UniProtKB - Q6IPE9 (Q6IPE9_HUMAN)
Protein
Submitted name:
MAP/microtubule affinity-regulating kinase 4
Gene
MARK4
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- protein kinase activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: MAP/microtubule affinity-regulating kinase 4ImportedSubmitted name: MARK4 proteinImported |
Gene namesi | Name:MARK4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
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Organism-specific databases
HGNCi | HGNC:13538, MARK4 |
VEuPathDBi | HostDB:ENSG00000007047.14 |
Expressioni
Gene expression databases
Bgeei | ENSG00000007047, Expressed in male germ cell and 236 other tissues |
ExpressionAtlasi | Q6IPE9, baseline and differential |
Interactioni
Binary interactionsi
Hide detailsQ6IPE9
Protein-protein interaction databases
IntActi | Q6IPE9, 8 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 97 | Protein kinaseInterPro annotationAdd BLAST | 97 |
Phylogenomic databases
GeneTreei | ENSGT00940000159555 |
HOGENOMi | CLU_000288_63_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
Q6IPE9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSRTVLAPG NDRNSDTAEN LLLDAEANIK IADFGFSNEF TLGSKLDTFC
60 70 80 90
GSPPYAAPEL FQGKKYDGPE VDIWSLGVIL YTLVSGSLPF DGHNLKR
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ96L34 | MARK4_HUMAN | MAP/microtubule affinity-regulating... | MARK4 KIAA1860, MARKL1 | 752 | Annotation score: | ||
Q96GZ3 | Q96GZ3_HUMAN | Non-specific serine/threonine prote... | MARK4 | 79 | Annotation score: | ||
K7EKG8 | K7EKG8_HUMAN | MAP/microtubule affinity-regulating... | MARK4 | 74 | Annotation score: | ||
K7EN95 | K7EN95_HUMAN | MAP/microtubule affinity-regulating... | MARK4 | 48 | Annotation score: | ||
K7EK17 | K7EK17_HUMAN | MAP/microtubule affinity-regulating... | MARK4 | 62 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005581 Genomic DNA No translation available. AC005757 Genomic DNA No translation available. AC005779 Genomic DNA No translation available. AC005781 Genomic DNA No translation available. AC006126 Genomic DNA No translation available. AC011489 Genomic DNA No translation available. AC093064 Genomic DNA No translation available. BC071948 mRNA Translation: AAH71948.1 |
Genome annotation databases
Ensembli | ENST00000592762; ENSP00000466702; ENSG00000007047 ENST00000620044; ENSP00000480702; ENSG00000007047 |
UCSCi | uc060zxb.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005581 Genomic DNA No translation available. AC005757 Genomic DNA No translation available. AC005779 Genomic DNA No translation available. AC005781 Genomic DNA No translation available. AC006126 Genomic DNA No translation available. AC011489 Genomic DNA No translation available. AC093064 Genomic DNA No translation available. BC071948 mRNA Translation: AAH71948.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q6IPE9, 8 interactors |
Proteomic databases
MaxQBi | Q6IPE9 |
PRIDEi | Q6IPE9 |
Protocols and materials databases
Antibodypediai | 31285, 378 antibodies |
Genome annotation databases
Ensembli | ENST00000592762; ENSP00000466702; ENSG00000007047 ENST00000620044; ENSP00000480702; ENSG00000007047 |
UCSCi | uc060zxb.1, human |
Organism-specific databases
HGNCi | HGNC:13538, MARK4 |
OpenTargetsi | ENSG00000007047 |
VEuPathDBi | HostDB:ENSG00000007047.14 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159555 |
HOGENOMi | CLU_000288_63_0_1 |
Miscellaneous databases
ChiTaRSi | MARK4, human |
Gene expression databases
Bgeei | ENSG00000007047, Expressed in male germ cell and 236 other tissues |
ExpressionAtlasi | Q6IPE9, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6IPE9_HUMAN | |
Accessioni | Q6IPE9Primary (citable) accession number: Q6IPE9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 133 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |