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UniProtKB - Q6IQ21 (ZN770_HUMAN)

Entry version 145 (12 Aug 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Zinc finger protein 770

Gene

ZNF770

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri27 – 49C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri55 – 77C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri81 – 103C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri294 – 318C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST25
Zinc fingeri475 – 497C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri503 – 525C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri625 – 647C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri653 – 675C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q6IQ21

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 770
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF770
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000198146.4

Human Gene Nomenclature Database

More...HGNCi		HGNC:26061, ZNF770

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6IQ21

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000198146

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162410336

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6IQ21, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF770

Domain mapping of disease mutations (DMDM)

More...DMDMi		74757996

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002804361 – 691Zinc finger protein 770Add BLAST691

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki11Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki112Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki121Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki146Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki262Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki420Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki437Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki683Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q6IQ21

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q6IQ21

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6IQ21

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6IQ21

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6IQ21

PeptideAtlas

More...PeptideAtlasi		Q6IQ21

PRoteomics IDEntifications database

More...PRIDEi		Q6IQ21

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		66477

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6IQ21

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6IQ21

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000198146, Expressed in upper arm skin and 225 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6IQ21, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6IQ21, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000198146, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120324, 28 interactors

Protein interaction database and analysis system

More...IntActi		Q6IQ21, 13 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000348673

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q6IQ21, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri27 – 49C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri55 – 77C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri81 – 103C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri294 – 318C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST25
Zinc fingeri475 – 497C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri503 – 525C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri625 – 647C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri653 – 675C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161963

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_44_7_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6IQ21

Identification of Orthologs from Complete Genome Data

More...OMAi		PESCPLP

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6IQ21

TreeFam database of animal gene trees

More...TreeFami		TF335560

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 11 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 11 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6IQ21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMAENNLKML KIQQCVVANK LPRNRPYVCN ICFKHFETPS KLARHYLIHT 
        60         70         80         90        100
GQKPFECDVC HKTFRQLVHL ERHQLTHSLP FKCSICQRHF KNLKTFVKHQ 
       110        120        130        140        150
QLHNETYQNN VKQVRRLLEA KQEKSMYGVY NTFTTEERWA LHPCSKSDPM 
       160        170        180        190        200
YSMKRRKNIH ACTICGKMFP SQSKLDRHVL IHTGQRPFKC VLCTKSFRQS 
       210        220        230        240        250
THLKIHQLTH SEERPFQCCF CQKGFKIQSK LLKHKQIHTR NKAFRALLLK 
       260        270        280        290        300
KRRTESRPLP NKLNANQGGF ENGEIGESEE NNPLDVHSIY IVPFQCPKCE 
       310        320        330        340        350
KCFESEQILN EHSCFAARSG KIPSRFKRSY NYKTIVKKIL AKLKRARSKK 
       360        370        380        390        400
LDNFQSEKKV FKKSFLRNCD LISGEQSSEQ TQRTFVGSLG KHGTYKTIGN 
       410        420        430        440        450
RKKKTLTLPF SWQNMGKNLK GILTTENILS IDNSVNKKDL SICGSSGEEF 
       460        470        480        490        500
FNNCEVLQCG FSVPRENIRT RHKICPCDKC EKVFPSISKL KRHYLIHTGQ 
       510        520        530        540        550
RPFGCNICGK SFRQSAHLKR HEQTHNEKSP YASLCQVEFG NFNNLSNHSG 
       560        570        580        590        600
NNVNYNASQQ CQAPGVQKYE VSESDQMSGV KAESQDFIPG STGQPCLPNV 
       610        620        630        640        650
LLESEQSNPF CSYSEHQEKN DVFLYRCSVC AKSFRSPSKL ERHYLIHAGQ 
       660        670        680        690 
KPFECSVCGK TFRQAPHWKR HQLTHFKERP QGKVVALDSV M
Length:691
Mass (Da):80,007
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1DA3E337BAC06A67
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YM59H0YM59_HUMAN
Zinc finger protein 770
ZNF770
132Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD18579 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti22P → L in BAA91274 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC071603 mRNA Translation: AAH71603.1
AK000589 mRNA Translation: BAA91274.1 Different termination.
AK131433 mRNA Translation: BAD18579.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10042.1

NCBI Reference Sequences

More...RefSeqi		NP_054825.2, NM_014106.3
XP_011520046.1, XM_011521744.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000356321; ENSP00000348673; ENSG00000198146

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54989

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54989

UCSC genome browser

More...UCSCi		uc001ziw.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC071603 mRNA Translation: AAH71603.1
AK000589 mRNA Translation: BAA91274.1 Different termination.
AK131433 mRNA Translation: BAD18579.1 Different initiation.
CCDSiCCDS10042.1
RefSeqiNP_054825.2, NM_014106.3
XP_011520046.1, XM_011521744.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120324, 28 interactors
IntActiQ6IQ21, 13 interactors
STRINGi9606.ENSP00000348673

PTM databases

iPTMnetiQ6IQ21
PhosphoSitePlusiQ6IQ21

Polymorphism and mutation databases

BioMutaiZNF770
DMDMi74757996

Proteomic databases

EPDiQ6IQ21
jPOSTiQ6IQ21
MassIVEiQ6IQ21
MaxQBiQ6IQ21
PaxDbiQ6IQ21
PeptideAtlasiQ6IQ21
PRIDEiQ6IQ21
ProteomicsDBi66477

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		9792, 18 antibodies

Genome annotation databases

EnsembliENST00000356321; ENSP00000348673; ENSG00000198146
GeneIDi54989
KEGGihsa:54989
UCSCiuc001ziw.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54989
EuPathDBiHostDB:ENSG00000198146.4

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF770
HGNCiHGNC:26061, ZNF770
HPAiENSG00000198146, Low tissue specificity
neXtProtiNX_Q6IQ21
OpenTargetsiENSG00000198146
PharmGKBiPA162410336

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000161963
HOGENOMiCLU_002678_44_7_1
InParanoidiQ6IQ21
OMAiPESCPLP
OrthoDBi1318335at2759
PhylomeDBiQ6IQ21
TreeFamiTF335560

Enzyme and pathway databases

PathwayCommonsiQ6IQ21
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		54989, 4 hits in 875 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54989
PharosiQ6IQ21, Tdark

Protein Ontology

More...PROi		PR:Q6IQ21
RNActiQ6IQ21, protein

Gene expression databases

BgeeiENSG00000198146, Expressed in upper arm skin and 225 other tissues
ExpressionAtlasiQ6IQ21, baseline and differential
GenevisibleiQ6IQ21, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 8 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 11 hits
SUPFAMiSSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 11 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN770_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6IQ21
Secondary accession number(s): Q6ZMZ6, Q9NWV2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2004
Last modified: August 12, 2020
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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