UniProtKB - Q6IAW1 (Q6IAW1_HUMAN)
Protein
Submitted name:
Epididymis secretory sperm binding protein
Gene
GABARAP
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- GABA receptor binding Source: Ensembl
- microtubule binding Source: Ensembl
GO - Biological processi
- autophagy Source: UniProtKB-KW
- microtubule cytoskeleton organization Source: Ensembl
- protein transport Source: Ensembl
Keywordsi
Molecular function | ReceptorImported |
Biological process | AutophagyUniRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Epididymis secretory sperm binding proteinImportedSubmitted name: GABA(A) receptor-associated proteinImportedSubmitted name: GABARAP proteinImportedSubmitted name: HCG1987397, isoform CRA_bImported |
Gene namesi | Name:GABARAPImported ORF Names:hCG_1987397Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000170296.9 |
Subcellular locationi
Cytoskeleton
- actin cytoskeleton Source: Ensembl
- axoneme Source: Ensembl
- microtubule associated complex Source: Ensembl
Endoplasmic reticulum
- smooth endoplasmic reticulum Source: Ensembl
Golgi apparatus
- Golgi apparatus Source: Ensembl
Lysosome
- lysosome Source: Ensembl
Plasma Membrane
- plasma membrane Source: Ensembl
Other locations
- cell body Source: Ensembl
- perinuclear region of cytoplasm Source: Ensembl
- sperm midpiece Source: Ensembl
Keywords - Cellular componenti
MembraneARBA annotationPTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Lipidationi | 116 | Phosphatidylethanolamine amidated glycineUniRule annotation | 1 |
Keywords - PTMi
LipoproteinUniRule annotationProteomic databases
MaxQBi | Q6IAW1 |
Expressioni
Gene expression databases
Bgeei | ENSG00000170296, Expressed in right testis and 114 other tissues |
ExpressionAtlasi | Q6IAW1, baseline and differential |
Interactioni
Binary interactionsi
Q6IAW1
With | #Exp. | IntAct |
---|---|---|
WDFY3 [Q8IZQ1] | 17 | EBI-10106927,EBI-1569256 |
GO - Molecular functioni
- GABA receptor binding Source: Ensembl
- microtubule binding Source: Ensembl
Protein-protein interaction databases
IntActi | Q6IAW1, 3 interactors |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
HOGENOMi | CLU_119276_0_0_1 |
OMAi | MTTMGQL |
OrthoDBi | 1508198at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004241, Atg8-like IPR029071, Ubiquitin-like_domsf |
PANTHERi | PTHR10969, PTHR10969, 1 hit |
Pfami | View protein in Pfam PF02991, Atg8, 1 hit |
SUPFAMi | SSF54236, SSF54236, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6IAW1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKFVYKEEHP FEKRRSEGEK IRKKYPDRVP VIVEKAPKAR IGDLDKKKYL
60 70 80 90 100
VPSDLTVGQF YFLIRKRIHL RAEDALFFFV NNVIPPTSAT MGQLYQEHHE
110
EDFFLYIAYS DESVYGL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC106748 mRNA Translation: AAI06749.1 BC106749 mRNA Translation: AAI06750.1 GQ891383 mRNA Translation: ADO22245.1 CR457043 mRNA Translation: CAG33324.1 CR542235 mRNA Translation: CAG47031.1 CH471108 Genomic DNA Translation: EAW90234.1 CH471108 Genomic DNA Translation: EAW90238.1 |
RefSeqi | NP_009209.1, NM_007278.1 |
Genome annotation databases
GeneIDi | 11337 |
KEGGi | hsa:11337 |
UCSCi | uc002gfb.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC106748 mRNA Translation: AAI06749.1 BC106749 mRNA Translation: AAI06750.1 GQ891383 mRNA Translation: ADO22245.1 CR457043 mRNA Translation: CAG33324.1 CR542235 mRNA Translation: CAG47031.1 CH471108 Genomic DNA Translation: EAW90234.1 CH471108 Genomic DNA Translation: EAW90238.1 |
RefSeqi | NP_009209.1, NM_007278.1 |
3D structure databases
SMRi | Q6IAW1 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q6IAW1, 3 interactors |
Proteomic databases
MaxQBi | Q6IAW1 |
Protocols and materials databases
Antibodypediai | 11841, 696 antibodies |
DNASUi | 11337 |
Genome annotation databases
GeneIDi | 11337 |
KEGGi | hsa:11337 |
UCSCi | uc002gfb.4, human |
Organism-specific databases
CTDi | 11337 |
PharmGKBi | PA28480 |
VEuPathDBi | HostDB:ENSG00000170296.9 |
Phylogenomic databases
HOGENOMi | CLU_119276_0_0_1 |
OMAi | MTTMGQL |
OrthoDBi | 1508198at2759 |
Miscellaneous databases
BioGRID-ORCSi | 11337, 58 hits in 998 CRISPR screens |
ChiTaRSi | GABARAP, human |
GenomeRNAii | 11337 |
Gene expression databases
Bgeei | ENSG00000170296, Expressed in right testis and 114 other tissues |
ExpressionAtlasi | Q6IAW1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR004241, Atg8-like IPR029071, Ubiquitin-like_domsf |
PANTHERi | PTHR10969, PTHR10969, 1 hit |
Pfami | View protein in Pfam PF02991, Atg8, 1 hit |
SUPFAMi | SSF54236, SSF54236, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6IAW1_HUMAN | |
Accessioni | Q6IAW1Primary (citable) accession number: Q6IAW1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | April 7, 2021 | |
This is version 148 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |