UniProtKB - Q6IB29 (Q6IB29_HUMAN)
Protein
Submitted name:
EBNA1 binding protein 2
Gene
EBNA1BP2
Organism
Homo sapiens (Human)
Status
Functioni
Required for the processing of the 27S pre-rRNA.ARBA annotation
GO - Biological processi
- ribosome biogenesis Source: UniProtKB-KW
Keywordsi
Biological process | Ribosome biogenesisARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: EBNA1 binding protein 2ImportedSubmitted name: EBNA1 binding protein 2 variantImportedSubmitted name: EBNA1 binding protein 2, isoform CRA_aImportedSubmitted name: EBNA1BP2 proteinImported |
Gene namesi | Name:EBNA1BP2Imported ORF Names:hCG_2031782Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000117395.10 |
Subcellular locationi
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000117395, Expressed in right lobe of liver and 236 other tissues |
ExpressionAtlasi | Q6IB29, baseline and differential |
Interactioni
Binary interactionsi
Q6IB29
With | #Exp. | IntAct |
---|---|---|
FAM9B [Q8IZU0] | 3 | EBI-10249955,EBI-10175124 |
Protein-protein interaction databases
IntActi | Q6IB29, 1 interactor |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 20 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 77 – 99 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 213 – 306 | DisorderedSequence analysisAdd BLAST | 94 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 147 – 167 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 235 – 251 | BasicSequence analysisAdd BLAST | 17 | |
Compositional biasi | 256 – 273 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 276 – 306 | BasicSequence analysisAdd BLAST | 31 |
Sequence similaritiesi
Belongs to the EBP2 family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisARBA annotationPhylogenomic databases
HOGENOMi | CLU_036007_1_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR008610, Ebp2 |
PANTHERi | PTHR13028, PTHR13028, 1 hit |
Pfami | View protein in Pfam PF05890, Ebp2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6IB29-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDTPPLSDSE SESDESLVTD RELQDAFSRG LLKPGLNVVL EGPKKAVNDV
60 70 80 90 100
NGLKQCLAEF KRDLEWVERL DVTLGPVPEI GGSEAPAPQN KDQKAVDPED
110 120 130 140 150
DFQREMSFYR QAQAAVLAVL PRLHQLKVPT KRPTDYFAEM AKSDLQMQKI
160 170 180 190 200
RQKLQTKQAA MERSEKAKQL RALRKYGKKV QTEVLQKRQQ EKAHMMNAIK
210 220 230 240 250
KYQKGFSDKL DFLEGDQKPL AQRKKAGAKG QQMRKGPSAK RRYKNQKFGF
260 270 280 290 300
GGKKKGSKWN TRESYDDVSS FRAKTAHGRG LKRPGKKGSN KRPGKRTREK
MKNRTH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT006920 mRNA Translation: AAP35566.1 AK223455 mRNA Translation: BAD97175.1 AB451256 mRNA Translation: BAG70070.1 AB451381 mRNA Translation: BAG70195.1 CR456975 mRNA Translation: CAG33256.1 CH471059 Genomic DNA Translation: EAX07112.1 |
RefSeqi | NP_006815.2, NM_006824.2 |
Genome annotation databases
GeneIDi | 10969 |
KEGGi | hsa:10969 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT006920 mRNA Translation: AAP35566.1 AK223455 mRNA Translation: BAD97175.1 AB451256 mRNA Translation: BAG70070.1 AB451381 mRNA Translation: BAG70195.1 CR456975 mRNA Translation: CAG33256.1 CH471059 Genomic DNA Translation: EAX07112.1 |
RefSeqi | NP_006815.2, NM_006824.2 |
3D structure databases
SMRi | Q6IB29 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q6IB29, 1 interactor |
Proteomic databases
PRIDEi | Q6IB29 |
Protocols and materials databases
Antibodypediai | 18196, 127 antibodies |
DNASUi | 10969 |
Genome annotation databases
GeneIDi | 10969 |
KEGGi | hsa:10969 |
Organism-specific databases
CTDi | 10969 |
PharmGKBi | PA27586 |
VEuPathDBi | HostDB:ENSG00000117395.10 |
Phylogenomic databases
HOGENOMi | CLU_036007_1_0_1 |
Miscellaneous databases
BioGRID-ORCSi | 10969, 606 hits in 882 CRISPR screens |
ChiTaRSi | EBNA1BP2, human |
GenomeRNAii | 10969 |
Gene expression databases
Bgeei | ENSG00000117395, Expressed in right lobe of liver and 236 other tissues |
ExpressionAtlasi | Q6IB29, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR008610, Ebp2 |
PANTHERi | PTHR13028, PTHR13028, 1 hit |
Pfami | View protein in Pfam PF05890, Ebp2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6IB29_HUMAN | |
Accessioni | Q6IB29Primary (citable) accession number: Q6IB29 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | February 10, 2021 | |
This is version 126 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |