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Protein
Submitted name:

Sp7 transcription factor

Gene

Sp7

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Sp7 transcription factorImported
Submitted name:
Specificity protein 7 alphaImported
Gene namesi
Name:Sp7Imported
ORF Names:rCG_50652Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi631377 Sp7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ6IMK2

Expressioni

Gene expression databases

BgeeiENSRNOG00000014082 Expressed in 1 organ(s), highest expression level in brain
ExpressionAtlasiQ6IMK2 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ6IMK2, 1 interactor
MINTiQ6IMK2
STRINGi10116.ENSRNOP00000018828

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini291 – 320C2H2-typeInterPro annotationAdd BLAST30
Domaini321 – 350C2H2-typeInterPro annotationAdd BLAST30
Domaini351 – 378C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118984
HOGENOMiHOG000231067
HOVERGENiHBG036899
OMAiEEAHYGS
OrthoDBiEOG091G0HX6
TreeFamiTF350150

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6IMK2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSLLEEEA HYGSSPLAML TAACSKFGGS SPLRDSTALG KGGTKKPYTD
60 70 80 90 100
LSAPKTMGDA YPAPFSSTNG LLSPAGSPPA PASGYANDYP PFPHSFPGPT
110 120 130 140 150
GAQDPGLLVP KGHSSSDCLP SVYTSLDMSH PYGSWYKAGI HAGISPGPGN
160 170 180 190 200
TPTPWWDMHP GGNWLGGGQG QGDGLQGTLS TGPAQPPLNP QLPTYPSDFA
210 220 230 240 250
PLNPAPYPAP HLLQPGPQHV LPQDVYKPKA VGNSGQLEGS GAGKPPRGAG
260 270 280 290 300
TGGSGGYAGS GAGRSTCDCP NCQELERLGA AAAGLRKKPI HSCHIPGCGK
310 320 330 340 350
VYGKASHLKA HLRWHTGERP FVCNWLFCGK RFTRSDELER HVRTHTREKK
360 370 380 390 400
FTCLLCSKRF TRSDHLSKHQ RTHGEPGPGP PPSGPKELGE GRSVGEEEAN
410 420
QPPRSSTSPA PPEKAPGGSP EQSNLLEI
Length:428
Mass (Da):44,650
Last modified:July 5, 2004 - v1
Checksum:iA1FC883E689D79A6
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6IMK1Q6IMK1_RAT
Sp7 transcription factor
Sp7
410Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097309 Genomic DNA No translation available.
BK001412 mRNA Translation: DAA01455.1
CH474035 Genomic DNA Translation: EDL86842.1
RefSeqiNP_852039.2, NM_181374.2
XP_008763928.1, XM_008765706.2
XP_017450280.1, XM_017594791.1
UniGeneiRn.92200

Genome annotation databases

EnsembliENSRNOT00000018828; ENSRNOP00000018828; ENSRNOG00000014082
GeneIDi300260

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097309 Genomic DNA No translation available.
BK001412 mRNA Translation: DAA01455.1
CH474035 Genomic DNA Translation: EDL86842.1
RefSeqiNP_852039.2, NM_181374.2
XP_008763928.1, XM_008765706.2
XP_017450280.1, XM_017594791.1
UniGeneiRn.92200

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6IMK2, 1 interactor
MINTiQ6IMK2
STRINGi10116.ENSRNOP00000018828

Proteomic databases

PRIDEiQ6IMK2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000018828; ENSRNOP00000018828; ENSRNOG00000014082
GeneIDi300260

Organism-specific databases

CTDi121340
RGDi631377 Sp7

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118984
HOGENOMiHOG000231067
HOVERGENiHBG036899
OMAiEEAHYGS
OrthoDBiEOG091G0HX6
TreeFamiTF350150

Gene expression databases

BgeeiENSRNOG00000014082 Expressed in 1 organ(s), highest expression level in brain
ExpressionAtlasiQ6IMK2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IMK2_RAT
AccessioniPrimary (citable) accession number: Q6IMK2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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