Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

RNASE6 protein

Gene

RNASE6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Submitted name:
RNASE6 proteinImported
Submitted name:
Ribonuclease A D1Imported
Submitted name:
Ribonuclease, RNase A family, k6, isoform CRA_aImported
Submitted name:
Testicular tissue protein Li 166Imported
Submitted name:
cDNA, FLJ94144, Homo sapiens ribonuclease, RNase A family, k6 (RNASE6), mRNAImported
Gene namesi
Name:RNASE6Imported
Synonyms:RAD1Imported
ORF Names:hCG_1640892Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000169413.2

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34416

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_501420594424 – 150UniRule annotationAdd BLAST127

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000169413 Expressed in 168 organ(s), highest expression level in leukocyte

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 150RNAse_PcInterPro annotationAdd BLAST124

Sequence similaritiesi

Belongs to the pancreatic ribonuclease family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410IYEW Eukaryota
ENOG4111D8Q LUCA
HOVERGENiHBG008396
KOiK01172
OMAiHWFEIQH
OrthoDBiEOG091G0U42

Family and domain databases

Gene3Di3.10.130.10, 1 hit
InterProiView protein in InterPro
IPR001427 RNaseA
IPR036816 RNaseA-like_dom_sf
IPR023411 RNaseA_AS
IPR023412 RNaseA_domain
PANTHERiPTHR11437 PTHR11437, 1 hit
PfamiView protein in Pfam
PF00074 RnaseA, 1 hit
PRINTSiPR00794 RIBONUCLEASE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000535 RNaseA, 1 hit
SMARTiView protein in SMART
SM00092 RNAse_Pc, 1 hit
SUPFAMiSSF54076 SSF54076, 1 hit
PROSITEiView protein in PROSITE
PS00127 RNASE_PANCREATIC, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IB39-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLCFPLLLL LLVLWGPVCP LHAWPKRLTK AHWFEIQHIQ PSPLQCNRAM
60 70 80 90 100
SGINNYTQHC KHQNTFLHDS FQNVAAVCDL LSIVCKNRRH NCHQSSKPVN
110 120 130 140 150
MTDCRLTSGK YPQCRYSAAA QYKFFIVACD PPQKSDPPYK LVPVHLDSIL
Length:150
Mass (Da):17,196
Last modified:May 10, 2005 - v1
Checksum:i4C1F722066BCC13A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM005479 mRNA Translation: AEE61077.1
AK313580 mRNA Translation: BAG36350.1
CR456965 mRNA Translation: CAG33246.1
HG328838 Genomic DNA Translation: CDG31914.1
CH471078 Genomic DNA Translation: EAW66440.1
CH471078 Genomic DNA Translation: EAW66441.1
CH471078 Genomic DNA Translation: EAW66442.1
RefSeqiNP_005606.1, NM_005615.4
XP_016877055.1, XM_017021566.1
XP_016877056.1, XM_017021567.1
UniGeneiHs.23262

Genome annotation databases

GeneIDi6039
KEGGihsa:6039

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM005479 mRNA Translation: AEE61077.1
AK313580 mRNA Translation: BAG36350.1
CR456965 mRNA Translation: CAG33246.1
HG328838 Genomic DNA Translation: CDG31914.1
CH471078 Genomic DNA Translation: EAW66440.1
CH471078 Genomic DNA Translation: EAW66441.1
CH471078 Genomic DNA Translation: EAW66442.1
RefSeqiNP_005606.1, NM_005615.4
XP_016877055.1, XM_017021566.1
XP_016877056.1, XM_017021567.1
UniGeneiHs.23262

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi6039
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6039
KEGGihsa:6039

Organism-specific databases

CTDi6039
EuPathDBiHostDB:ENSG00000169413.2
PharmGKBiPA34416

Phylogenomic databases

eggNOGiENOG410IYEW Eukaryota
ENOG4111D8Q LUCA
HOVERGENiHBG008396
KOiK01172
OMAiHWFEIQH
OrthoDBiEOG091G0U42

Miscellaneous databases

GenomeRNAii6039

Gene expression databases

BgeeiENSG00000169413 Expressed in 168 organ(s), highest expression level in leukocyte

Family and domain databases

Gene3Di3.10.130.10, 1 hit
InterProiView protein in InterPro
IPR001427 RNaseA
IPR036816 RNaseA-like_dom_sf
IPR023411 RNaseA_AS
IPR023412 RNaseA_domain
PANTHERiPTHR11437 PTHR11437, 1 hit
PfamiView protein in Pfam
PF00074 RnaseA, 1 hit
PRINTSiPR00794 RIBONUCLEASE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000535 RNaseA, 1 hit
SMARTiView protein in SMART
SM00092 RNAse_Pc, 1 hit
SUPFAMiSSF54076 SSF54076, 1 hit
PROSITEiView protein in PROSITE
PS00127 RNASE_PANCREATIC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IB39_HUMAN
AccessioniPrimary (citable) accession number: Q6IB39
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 7, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again