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Entry version 132 (12 Aug 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Zinc finger protein 219

Gene

Znf219

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional regulator (PubMed:20940257). Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG-3' (PubMed:20940257). Binds to the HMGN1 promoter and may repress HMGN1 expression (By similarity). Regulates SNCA expression in primary cortical neurons (By similarity). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9 (PubMed:20940257). Plays a role in chondrocyte differentiation (PubMed:20940257).By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri61 – 83C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri89 – 111C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri167 – 190C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri193 – 216C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri277 – 299C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri305 – 327C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri501 – 523C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri529 – 551C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri650 – 672C2H2-type 9Sequence analysisAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding, Repressor
Biological processDifferentiation, Transcription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 2191 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Znf2191 Publication
Synonyms:Zfp219Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1917140, Zfp219

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004425371 – 726Zinc finger protein 219Add BLAST726

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei16PhosphoserineBy similarity1
Modified residuei696PhosphoserineCombined sources1
Modified residuei699PhosphothreonineCombined sources1
Modified residuei702PhosphoserineCombined sources1
Modified residuei710PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6IQX8

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q6IQX8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6IQX8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6IQX8

PeptideAtlas

More...
PeptideAtlasi
Q6IQX8

PRoteomics IDEntifications database

More...
PRIDEi
Q6IQX8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6IQX8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6IQX8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in primary chondrocytes, heart, pancreas and testis.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in proliferating chondrocytes in the tibia at embryonic stage 15.5 dpc (at protein level). Expressed in limb buds at stage 11.5 dpc, where it colocalizes with Col2a1 and Sox9.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSMUSG00000049295, Expressed in ear vesicle and 328 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q6IQX8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q924S6, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SOX9 (via C-terminus).

1 Publication

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q6IQX8, 10 interactors

Molecular INTeraction database

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MINTi
Q6IQX8

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000126854

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6IQX8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q6IQX8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi229 – 275Pro-richPROSITE-ProRule annotationAdd BLAST47

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

C2H2-type zinc-finger domains 5 and 6 are important for the interaction with SOX9.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri61 – 83C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri89 – 111C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri167 – 190C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri193 – 216C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri277 – 299C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri305 – 327C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri501 – 523C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri529 – 551C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri650 – 672C2H2-type 9Sequence analysisAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161408

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008125_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6IQX8

Identification of Orthologs from Complete Genome Data

More...
OMAi
DASPPYV

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6IQX8

TreeFam database of animal gene trees

More...
TreeFami
TF332241

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 5 hits
PS50157, ZINC_FINGER_C2H2_2, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Q6IQX8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGSRPRILV GHLEPSPPAF DGELDLQRYS NGPGVSGTPG PGSPGMGAVG
60 70 80 90 100
WSETRAGERR FPCPVCGKRF RFNSILALHL RAHPGAQAFQ CPHCGHRAAQ
110 120 130 140 150
RALLRSHLRT HQPERPRSPA ARLLLELEER ALLREARLGR ARSSGGMQSS
160 170 180 190 200
PAAEGLARPQ VPSSSAFRCP FCKGKFRTSA ERERHLHILH RPWKCSLCSF
210 220 230 240 250
GSSQEEELLH HSLTAHGASE RPLAATSTPE PPPPPQQEPR SALEPEPEPE
260 270 280 290 300
PRPEPDREAN PAPTPAPPEE PPAPPEFRCQ VCGQSFTQSW FLKGHMRKHK
310 320 330 340 350
ASFDHACPVC GRCFKEPWFL KNHMKVHTSK LGPLRAPGPG SAPARAPQPP
360 370 380 390 400
DLSLLAYEPL GPALLLAPAP APAERREPPS LLGYLSVRAG EVRPNGEGAD
410 420 430 440 450
PGGGRSYGGF RPLPSALPNR ARRHRTEEPE EEEEVVEAEE ESWARGRSLG
460 470 480 490 500
SLTSLHPNPG EGSGQPAPAA GTQARSTATQ EENGLLVGGT RSEAGRGATG
510 520 530 540 550
KDCPFCGKSF RSAHHLKVHL RVHTGERPYK CPHCDYAGTQ SGSLKYHLQR
560 570 580 590 600
HHREQRSSAG PGPPPEPPPP SQRGSLQPQS GAKPTQASAT WVEGTASTRP
610 620 630 640 650
PSSSTGPGSR RKPASPGRTL RNGRGGEAEP LDLSLRAGPG GEAGAGGALH
660 670 680 690 700
RCLFCPFATG APELMALHLQ VHHSRRARGR RQPRADTSPT YVRAPSGETP
710 720
PSPPLEEEGS PGLSRSGEAG LGGQER
Length:726
Mass (Da):77,796
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7F0E43159B73B0F4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q4VA98Q4VA98_MOUSE
Zfp219 protein
Zfp219
681Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BQI8A0A2I3BQI8_MOUSE
Zinc finger protein 219
Zfp219
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BR43A0A2I3BR43_MOUSE
Zinc finger protein 219
Zfp219
201Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BS40A0A2I3BS40_MOUSE
Zinc finger protein 219
Zfp219
141Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BQZ2A0A2I3BQZ2_MOUSE
Zinc finger protein 219
Zfp219
109Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BPD9A0A2I3BPD9_MOUSE
Zinc finger protein 219
Zfp219
95Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BQ96A0A2I3BQ96_MOUSE
Zinc finger protein 219
Zfp219
10Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BS09A0A2I3BS09_MOUSE
Zinc finger protein 219
Zfp219
14Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti48A → Q in BAB61057 (PubMed:16141072).Curated1
Sequence conflicti274P → T in BAB61057 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK008516 mRNA Translation: BAB25714.1
AB063578 mRNA Translation: BAB61057.1
AC157572 Genomic DNA No translation available.
CH466659 Genomic DNA Translation: EDL42263.1
CH466659 Genomic DNA Translation: EDL42264.1
CH466659 Genomic DNA Translation: EDL42265.1
BC010447 mRNA Translation: AAH10447.1
BC071271 mRNA Translation: AAH71271.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS36916.1

NCBI Reference Sequences

More...
RefSeqi
NP_001240623.1, NM_001253694.1
NP_001240624.1, NM_001253695.1
NP_081524.2, NM_027248.2
XP_006519561.1, XM_006519498.3
XP_006519562.1, XM_006519499.3
XP_006519564.1, XM_006519501.3
XP_006519565.1, XM_006519502.3
XP_006519566.1, XM_006519503.2
XP_006519567.1, XM_006519504.3
XP_006519568.1, XM_006519505.1
XP_011243478.1, XM_011245176.2
XP_011243479.1, XM_011245177.1
XP_017171669.1, XM_017316180.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000067549; ENSMUSP00000068184; ENSMUSG00000049295
ENSMUST00000166169; ENSMUSP00000126854; ENSMUSG00000049295
ENSMUST00000226522; ENSMUSP00000154709; ENSMUSG00000049295

Database of genes from NCBI RefSeq genomes

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GeneIDi
69890

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:69890

UCSC genome browser

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UCSCi
uc007tnv.3, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008516 mRNA Translation: BAB25714.1
AB063578 mRNA Translation: BAB61057.1
AC157572 Genomic DNA No translation available.
CH466659 Genomic DNA Translation: EDL42263.1
CH466659 Genomic DNA Translation: EDL42264.1
CH466659 Genomic DNA Translation: EDL42265.1
BC010447 mRNA Translation: AAH10447.1
BC071271 mRNA Translation: AAH71271.1
CCDSiCCDS36916.1
RefSeqiNP_001240623.1, NM_001253694.1
NP_001240624.1, NM_001253695.1
NP_081524.2, NM_027248.2
XP_006519561.1, XM_006519498.3
XP_006519562.1, XM_006519499.3
XP_006519564.1, XM_006519501.3
XP_006519565.1, XM_006519502.3
XP_006519566.1, XM_006519503.2
XP_006519567.1, XM_006519504.3
XP_006519568.1, XM_006519505.1
XP_011243478.1, XM_011245176.2
XP_011243479.1, XM_011245177.1
XP_017171669.1, XM_017316180.1

3D structure databases

SMRiQ6IQX8
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ6IQX8, 10 interactors
MINTiQ6IQX8
STRINGi10090.ENSMUSP00000126854

PTM databases

iPTMnetiQ6IQX8
PhosphoSitePlusiQ6IQX8

Proteomic databases

EPDiQ6IQX8
jPOSTiQ6IQX8
MaxQBiQ6IQX8
PaxDbiQ6IQX8
PeptideAtlasiQ6IQX8
PRIDEiQ6IQX8

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
22098, 121 antibodies

Genome annotation databases

EnsembliENSMUST00000067549; ENSMUSP00000068184; ENSMUSG00000049295
ENSMUST00000166169; ENSMUSP00000126854; ENSMUSG00000049295
ENSMUST00000226522; ENSMUSP00000154709; ENSMUSG00000049295
GeneIDi69890
KEGGimmu:69890
UCSCiuc007tnv.3, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
69890
MGIiMGI:1917140, Zfp219

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000161408
HOGENOMiCLU_008125_1_0_1
InParanoidiQ6IQX8
OMAiDASPPYV
OrthoDBi1318335at2759
PhylomeDBiQ6IQX8
TreeFamiTF332241

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
69890, 4 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Zfp219, mouse

Protein Ontology

More...
PROi
PR:Q6IQX8
RNActiQ6IQX8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000049295, Expressed in ear vesicle and 328 other tissues
ExpressionAtlasiQ6IQX8, baseline and differential
GenevisibleiQ924S6, MM

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 9 hits
SUPFAMiSSF57667, SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 5 hits
PS50157, ZINC_FINGER_C2H2_2, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN219_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6IQX8
Secondary accession number(s): Q921W9, Q924S6, Q9CVF3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2017
Last sequence update: July 5, 2004
Last modified: August 12, 2020
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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