TCEA2

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	257 – 297	TFIIS-typePROSITE-ProRule annotationAdd BLAST		41

GO - Molecular functionⁱ

translation elongation factor activity Source: UniProtKB-KW
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

positive regulation of transcription by RNA polymerase II Source: Ensembl
transcription, DNA-templated Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Elongation factorImported
Biological process	Protein biosynthesis
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: TCEA2 proteinImported Submitted name: Transcription elongation factor A (SII), 2, isoform CRA_aImported
Gene namesⁱ	Name:TCEA2Imported ORF Names:hCG_2021465Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000171703.16

EuPathDBⁱ

HostDB:ENSG00000171703.16

Keywords - Cellular componentⁱ

NucleusPROSITE-ProRule annotation

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA36373

PharmGKBⁱ

PA36373

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000171703 Expressed in 209 organ(s), highest expression level in right hemisphere of cerebellum

Bgeeⁱ

ENSG00000171703 Expressed in 209 organ(s), highest expression level in right hemisphere of cerebellum

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	6 – 83	TFIIS N-terminalInterPro annotationAdd BLAST	78
Domainⁱ	138 – 254	TFIIS centralInterPro annotationAdd BLAST	117
Domainⁱ	257 – 297	TFIIS-typeInterPro annotationAdd BLAST	41

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	257 – 297	TFIIS-typePROSITE-ProRule annotationAdd BLAST		41

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1105 Eukaryota COG1594 LUCA
HOVERGENⁱ	HBG055022
KEGG Orthology (KO) More...KOⁱ	K03145
OMAⁱ	CEHIAAQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G10EJ

Family and domain databases

Gene3Dⁱ	1.10.472.30, 1 hit 1.20.930.10, 1 hit
InterProⁱ	View protein in InterPro IPR035100 TF_IIS-typ IPR003617 TFIIS/CRSP70_N_sub IPR035441 TFIIS/LEDGF_dom_sf IPR003618 TFIIS_cen_dom IPR036575 TFIIS_cen_dom_sf IPR017923 TFIIS_N IPR006289 TFSII IPR001222 Znf_TFIIS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08711 Med26, 1 hit PF01096 TFIIS_C, 1 hit PF07500 TFIIS_M, 1 hit
PIRSFⁱ	PIRSF006704 TF_IIS, 1 hit
SMARTⁱ	View protein in SMART SM00510 TFS2M, 1 hit SM00509 TFS2N, 1 hit SM00440 ZnF_C2C2, 1 hit
SUPFAMⁱ	SSF46942 SSF46942, 1 hit SSF47676 SSF47676, 1 hit
TIGRFAMsⁱ	TIGR01385 TFSII, 1 hit
PROSITEⁱ	View protein in PROSITE PS51321 TFIIS_CENTRAL, 1 hit PS51319 TFIIS_N, 1 hit PS00466 ZF_TFIIS_1, 1 hit PS51133 ZF_TFIIS_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q6IB64-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MMGKEEEIAR IARRLDKMVT KKSAEGAMDL LRELKAMPIT LHLLQSTRVG 
        60         70         80         90        100
MSVNALRKQS SDEEVIALAK SLIKSWKKLL DASDAKARER GRGMPLPTSS 
       110        120        130        140        150
RDASEAPDPS RKRPELPRAP STPRITTFPP VPVTCDAVRN KCREMLTAAL 
       160        170        180        190        200
QTDHDHVAIG ADCERLSAQI EECIFRDVGN TDMKYKNRVR SRISNLKDAK 
       210        220        230        240        250
NPDLRRNVLC GAITPQQIAV MTSEEMASDE LKEIRKAMTK EAIREHQMAR 
       260        270        280        290 
TGGTQTDLFT CGKCRKKNCT YTQVQTRSSD EPMTTFVVCN ECGNRWKFC

Length:299

Mass (Da):33,601

Last modified:May 10, 2005 - v1

Checksum:ⁱFF0EAE8EDC7BCBE9

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CR456940 mRNA Translation: CAG33221.1 CH471077 Genomic DNA Translation: EAW75168.1
NCBI Reference Sequences More...RefSeqⁱ	NP_003186.1, NM_003195.5
UniGeneⁱ	Hs.505004 Hs.736326

Genome annotation databases

GeneIDⁱ	6919
KEGGⁱ	hsa:6919
UCSC genome browser More...UCSCⁱ	uc061yqu.1 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q6IB64	Transcription elongation factor A protein 2	)	HUMAN		299	UniRef100_Q15560
TCEA2 isoform 2		PANTR		272
Uncharacterized protein		PANPA		299
Isoform 2 of Transcription elongation factor A protein 2		HUMAN		272
TCEA2 isoform 3		PANTR		299
+1

Protein	Similar proteins		Species	Score	Length	Source
Q6IB64	Transcription elongation factor A protein 2	)	HUMAN		299	UniRef90_Q15560
TCEA2 isoform 2		PANTR		272
Uncharacterized protein		PANPA		299
Isoform 2 of Transcription elongation factor A protein 2		HUMAN		272
TCEA2 isoform 3		PANTR		299
+10

Protein	Similar proteins		Species	Score	Length	Source
Q6IB64	Transcription elongation factor A protein 2	)	HUMAN		299	UniRef50_Q15560
TCEA2 isoform 2		PANTR		272
Uncharacterized protein		PANPA		299
Uncharacterized protein		AOTNA		475
transcription elongation factor A protein 2 isoform X1		TURTR		411
+42

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CR456940 mRNA Translation: CAG33221.1 CH471077 Genomic DNA Translation: EAW75168.1
RefSeqⁱ	NP_003186.1, NM_003195.5
UniGeneⁱ	Hs.505004 Hs.736326

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6919
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	6919
KEGGⁱ	hsa:6919
UCSCⁱ	uc061yqu.1 human

Organism-specific databases

CTDⁱ	6919
EuPathDBⁱ	HostDB:ENSG00000171703.16
PharmGKBⁱ	PA36373

Phylogenomic databases

eggNOGⁱ	KOG1105 Eukaryota COG1594 LUCA
HOVERGENⁱ	HBG055022
KOⁱ	K03145
OMAⁱ	CEHIAAQ
OrthoDBⁱ	EOG091G10EJ

Miscellaneous databases

GenomeRNAiⁱ	6919

GenomeRNAiⁱ

6919

Gene expression databases

Bgeeⁱ	ENSG00000171703 Expressed in 209 organ(s), highest expression level in right hemisphere of cerebellum

Bgeeⁱ

ENSG00000171703 Expressed in 209 organ(s), highest expression level in right hemisphere of cerebellum

Family and domain databases

Gene3Dⁱ	1.10.472.30, 1 hit 1.20.930.10, 1 hit
InterProⁱ	View protein in InterPro IPR035100 TF_IIS-typ IPR003617 TFIIS/CRSP70_N_sub IPR035441 TFIIS/LEDGF_dom_sf IPR003618 TFIIS_cen_dom IPR036575 TFIIS_cen_dom_sf IPR017923 TFIIS_N IPR006289 TFSII IPR001222 Znf_TFIIS
Pfamⁱ	View protein in Pfam PF08711 Med26, 1 hit PF01096 TFIIS_C, 1 hit PF07500 TFIIS_M, 1 hit
PIRSFⁱ	PIRSF006704 TF_IIS, 1 hit
SMARTⁱ	View protein in SMART SM00510 TFS2M, 1 hit SM00509 TFS2N, 1 hit SM00440 ZnF_C2C2, 1 hit
SUPFAMⁱ	SSF46942 SSF46942, 1 hit SSF47676 SSF47676, 1 hit
TIGRFAMsⁱ	TIGR01385 TFSII, 1 hit
PROSITEⁱ	View protein in PROSITE PS51321 TFIIS_CENTRAL, 1 hit PS51319 TFIIS_N, 1 hit PS00466 ZF_TFIIS_1, 1 hit PS51133 ZF_TFIIS_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6IB64_HUMAN
Accessionⁱ	Q6IB64Primary (citable) accession number: Q6IB64
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 10, 2005
	Last sequence update:	May 10, 2005
	Last modified:	November 7, 2018
	This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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UniProtKB - Q6IB64 (Q6IB64_HUMAN)

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TCEA2 protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Expressionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