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UniProtKB - Q6ICG8 (WBP2L_HUMAN)

Entry version 121 (02 Jun 2021)
Sequence version 1 (05 Jul 2004)
Previous versions | rss
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Protein

Postacrosomal sheath WW domain-binding protein

Gene

WBP2NL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in meotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processMeiosis

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q6ICG8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Postacrosomal sheath WW domain-binding protein
Alternative name(s):
WW domain-binding protein 2-like
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WBP2NL
Synonyms:PAWP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28389, WBP2NL

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		610981, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6ICG8

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000183066.14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		164684

Open Targets

More...OpenTargetsi		ENSG00000183066

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA145147710

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6ICG8, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		WBP2NL

Domain mapping of disease mutations (DMDM)

More...DMDMi		74757724

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002891271 – 309Postacrosomal sheath WW domain-binding proteinAdd BLAST309

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6ICG8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6ICG8

PeptideAtlas

More...PeptideAtlasi		Q6ICG8

PRoteomics IDEntifications database

More...PRIDEi		Q6ICG8

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		66390

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6ICG8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6ICG8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000183066, Expressed in right testis and 123 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6ICG8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6ICG8, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000183066, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127900, 6 interactors

Protein interaction database and analysis system

More...IntActi		Q6ICG8, 8 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000332983

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q6ICG8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q6ICG8

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini45 – 87GRAMAdd BLAST43
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati175 – 18117
Repeati182 – 18827
Repeati189 – 19537
Repeati217 – 22347
Repeati224 – 23057
Repeati231 – 23767
Repeati238 – 24477
Repeati245 – 25187
Repeati252 – 25897
Repeati259 – 265107

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni175 – 26510 X 7 AA tandem repeat of Y-G-X-P-P-X-GAdd BLAST91
Regioni251 – 309DisorderedSequence analysisAdd BLAST59

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi186 – 189PPxY motif4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi281 – 309Polar residuesSequence analysisAdd BLAST29

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3294, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00530000063718

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6ICG8

Identification of Orthologs from Complete Genome Data

More...OMAi		CTIEQPI

Database of Orthologous Groups

More...OrthoDBi		1513129at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6ICG8

TreeFam database of animal gene trees

More...TreeFami		TF314141

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004182, GRAM
IPR033597, WBP2NL

The PANTHER Classification System

More...PANTHERi		PTHR31606:SF2, PTHR31606:SF2, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02893, GRAM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q6ICG8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVNQSHTEN RRGALIPNGE SLLKRSPNVE LSFPQRSEGS NVFSGRKTGT 
        60         70         80         90        100
LFLTSYRVIF ITSCSISDPM LSFMMPFDLM TNLTVEQPVF AANFIKGTIQ 
       110        120        130        140        150
AAPYGGWEGQ ATFKLVFRNG DAIEFAQLMV KAASAAARGF PLRTLNDWFS 
       160        170        180        190        200
SMGIYVITGE GNMCTPQMPC SVIVYGAPPA GYGAPPPGYG APPAGYGAQP 
       210        220        230        240        250
VGNEGPPVGY RASPVRYGAP PLGYGAPPAG YGAPPLGYGA PPLGYGTPPL 
       260        270        280        290        300
GYGAPPLGYG APPAGNEGPP AGYRASPAGS GARPQESTAA QAPENEASLP 

SASSSQVHS
Length:309
Mass (Da):31,909
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD09202E9A951DF48
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WDR4F8WDR4_HUMAN
Postacrosomal sheath WW domain-bind...
WBP2NL
273Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H7L2F5H7L2_HUMAN
Postacrosomal sheath WW domain-bind...
WBP2NL
235Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WCF8F8WCF8_HUMAN
Postacrosomal sheath WW domain-bind...
WBP2NL
83Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH22549 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti136A → V in AAQ02873 (PubMed:17289678).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0325785Q → E. Corresponds to variant dbSNP:rs17002790Ensembl.1
Natural variantiVAR_032579121D → G1 PublicationCorresponds to variant dbSNP:rs133335Ensembl.1
Natural variantiVAR_032580170C → F. Corresponds to variant dbSNP:rs17002802Ensembl.1
Natural variantiVAR_032581285Q → H1 PublicationCorresponds to variant dbSNP:rs2301521Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CR456400 mRNA Translation: CAG30286.1
AK128138 mRNA Translation: BAG54636.1
Z99716 Genomic DNA No translation available.
BC022546 mRNA Translation: AAH22546.1
BC022549 mRNA Translation: AAH22549.1 Frameshift.
AF393575 mRNA Translation: AAQ02873.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14029.1

NCBI Reference Sequences

More...RefSeqi		NP_689826.2, NM_152613.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000328823; ENSP00000332983; ENSG00000183066
ENST00000329620; ENSP00000328800; ENSG00000183066
ENST00000436265; ENSP00000401002; ENSG00000183066

Database of genes from NCBI RefSeq genomes

More...GeneIDi		164684

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:164684

UCSC genome browser

More...UCSCi		uc003bbt.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456400 mRNA Translation: CAG30286.1
AK128138 mRNA Translation: BAG54636.1
Z99716 Genomic DNA No translation available.
BC022546 mRNA Translation: AAH22546.1
BC022549 mRNA Translation: AAH22549.1 Frameshift.
AF393575 mRNA Translation: AAQ02873.1
CCDSiCCDS14029.1
RefSeqiNP_689826.2, NM_152613.2

3D structure databases

SMRiQ6ICG8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127900, 6 interactors
IntActiQ6ICG8, 8 interactors
STRINGi9606.ENSP00000332983

PTM databases

iPTMnetiQ6ICG8
PhosphoSitePlusiQ6ICG8

Genetic variation databases

BioMutaiWBP2NL
DMDMi74757724

Proteomic databases

MassIVEiQ6ICG8
PaxDbiQ6ICG8
PeptideAtlasiQ6ICG8
PRIDEiQ6ICG8
ProteomicsDBi66390

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		27190, 96 antibodies

The DNASU plasmid repository

More...DNASUi		164684

Genome annotation databases

EnsembliENST00000328823; ENSP00000332983; ENSG00000183066
ENST00000329620; ENSP00000328800; ENSG00000183066
ENST00000436265; ENSP00000401002; ENSG00000183066
GeneIDi164684
KEGGihsa:164684
UCSCiuc003bbt.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		164684
DisGeNETi164684

GeneCards: human genes, protein and diseases

More...GeneCardsi		WBP2NL
HGNCiHGNC:28389, WBP2NL
HPAiENSG00000183066, Tissue enriched (testis)
MIMi610981, gene
neXtProtiNX_Q6ICG8
OpenTargetsiENSG00000183066
PharmGKBiPA145147710
VEuPathDBiHostDB:ENSG00000183066.14

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3294, Eukaryota
GeneTreeiENSGT00530000063718
InParanoidiQ6ICG8
OMAiCTIEQPI
OrthoDBi1513129at2759
PhylomeDBiQ6ICG8
TreeFamiTF314141

Enzyme and pathway databases

PathwayCommonsiQ6ICG8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		164684, 9 hits in 984 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		WBP2NL, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		164684
PharosiQ6ICG8, Tbio

Protein Ontology

More...PROi		PR:Q6ICG8
RNActiQ6ICG8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000183066, Expressed in right testis and 123 other tissues
ExpressionAtlasiQ6ICG8, baseline and differential
GenevisibleiQ6ICG8, HS

Family and domain databases

InterProiView protein in InterPro
IPR004182, GRAM
IPR033597, WBP2NL
PANTHERiPTHR31606:SF2, PTHR31606:SF2, 2 hits
PfamiView protein in Pfam
PF02893, GRAM, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWBP2L_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ICG8
Secondary accession number(s): A3KFF7
, A8MSG5, B3KXX4, Q8TBF0, Q8TBF3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: July 5, 2004
Last modified: June 2, 2021
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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