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Entry version 103 (02 Dec 2020)
Sequence version 1 (19 Jul 2004)
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Protein

Paternally-expressed gene 3 protein

Gene

PEG3

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri451 – 473C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri555 – 577C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri668 – 690C2H2-type 4; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri884 – 906C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1859 – 1881C2H2-type 6; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1924 – 1946C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1980 – 2002C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2040 – 2062C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2097 – 2119C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2148 – 2170C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2312 – 2334C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2363 – 2385C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Paternally-expressed gene 3 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PEG3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002492271 – 2387Paternally-expressed gene 3 proteinAdd BLAST2387

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6H236

PRoteomics IDEntifications database

More...
PRIDEi
Q6H236

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at high levels in the cerebellum and at moderate levels in the testis and ovary.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Interacts with SIAH1A and SIAH2.

Interacts with TRAF2 (By similarity).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9913.ENSBTAP00000031689

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini44 – 126SCAN boxPROSITE-ProRule annotationAdd BLAST83
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati965 – 9731-19
Repeati974 – 9821-29
Repeati983 – 9913-19
Repeati1001 – 10092-19
Repeati1010 – 10184-19
Repeati1028 – 10363-29
Repeati1046 – 10542-29
Repeati1055 – 10634-29
Repeati1073 – 10813-39
Repeati1091 – 10991-39
Repeati1109 – 11172-39
Repeati1118 – 11264-39
Repeati1136 – 11441-49
Repeati1145 – 11532-49
Repeati1154 – 11622-59
Repeati1163 – 11711-59
Repeati1172 – 11801-69
Repeati1190 – 11982-69
Repeati1199 – 12071-79
Repeati1217 – 12254-49
Repeati1235 – 12431-89
Repeati1253 – 12612-79
Repeati1280 – 12882-89
Repeati1289 – 12971-99
Repeati1298 – 13062-99
Repeati1307 – 13152-109
Repeati1316 – 13241-109
Repeati1325 – 13332-119
Repeati1334 – 13421-119
Repeati1343 – 13512-129
Repeati1352 – 13601-129
Repeati1361 – 13691-139
Repeati1370 – 13781-149
Repeati1379 – 13872-139
Repeati1388 – 13961-159
Repeati1397 – 14051-169
Repeati1406 – 14141-179
Repeati1415 – 14231-189
Repeati1424 – 14321-199
Repeati1433 – 14411-209
Repeati1442 – 14501-219
Repeati1451 – 14591-229
Repeati1460 – 14681-239
Repeati1469 – 14771-249
Repeati1478 – 14861-259
Repeati1496 – 15041-269
Repeati1505 – 15131-279
Repeati1514 – 15221-289
Repeati1523 – 15311-299
Repeati1532 – 15401-309
Repeati1541 – 15491-319
Repeati1550 – 15581-329
Repeati1559 – 15671-339
Repeati1568 – 15761-349
Repeati1577 – 15851-359
Repeati1586 – 15941-369
Repeati1595 – 16031-379

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni965 – 160337 X 9 AA repeat of P-A-Q-T-X-Y-X-X-EAdd BLAST639

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi162 – 209Arg-richAdd BLAST48
Compositional biasi370 – 373Poly-Gly4
Compositional biasi981 – 1603Glu-richAdd BLAST623
Compositional biasi2176 – 2184Poly-Ala9

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The SCAN domain enables PEG3 homo- or heterodimerization to control gene expression in a combinatorial fashion.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri451 – 473C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri555 – 577C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri668 – 690C2H2-type 4; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri884 – 906C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1859 – 1881C2H2-type 6; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1924 – 1946C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1980 – 2002C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2040 – 2062C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2097 – 2119C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2148 – 2170C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2312 – 2334C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri2363 – 2385C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6H236

