD
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: RGD
- transcription cis-regulatory region binding Source: UniProtKB
- transcription coregulator binding Source: UniProtKB
GO - Biological processi
- negative regulation of transcription by RNA polymerase II Source: RGD
- nervous system development Source: RGD
- regulation of transcription, DNA-templated Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Enzyme and pathway databases
Reactomei | R-RNO-9707616, Heme signaling R-RNO-9708530, Regulation of BACH1 activity R-RNO-983231, Factors involved in megakaryocyte development and platelet production |
Names & Taxonomyi
Protein namesi | Submitted name: V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian)Imported |
Gene namesi | Name:MafkImported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Organism-specific databases
RGDi | 628633, Mafk |
Subcellular locationi
Nucleus
- nucleus Source: RGD
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000001277, Expressed in jejunum and 21 other tissues |
Interactioni
GO - Molecular functioni
- RING-like zinc finger domain binding Source: RGD
- transcription coregulator binding Source: UniProtKB
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000001720 |
Structurei
Family & Domainsi
Phylogenomic databases
eggNOGi | KOG4196, Eukaryota |
GeneTreei | ENSGT00940000160044 |
HOGENOMi | CLU_112948_0_0_1 |
OMAi | KSANHNS |
OrthoDBi | 1395389at2759 |
TreeFami | TF325689 |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR004826, bZIP_Maf IPR046347, bZIP_sf IPR028574, MafK IPR008917, TF_DNA-bd_sf IPR024874, Transcription_factor_Maf_fam |
PANTHERi | PTHR10129, PTHR10129, 1 hit PTHR10129:SF26, PTHR10129:SF26, 1 hit |
Pfami | View protein in Pfam PF03131, bZIP_Maf, 1 hit |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
SUPFAMi | SSF47454, SSF47454, 1 hit SSF57959, SSF57959, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6IRI7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTNPKPNKT LKVKKEAGEN APVLSDDELV SMSVRELNQH LRGLTKEEVT
60 70 80 90 100
RLKQRRRTLK NRGYAASCRI KRVTQKEELE RQRVELQQEV EKLARENSSM
110 120 130 140 150
RLELDALRSK YEALQTFART VARGPVTPTK VATTSVITIV KSAELSSTSV
PFSAAS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC070906 mRNA Translation: AAH70906.1 |
RefSeqi | NP_663706.2, NM_145673.2 XP_006248977.1, XM_006248915.3 |
Genome annotation databases
GeneIDi | 246760 |
KEGGi | rno:246760 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC070906 mRNA Translation: AAH70906.1 |
RefSeqi | NP_663706.2, NM_145673.2 XP_006248977.1, XM_006248915.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000001720 |
Genome annotation databases
GeneIDi | 246760 |
KEGGi | rno:246760 |
Organism-specific databases
CTDi | 7975 |
RGDi | 628633, Mafk |
Phylogenomic databases
eggNOGi | KOG4196, Eukaryota |
GeneTreei | ENSGT00940000160044 |
HOGENOMi | CLU_112948_0_0_1 |
OMAi | KSANHNS |
OrthoDBi | 1395389at2759 |
TreeFami | TF325689 |
Enzyme and pathway databases
Reactomei | R-RNO-9707616, Heme signaling R-RNO-9708530, Regulation of BACH1 activity R-RNO-983231, Factors involved in megakaryocyte development and platelet production |
Gene expression databases
Bgeei | ENSRNOG00000001277, Expressed in jejunum and 21 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR004826, bZIP_Maf IPR046347, bZIP_sf IPR028574, MafK IPR008917, TF_DNA-bd_sf IPR024874, Transcription_factor_Maf_fam |
PANTHERi | PTHR10129, PTHR10129, 1 hit PTHR10129:SF26, PTHR10129:SF26, 1 hit |
Pfami | View protein in Pfam PF03131, bZIP_Maf, 1 hit |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
SUPFAMi | SSF47454, SSF47454, 1 hit SSF57959, SSF57959, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6IRI7_RAT | |
Accessioni | Q6IRI7Primary (citable) accession number: Q6IRI7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | May 25, 2022 | |
This is version 144 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |