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UniProtKB - Q6IB42 (Q6IB42_HUMAN)
Protein
Submitted name:
MYL2 protein
Gene
MYL2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- calcium ion binding Source: InterPro
Keywordsi
Ligand | Metal-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: MYL2 proteinImportedSubmitted name: Myosin, light polypeptide 2, regulatory, cardiac, slow, isoform CRA_aImportedSubmitted name: cDNA, FLJ92288, highly similar to Homo sapiens myosin, light polypeptide 2, regulatory, cardiac, slow (MYL2), mRNAImported |
Gene namesi | Name:MYL2Imported ORF Names:hCG_40212Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000111245 |
Expressioni
Gene expression databases
Bgeei | ENSG00000111245, Expressed in myocardium and 131 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 24 – 59 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 94 – 129 | EF-handInterPro annotationAdd BLAST | 36 |
Phylogenomic databases
HOGENOMi | CLU_061288_9_0_1 |
OMAi | ARNAMSK |
OrthoDBi | 1435392at2759 |
Family and domain databases
CDDi | cd00051, EFh, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom |
Pfami | View protein in Pfam PF00036, EF-hand_1, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 3 hits |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 2 hits |
i Sequence
Sequence statusi: Complete.
Q6IB42-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR
60 70 80 90 100
DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL
110 120 130 140 150
NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL
160
DYKNLVHIIT HGEEKD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK312013 mRNA Translation: BAG34951.1 CR456962 mRNA Translation: CAG33243.1 CR541957 mRNA Translation: CAG46755.1 CH471054 Genomic DNA Translation: EAW97943.1 |
RefSeqi | NP_000423.2, NM_000432.3 |
Genome annotation databases
GeneIDi | 4633 |
KEGGi | hsa:4633 |
MANE-Selecti | ENST00000228841.15; ENSP00000228841.8; NM_000432.4; NP_000423.2 |
UCSCi | uc001try.5, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK312013 mRNA Translation: BAG34951.1 CR456962 mRNA Translation: CAG33243.1 CR541957 mRNA Translation: CAG46755.1 CH471054 Genomic DNA Translation: EAW97943.1 |
RefSeqi | NP_000423.2, NM_000432.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 31071, 409 antibodies from 38 providers |
DNASUi | 4633 |
Genome annotation databases
GeneIDi | 4633 |
KEGGi | hsa:4633 |
MANE-Selecti | ENST00000228841.15; ENSP00000228841.8; NM_000432.4; NP_000423.2 |
UCSCi | uc001try.5, human |
Organism-specific databases
CTDi | 4633 |
PharmGKBi | PA31380 |
VEuPathDBi | HostDB:ENSG00000111245 |
Phylogenomic databases
HOGENOMi | CLU_061288_9_0_1 |
OMAi | ARNAMSK |
OrthoDBi | 1435392at2759 |
Miscellaneous databases
BioGRID-ORCSi | 4633, 10 hits in 1069 CRISPR screens |
ChiTaRSi | MYL2, human |
GenomeRNAii | 4633 |
Gene expression databases
Bgeei | ENSG00000111245, Expressed in myocardium and 131 other tissues |
Family and domain databases
CDDi | cd00051, EFh, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom |
Pfami | View protein in Pfam PF00036, EF-hand_1, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 3 hits |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6IB42_HUMAN | |
Accessioni | Q6IB42Primary (citable) accession number: Q6IB42 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | May 25, 2022 | |
This is version 144 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |