Nomo1

Functionⁱ

May antagonize Nodal signaling.By similarity

GO - Molecular functionⁱ

carbohydrate binding Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Nodal modulator 1Imported
Gene namesⁱ	Name:Nomo1Imported
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 7

Organism-specific databases

MGIⁱ	MGI:2385850 Nomo1

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	24 – 1150	ExtracellularSequence analysisAdd BLAST	1127
Transmembraneⁱ	1151 – 1167	HelicalSequence analysisAdd BLAST	17
Topological domainⁱ	1168 – 1214	CytoplasmicSequence analysisAdd BLAST	47

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 23	Sequence analysisAdd BLAST		23
ChainⁱPRO_0000396822	24 – 1214	Nodal modulator 1Sequence analysisAdd BLAST		1191

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	42	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	210	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	610	N-linked (GlcNAc...) asparagineSequence analysis	1
Modified residueⁱ	1196	PhosphoserineCombined sources	1
Modified residueⁱ	1197	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Glycoprotein, Phosphoprotein

Proteomic databases

EPDⁱ	Q6GQT9
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q6GQT9
PaxDbⁱ	Q6GQT9
PeptideAtlas More...PeptideAtlasⁱ	Q6GQT9
PRIDEⁱ	Q6GQT9

PTM databases

iPTMnetⁱ	Q6GQT9
PhosphoSitePlusⁱ	Q6GQT9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000030835 Expressed in 299 organ(s), highest expression level in tracheobronchial tree
Genevisibleⁱ	Q6GQT9 MM

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	229243, 2 interactors
IntActⁱ	Q6GQT9, 2 interactors
Molecular INTeraction database More...MINTⁱ	Q6GQT9
STRINGⁱ	10090.ENSMUSP00000033121

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6GQT9
SMRⁱ	Q6GQT9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	692 – 720	Sequence analysisAdd BLAST		29

Keywords - Domainⁱ

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG1948 Eukaryota ENOG410XTI0 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000000089
HOVERGENⁱ	HBG071511
InParanoidⁱ	Q6GQT9
OMAⁱ	GWSFEPE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0126
PhylomeDBⁱ	Q6GQT9
TreeFamⁱ	TF313696

Family and domain databases

InterProⁱ	View protein in InterPro IPR013784 Carb-bd-like_fold IPR008969 CarboxyPept-like_regulatory
SUPFAMⁱ	SSF49452 SSF49452, 3 hits SSF49464 SSF49464, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

Q6GQT9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRAGRCAAAL LLLLLSGAGR AIGSEDIVVG CGGFVKSDVE INYSLIEIKL 
        60         70         80         90        100
YTKHGTLKYQ TDCAPNNGYF MIPLYDKGDF ILKIEPPLGW SFEPTNVELR 
       110        120        130        140        150
VDGVSDICTK GGDINFLFTG FSVNGKVLSK GQPLGPAGVQ VSLRSTGADS 
       160        170        180        190        200
KIQSTVTQPG GKFAFFKVLP GDYEILATHP TWALKEASTT VRVTNSNANA 
       210        220        230        240        250
AGPLIVAGYN VSGSVRSDGE PMKGVKFLLF SSLVNKEDVL GCNVSPVSGF 
       260        270        280        290        300
QPPDESLVYL CYAVSKEDGS FSFYSLPSGG YTVVPFYRGE RITFDVAPSR 
       310        320        330        340        350
LDFTVEHDSL RIEPVFHVMG FSVTGRVLNG PDGEGVPEAV VTLNNQIKVK 
       360        370        380        390        400
TKADGSFRLE NITTGTYTIH AQKEHLYFEM VTIKIAPNTP QLADLIATGF 
       410        420        430        440        450
SICGQIAIVR SPDTIKQMSK YRVVLSSQDK DKALLTVDSD AHGSFCFKAK 
       460        470        480        490        500
PGAYKVQVVV PEAETRAGLM LKPQVFPLTV TNRPVMDVAF VQFLASVSGK 
       510        520        530        540        550
VSCLDTCGDL LVTLQSLSRQ GEKRSLQLSG KVNSMTFTFD KVLPGRYKIS 
       560        570        580        590        600
IMHEDWCWRN KSLEVEVLED DVSAVEFRQT GYMLRCALSH AITLEFHQDG 
       610        620        630        640        650
NGPENVGIYN LSRGVNRFCL SKPGVYKVTP RSCHRFEQAF YTYDTSSPSI 
       660        670        680        690        700
LTLTAIRHHV LGTIITDKMM DVTVTIKSSI DSEPALVLGP LKSAQELRRE 
       710        720        730        740        750
QQLAEIETRR QEREKNGKEE GEEGRARPPG QEMVDELQGP FSYDFSYWAR 
       760        770        780        790        800
SGEKITVTPS SKELLFYPPS MEATVSGESC PGKLIEIHGK AGLFLEGQIH 
       810        820        830        840        850
PELEGVEIVI SEKGASSPLI TVFTDDKGAY SVGPLHSDLE YTVNSQKEGY 
       860        870        880        890        900
VLTAVEGTVG DFKAYALAGV SFEIKAEDDQ PLPGVLLSLS GGVFRSNLLT 
       910        920        930        940        950
QDNGILTFSN LSPGQYYFKP MMKEFRFEPS SQMIEVQEGQ NLRITITGFR 
       960        970        980        990       1000
TAYSCYGTVS SLNGEPEQGV AVEAVGQKDC SIYGEDTVTD EEGKFRLRGL 
      1010       1020       1030       1040       1050
LPGCMYHVQL KAEGNDHIER ALPHHRVIEV GNNDVDDVNI IVFRQINQFD 
      1060       1070       1080       1090       1100
LSGNVITSSE YLSTLWVKLY KSESLDNPIQ TVSLGQSLFF HFPPLLRDGE 
      1110       1120       1130       1140       1150
NYVVLLDTTL PRSQYDYVLP QVSFTAVGYH KHITLVFSPT RKLPEQDIAQ 
      1160       1170       1180       1190       1200
GSYIALPLTL LLLLAGYNHD KLIPLLLQLT SRLQGVRALG QAASDSSGPE 
      1210 
DMKRQTKKQK TRRT