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07936, SCAN, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.4020.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003309, SCAN_dom
IPR038269, SCAN_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02023, SCAN, 1 hit
PF00096, zf-C2H2, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00431, SCAN, 1 hit
SM00355, ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50804, SCAN_BOX, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6H236-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLPPKSLSAT KPKKWAPNLY ELDSDLSEPD AVPGEGATDS EFFHQRFRNF
60 70 80 90 100
LYVEFIGPRK TLLKLRNLCL DWLQPEIRTK EEIIEVLVLE QYLSILPERI
110 120 130 140 150
KPWVYARKPE TCEKLVALLE DYEAMYEPED DNSSDTHSEG GMSRRAAESP
160 170 180 190 200
PPRPALPCCS ERERRRGRSR DMESRDRWPS VRSPRSRFHQ RDLALPLAER
210 220 230 240 250
AKEREHRRRD SLLDLDARSE EAVLYQDMVA LTEDRKPQNP IQDNMENYRK
260 270 280 290 300
LLSLGVQLAE DDGHSHMTQG HSARSKRSAY PSTSRGLKTA PETKKSAHRR
310 320 330 340 350
GICEAESSHG VIMEKFIKDV ARSSRSGRAR ESSERPHRLS RRAGGDWKEA
360 370 380 390 400
SFSRREAGAS ERGPEGGAFG GGGFSCGSDL VSKKRALERK RRYHFDAEGQ
410 420 430 440 450
GPVHDPRGGA RKRPFECGGE ARRAAKAAGA SSLSAPPAAP SQPLDFGAMP
460 470 480 490 500
YVCDECGRSF AVISEFVEHQ IVHTRESLYE YGESFIHSAA VSEAQSRPEG
510 520 530 540 550
ARRSEGAQAA GLAEHRGGQA QEHLRGSGDE EQDEPFLPSP TFSELQKMYG
560 570 580 590 600
KDKFYECKVC KETFLHSSAL IEHQKIHSHE DREKERSTGA VRRTPMLGEL
610 620 630 640 650
QRACGKEKRY ECKVCGETFH HSAALREHQK THGRGSPSEG RARAFEETFI
660 670 680 690 700
PGQSLKRRQK TYSKEKLYDF REGGDAFGRS SDFMEHQKIH SRKSYFDSRG
710 720 730 740 750
YEKPLLHSMS MPGSQKSHTI TRPPEDEDEE KAFTASSSPE DGQEARGYER
760 770 780 790 800
SAYERAILHS LAAFRPPRGL REDGEPSTYL SGLRDPPQKT PAWESPYAGG
810 820 830 840 850
RHSFFRSSVF YRASRPAPLD HLAGEGPSGW QRDGEASGPS SDGRQHQKAR
860 870 880 890 900
AKKKNIERKN YDASMMHSLH FGESQTFRPR ERFYECLECG EFFVRSSELA
910 920 930 940 950
EHQKIHNRKK LSGSKNYLRS VLRSLSSTDP QTSYQGQSVQ MSYPQEAAQT
960 970 980 990 1000
SYAELAAQTS YAEEPAQTSY AVEPAQTSYA EEPAQTSYTE APAEASYTEE
1010 1020 1030 1040 1050
PAQTSCIEEP AQTSYTNPAA ETSYAEEPAQ TSYTEAPAEA SYTEEPAQTS
1060 1070 1080 1090 1100
CIEEPAQTSY TNPAAETSYT EEPAQTSYTE APAEASGIEE PAQTNYTEES
1110 1120 1130 1140 1150
AEVSYTEEPS QTSCIEEPAQ TSYTDPAAET SYTEEPAQTS YTQEPAQTSC
1160 1170 1180 1190 1200
TEEPAQTSCT EEPAQTSYTQ EPAQTSYTKE PAEASYTEEP AQTSCIEEPA
1210 1220 1230 1240 1250
QTNYTKESAK ASYTEEPAQT SYTDPAAETS YTEEPAQTNY TVESAEASYT
1260 1270 1280 1290 1300
EEPSQTSCIE EPAQTSYTDS AADTSCTEEP AQTSCTEEPA QTSYTQEPAQ
1310 1320 1330 1340 1350
TSCTEEPAQT SCTEEPAQTS YTQEPAQTSC TEEPAQTSYT QEPAQTSCTE
1360 1370 1380 1390 1400
EPAQTSYTEE PAQTSYTEEP AQTSYTQEPA QTSCTEEPAQ TSYTEEPAQT
1410 1420 1430 1440 1450
SYTEEPAQTS YTQEPAQTSY TEEPAQTSYT EEPAQTSYAQ EPAQTSYAEE
1460 1470 1480 1490 1500
PAQTSYAEEP AQTSYAEEPA QTSYTQEPAQ TNYTEEPAEA SYTEEPAQTS
1510 1520 1530 1540 1550
YAEEPAQTSY PEEPAQTSYA EEPAQTSYAE EPAQTSYPEE PAQTSYTEEP
1560 1570 1580 1590 1600
AQTSYAKEPA QTSYPEEPAQ TSYAEEPAQT SYAEEPAQTS YAEEPAQTSY
1610 1620 1630 1640 1650
SEEPAQTRYT GNELRSDMRK NQLRPDMPRN QLRPVMPRNQ LRPDMPRNQP
1660 1670 1680 1690 1700
RPVILRNQLR PDMPRNQPRP VILRNQLRPD MLGNQLRPDM PGNQLRPDML
1710 1720 1730 1740 1750
REPPAETSYA ELVAQISYAE LVTPTSYAEL AAETGYFEPP AQTSYTEPAE
1760 1770 1780 1790 1800
TNYADPAAQV SFDEPPAEAS YADLAAEISY AELAAETSYA DLAAQISYDE
1810 1820 1830 1840 1850
PPAETSYAEL AAQISYSEPA DQTSYAELAA QTSYSEPLAQ TSYAELTSET
1860 1870 1880 1890 1900
SYCEQPVLNE CKECGECFAT VEDLGRHQKI YAREKFHDGK LFGEPVMQDL
1910 1920 1930 1940 1950
GLDGSPEEEL EEQEEPEEPE DSIYGCKDCG LGFADRADLR DHQKVHGREY
1960 1970 1980 1990 2000
LVDSREYTHP AVHMPPVSEY QKDCLGEQLY ECPACGESFV HSSFLFEHQK
2010 2020 2030 2040 2050
VHEQDQFYGH RRYEPFMQPL IVSPRRPQAP QKSAPAGVGP QCQVCGQDFI
2060 2070 2080 2090 2100
HASVLSEHAR GHAGEGLPDQ GQGGAGAAGP GPAPTEPQQD PGEEQRYECE
2110 2120 2130 2140 2150
TCGESFPSQA DLQEHMRVHE KGEPYDYGAA FVHTSFLTEP PKRDWPFYEC
2160 2170 2180 2190 2200
KDCGKSFIHS TILTKHQKLH LQEEGAAAAA AATAQEAEAN VLVPREVLRI
2210 2220 2230 2240 2250
QGSNVEAAEP EVEAAEPEVE AAEPEVEAAE PLGEAEGPEW EAAEPSGEAE
2260 2270 2280 2290 2300
QPHAEAEQPD MDADEPDGAG IEDPEERAEE PEGDDDEPDG AGIEDPEEEG
2310 2320 2330 2340 2350
EEQEIQVEEP YYDCGECGET FPSGAAYAEH LTAHASLVIL EPAGLYGEGA
2360 2370 2380
GGPEGGRPDD ELFKCDVCGQ LFSDRLSLAR HQNTHTG
Length:2,387
Mass (Da):264,828
Last modified:July 19, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i349F29E48C095958
GO
Isoform 2 (identifier: Q6H236-2)
Sequence is not available
Length:
Mass (Da):

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY427787 mRNA Translation: AAR97556.1

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY427787 mRNA Translation: AAR97556.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000031689

Proteomic databases

PaxDbiQ6H236
PRIDEiQ6H236

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
InParanoidiQ6H236

Family and domain databases

CDDicd07936, SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR003309, SCAN_dom
IPR038269, SCAN_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF02023, SCAN, 1 hit
PF00096, zf-C2H2, 5 hits
SMARTiView protein in SMART
SM00431, SCAN, 1 hit
SM00355, ZnF_C2H2, 12 hits
SUPFAMiSSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS50804, SCAN_BOX, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPEG3_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6H236
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: July 19, 2004
Last modified: December 2, 2020
This is version 103 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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