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Entry version 114 (08 May 2019)
Sequence version 2 (17 Apr 2007)
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Protein

Centriole, cilia and spindle-associated protein

Gene

CCSAP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating (By similarity).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • microtubule binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processCell cycle, Cell division, Mitosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Centriole, cilia and spindle-associated protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCSAP
Synonyms:C1orf96, CSAP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29578 CCSAP

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6IQ19

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Microtubule

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000154429

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672480

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCSAP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
145558871

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002846431 – 270Centriole, cilia and spindle-associated proteinAdd BLAST270

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6IQ19

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6IQ19

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6IQ19

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6IQ19

PeptideAtlas

More...
PeptideAtlasi
Q6IQ19

PRoteomics IDEntifications database

More...
PRIDEi
Q6IQ19

ProteomicsDB human proteome resource

More...
ProteomicsDBi
66472
66473 [Q6IQ19-2]
66474 [Q6IQ19-3]
66475 [Q6IQ19-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6IQ19

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6IQ19

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000154429 Expressed in 198 organ(s), highest expression level in placenta

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6IQ19 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA028402
HPA043443

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with microtubules; the association occurs on polyglutamylated tubulin (PubMed:22493317, PubMed:26562023).2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126011, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q6IQ19, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000284617

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q6IQ19

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi9 – 15ST]-E-Y-X(3)-Y motif 1; required for efficient microtubule binding and stabilizationBy similarity7
Motifi260 – 266ST]-E-Y-X(3)-Y motif 2; required for efficient microtubule binding and stabilizationBy similarity7

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi78 – 84Poly-Pro7

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CCSAP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IH9C Eukaryota
ENOG410Y5JR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003512

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000013103

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6IQ19

KEGG Orthology (KO)

More...
KOi
K16454

Identification of Orthologs from Complete Genome Data

More...
OMAi
RYQEPRW

Database of Orthologous Groups

More...
OrthoDBi
1131280at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6IQ19

TreeFam database of animal gene trees

More...
TreeFami
TF332378

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029774 CSAP

The PANTHER Classification System

More...
PANTHERi
PTHR31022 PTHR31022, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15748 CCSAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6IQ19-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSPGSGVKSE YMKRYQEPRW EEYGPCYREL LHYRLGRRLL EQAHAPWLWD
60 70 80 90 100
DWGPAGSSED SASSESSGAG GPAPRCAPPS PPPPVEPATQ EEAERRARGA
110 120 130 140 150
PEEQDAEAGD AEAEDAEDAA LPALPVKDVE DKPEQQTRTR ETDKSPTSTE
160 170 180 190 200
PRQQPSALFA RGNRKAVKSP QRSSSKIKEN KHPFALYGWG EKQTDTGSQK
210 220 230 240 250
THNVCASAPV HEIHESALRA KNRRQVEKRK LVAQRQRAHS VDVEKNRKMK
260 270
ASSSENPWMT EYMRCYSARA
Length:270
Mass (Da):30,216
Last modified:April 17, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA40F8593A5354EC
GO
Isoform 2 (identifier: Q6IQ19-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-114: Missing.
     115-122: DAEDAALP → MVPVFTSS

Note: No experimental confirmation available.
Show »
Length:156
Mass (Da):17,791
Checksum:iF506FBFF5767B44B
GO
Isoform 3 (identifier: Q6IQ19-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     123-129: ALPVKDV → GNAWLRT
     130-270: Missing.

Note: No experimental confirmation available.
Show »
Length:129
Mass (Da):14,091
Checksum:i80F765DDB8E2A87B
GO
Isoform 4 (identifier: Q6IQ19-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     123-140: ALPVKDVEDKPEQQTRTR → GTRPGGEREGPARRDGLL
     141-270: Missing.

