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Protein

Histone H2A

Gene

h2afj

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H2AUniRule annotation
Gene namesi
Name:h2afjImported
Synonyms:MGC83508Imported
ORF Names:XELAEV_18024002mgImported, XELAEV_18025911mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componentsi: Chromosome 4l, Chromosome 4s

Organism-specific databases

XenbaseiXB-GENE-5838633 h2afj

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotationSAAS annotation, NucleusUniRule annotationSAAS annotation

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotationSAAS annotation

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 89HistoneInterPro annotationAdd BLAST85
Domaini92 – 126Histone_H2A_CInterPro annotationAdd BLAST35

Sequence similaritiesi

Belongs to the histone H2A family.UniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG009342
KOiK11251

Family and domain databases

CDDicd00074 H2A, 1 hit
Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR002119 Histone_H2A
IPR007125 Histone_H2A/H2B/H3
IPR032454 Histone_H2A_C
IPR032458 Histone_H2A_CS
PfamiView protein in Pfam
PF00125 Histone, 1 hit
PF16211 Histone_H2A_C, 1 hit
PRINTSiPR00620 HISTONEH2A
SMARTiView protein in SMART
SM00414 H2A, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS00046 HISTONE_H2A, 1 hit

Sequencei

Sequence statusi: Complete.

Q6INC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRGKSGGK ARAKAKSRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV
60 70 80 90 100
YLAAVLEYLS AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGG
110 120
VTIAQGGVLP NIQAVLLPKK TQTSKK
Length:126
Mass (Da):13,521
Last modified:July 5, 2004 - v1
Checksum:iA3FE4ED3B0AEA4AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC072354 mRNA Translation: AAH72354.1
BC092032 mRNA Translation: AAH92032.1
CM004473 Genomic DNA Translation: OCT83371.1
CM004472 Genomic DNA Translation: OCT85833.1
RefSeqiNP_001085177.1, NM_001091708.1
XP_018112152.1, XM_018256663.1
XP_018112153.1, XM_018256664.1
XP_018112154.1, XM_018256665.1
XP_018116885.1, XM_018261396.1
UniGeneiXl.7144

Genome annotation databases

GeneIDi108715878
432260
KEGGixla:108715878
xla:432260

Similar proteinsi

Entry informationi

Entry nameiQ6INC9_XENLA
AccessioniPrimary (citable) accession number: Q6INC9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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