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Protein
Submitted name:

CDKN1B protein

Gene

CDKN1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
CDKN1B proteinImported
Submitted name:
Cyclin-dependent kinase inhibitor 1B (P27, Kip1), isoform CRA_aImported
Submitted name:
cDNA, FLJ92816, Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1)(CDKN1B), mRNAImported
Gene namesi
Name:CDKN1BImported
ORF Names:hCG_27692Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000111276.10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA105

PTM / Processingi

Proteomic databases

MaxQBiQ6I9V6
PRIDEiQ6I9V6

Expressioni

Gene expression databases

BgeeiENSG00000111276
ExpressionAtlasiQ6I9V6 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ6I9V6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili38 – 58Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4743 Eukaryota
ENOG410XXN5 LUCA
HOVERGENiHBG073988
KOiK06624
OMAiYPKPSAC

Family and domain databases

InterProiView protein in InterPro
IPR003175 CDI
IPR029843 CDKN1B
PANTHERiPTHR10265 PTHR10265, 1 hit
PTHR10265:SF9 PTHR10265:SF9, 1 hit
PfamiView protein in Pfam
PF02234 CDI, 1 hit

Sequencei

Sequence statusi: Complete.

Q6I9V6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR
60 70 80 90 100
DMEEASQRKW NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK
110 120 130 140 150
VPAQESQDVS GSRPAAPLIG APANSEDTHL VDPKTDPSDS QTGLAEQCAG
160 170 180 190
IRKRPATDDS STQNKRANRT EENVSDGSPN AGSVEQTPKK PGLRRRQT
Length:198
Mass (Da):22,073
Last modified:May 10, 2005 - v1
Checksum:i1118D58901CDF3FC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei198Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312461 mRNA Translation: BAG35368.1
AB451291 mRNA Translation: BAG70105.1
AB451423 mRNA Translation: BAG70237.1
CR457399 mRNA Translation: CAG33680.1
CH471094 Genomic DNA Translation: EAW96275.1
RefSeqiNP_004055.1, NM_004064.4
UniGeneiHs.238990

Genome annotation databases

GeneIDi1027
KEGGihsa:1027
UCSCiuc001rat.3 human

Similar proteinsi

Entry informationi

Entry nameiQ6I9V6_HUMAN
AccessioniPrimary (citable) accession number: Q6I9V6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 20, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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