Note: No experimental confirmation available.
Show »
Length:140
Mass (Da):15,168
Checksum:iEBC9727A2C513903
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti28R → G in AAH71609 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_059594123A → V. Corresponds to variant dbSNP:rs6587326Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0245821 – 114Missing in isoform 2. 1 PublicationAdd BLAST114
Alternative sequenceiVSP_024583115 – 122DAEDAALP → MVPVFTSS in isoform 2. 1 Publication8
Alternative sequenceiVSP_024584123 – 140ALPVK…QTRTR → GTRPGGEREGPARRDGLL in isoform 4. 1 PublicationAdd BLAST18
Alternative sequenceiVSP_024585123 – 129ALPVKDV → GNAWLRT in isoform 3. 1 Publication7
Alternative sequenceiVSP_024586130 – 270Missing in isoform 3. 1 PublicationAdd BLAST141
Alternative sequenceiVSP_024587141 – 270Missing in isoform 4. 1 PublicationAdd BLAST130

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK123465 mRNA Translation: BAC85619.1
AK291437 mRNA Translation: BAF84126.1
AL117350 Genomic DNA No translation available.
CH471098 Genomic DNA Translation: EAW69897.1
BC015419 mRNA Translation: AAH15419.1
BC039241 mRNA Translation: AAH39241.1
BC060777 mRNA Translation: AAH60777.1
BC071609 mRNA Translation: AAH71609.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1577.1 [Q6IQ19-1]

NCBI Reference Sequences

More...
RefSeqi
NP_660300.3, NM_145257.4 [Q6IQ19-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000284617; ENSP00000284617; ENSG00000154429 [Q6IQ19-1]
ENST00000366686; ENSP00000355647; ENSG00000154429 [Q6IQ19-2]
ENST00000366687; ENSP00000355648; ENSG00000154429 [Q6IQ19-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
126731

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:126731

UCSC genome browser

More...
UCSCi
uc001htl.4 human [Q6IQ19-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK123465 mRNA Translation: BAC85619.1
AK291437 mRNA Translation: BAF84126.1
AL117350 Genomic DNA No translation available.
CH471098 Genomic DNA Translation: EAW69897.1
BC015419 mRNA Translation: AAH15419.1
BC039241 mRNA Translation: AAH39241.1
BC060777 mRNA Translation: AAH60777.1
BC071609 mRNA Translation: AAH71609.1
CCDSiCCDS1577.1 [Q6IQ19-1]
RefSeqiNP_660300.3, NM_145257.4 [Q6IQ19-1]

3D structure databases

SMRiQ6IQ19
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126011, 1 interactor
IntActiQ6IQ19, 1 interactor
STRINGi9606.ENSP00000284617

PTM databases

iPTMnetiQ6IQ19
PhosphoSitePlusiQ6IQ19

Polymorphism and mutation databases

BioMutaiCCSAP
DMDMi145558871

Proteomic databases

EPDiQ6IQ19
jPOSTiQ6IQ19
MaxQBiQ6IQ19
PaxDbiQ6IQ19
PeptideAtlasiQ6IQ19
PRIDEiQ6IQ19
ProteomicsDBi66472
66473 [Q6IQ19-2]
66474 [Q6IQ19-3]
66475 [Q6IQ19-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000284617; ENSP00000284617; ENSG00000154429 [Q6IQ19-1]
ENST00000366686; ENSP00000355647; ENSG00000154429 [Q6IQ19-2]
ENST00000366687; ENSP00000355648; ENSG00000154429 [Q6IQ19-1]
GeneIDi126731
KEGGihsa:126731
UCSCiuc001htl.4 human [Q6IQ19-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
126731

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCSAP

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0001677
HGNCiHGNC:29578 CCSAP
HPAiHPA028402
HPA043443
neXtProtiNX_Q6IQ19
OpenTargetsiENSG00000154429
PharmGKBiPA142672480

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IH9C Eukaryota
ENOG410Y5JR LUCA
GeneTreeiENSGT00390000003512
HOGENOMiHOG000013103
InParanoidiQ6IQ19
KOiK16454
OMAiRYQEPRW
OrthoDBi1131280at2759
PhylomeDBiQ6IQ19
TreeFamiTF332378

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
126731

Protein Ontology

More...
PROi
PR:Q6IQ19

Gene expression databases

BgeeiENSG00000154429 Expressed in 198 organ(s), highest expression level in placenta
GenevisibleiQ6IQ19 HS

Family and domain databases

InterProiView protein in InterPro
IPR029774 CSAP
PANTHERiPTHR31022 PTHR31022, 1 hit
PfamiView protein in Pfam
PF15748 CCSAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCSAP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6IQ19
Secondary accession number(s): A8K5X2
, Q6P9G2, Q6ZW85, Q8IXU1, Q96BM2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: May 8, 2019
This is version 114 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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