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Protein

UvrABC system protein C

Gene

uvrC

Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciBTHU281309:G1G14-4327-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:BT9727_4255
OrganismiBacillus thuringiensis subsp. konkukian (strain 97-27)
Taxonomic identifieri281309 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001301 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002273991 – 594UvrABC system protein CAdd BLAST594

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ6HD05
SMRiQ6HD05
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 91GIY-YIGUniRule annotationAdd BLAST78
Domaini196 – 231UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279960
KOiK03703
OMAiLFPIRQC

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

Q6HD05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHEHLKEKLA ILPDQPGCYL MKDKQGTVIY VGKAKVLKNR VRSYFTGSHD
60 70 80 90 100
GKTLRLVGEI VDFEYIVTSS NLEALILELN LIKKHDPKYN IQLKDDKTYP
110 120 130 140 150
FIKITAEKQP RLLITRNVKK DKGKYFGPYP NAQSAHETKK LLDRMYPLRK
160 170 180 190 200
CSNMPDKVCL YYHMGQCLAP CVKEVTEEQN KEIVDEIIKF LNGGHKEVRS
210 220 230 240 250
ELETKMYEAS EKLEFERAKE LRDQIAHIDA IMEKQKMIMS DLVDRDVFGY
260 270 280 290 300
AVDKGWMCVQ VFFVRKGKLI ERDVSMFPIY DEPEEGFLTF IGQFYENSSH
310 320 330 340 350
FKPKEIVVPG SIDSELVERF LEVEATQPKR GKKKDLVELA NKNAKIALEE
360 370 380 390 400
KFYLIERDEE RTIKAVENLG KQLGIETPYR IEAFDNSNIQ GTNPVSAMIA
410 420 430 440 450
FIDGKPAKKE YRKYKIKTVQ GPDDYESMRE VVRRRYTRAL KEGLPLPDLI
460 470 480 490 500
IIDGGKGHLA AASDVLENEL GLYIPMAGLV KDDKHKTSHL IIGDPPEPVM
510 520 530 540 550
LERNSQEFYL LQRVQDEVHR FAITFHRQLH GKSVIQSALD DIPGIGDKRK
560 570 580 590
KVLLKHFGSL KKMKEASIEE FVEAGMPKNV AETIYTYLTD KKTL
Length:594
Mass (Da):68,370
Last modified:July 19, 2004 - v1
Checksum:iF1F30466B8876465
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017355 Genomic DNA Translation: AAT63725.1
RefSeqiWP_000544275.1, NC_005957.1
YP_038571.1, NC_005957.1

Genome annotation databases

EnsemblBacteriaiAAT63725; AAT63725; BT9727_4255
GeneIDi2854353
KEGGibtk:BT9727_4255
PATRICifig|281309.8.peg.4535

Similar proteinsi

Entry informationi

Entry nameiUVRC_BACHK
AccessioniPrimary (citable) accession number: Q6HD05
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: July 19, 2004
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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