Length:1,214

Mass (Da):133,420

Last modified:July 19, 2004 - v1

Checksum:ⁱ0F71587617C444A7

GO

Sequence cautionⁱ

The sequence AAH24503 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence AAH33923 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence BAC38713 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	6	C → G in BAC38508 (PubMed:16141072).Curated	1
Sequence conflictⁱ	62 – 63	DC → GW in BAC38508 (PubMed:16141072).Curated	2
Sequence conflictⁱ	75	Y → V in BAC38508 (PubMed:16141072).Curated	1
Sequence conflictⁱ	95 – 97	TNV → PHG in BAC38508 (PubMed:16141072).Curated	3
Sequence conflictⁱ	101	V → G in BAC38508 (PubMed:16141072).Curated	1
Sequence conflictⁱ	109	T → A in BAC38508 (PubMed:16141072).Curated	1
Sequence conflictⁱ	113	D → G in BAC38508 (PubMed:16141072).Curated	1
Sequence conflictⁱ	477	P → T in BAC38508 (PubMed:16141072).Curated	1
Sequence conflictⁱ	875 – 878	KAED → GRVG in AAH24503 (PubMed:15489334).Curated	4
Sequence conflictⁱ	1029	E → G in BAC31513 (PubMed:16141072).Curated	1
Sequence conflictⁱ	1176	L → V in BAC31513 (PubMed:16141072).Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK043279 mRNA Translation: BAC31513.1 AK082495 mRNA Translation: BAC38508.1 AK082963 mRNA Translation: BAC38713.1 Different initiation. AK166764 mRNA Translation: BAE39002.1 BC024503 mRNA Translation: AAH24503.1 Different initiation. BC033923 mRNA Translation: AAH33923.1 Different initiation. BC072630 mRNA Translation: AAH72630.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS21273.1
NCBI Reference Sequences More...RefSeqⁱ	NP_694697.3, NM_153057.4
UniGeneⁱ	Mm.274811

Genome annotation databases

Ensemblⁱ	ENSMUST00000033121; ENSMUSP00000033121; ENSMUSG00000030835
GeneIDⁱ	211548
KEGGⁱ	mmu:211548
UCSC genome browser More...UCSCⁱ	uc009gyb.2 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q6GQT9	Uncharacterized protein (Fragment)		Daphnia magna		120	UniRef100_Q6GQT9

Protein	Similar proteins		Species	Score	Length	Source
Q6GQT9	Uncharacterized protein (Fragment)		Daphnia magna		120	UniRef90_Q6GQT9
Nodal modulator 1		RAT		1214
nodal modulator 1		MESAU		1214
Uncharacterized protein		MACMU		1169
Uncharacterized protein		PROCO		1167
+11

Protein	Similar proteins		Species	Score	Length	Source
Q6GQT9	Nodal modulator 1		HUMAN		1222	UniRef50_Q15155
Uncharacterized protein		MACNE		1273
NOMO1 isoform 5 (Fragment)		PONAB		143
Uncharacterized protein		PANTR		1267
Uncharacterized protein		SHEEP		1267
+415

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK043279 mRNA Translation: BAC31513.1 AK082495 mRNA Translation: BAC38508.1 AK082963 mRNA Translation: BAC38713.1 Different initiation. AK166764 mRNA Translation: BAE39002.1 BC024503 mRNA Translation: AAH24503.1 Different initiation. BC033923 mRNA Translation: AAH33923.1 Different initiation. BC072630 mRNA Translation: AAH72630.1
CCDSⁱ	CCDS21273.1
RefSeqⁱ	NP_694697.3, NM_153057.4
UniGeneⁱ	Mm.274811

3D structure databases

ProteinModelPortalⁱ	Q6GQT9
SMRⁱ	Q6GQT9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	229243, 2 interactors
IntActⁱ	Q6GQT9, 2 interactors
MINTⁱ	Q6GQT9
STRINGⁱ	10090.ENSMUSP00000033121

PTM databases

iPTMnetⁱ	Q6GQT9
PhosphoSitePlusⁱ	Q6GQT9

Proteomic databases

EPDⁱ	Q6GQT9
MaxQBⁱ	Q6GQT9
PaxDbⁱ	Q6GQT9
PeptideAtlasⁱ	Q6GQT9
PRIDEⁱ	Q6GQT9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000033121; ENSMUSP00000033121; ENSMUSG00000030835
GeneIDⁱ	211548
KEGGⁱ	mmu:211548
UCSCⁱ	uc009gyb.2 mouse

Organism-specific databases

CTDⁱ	23420
MGIⁱ	MGI:2385850 Nomo1

Phylogenomic databases

eggNOGⁱ	KOG1948 Eukaryota ENOG410XTI0 LUCA
GeneTreeⁱ	ENSGT00390000000089
HOVERGENⁱ	HBG071511
InParanoidⁱ	Q6GQT9
OMAⁱ	GWSFEPE
OrthoDBⁱ	EOG091G0126
PhylomeDBⁱ	Q6GQT9
TreeFamⁱ	TF313696

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q6GQT9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000030835 Expressed in 299 organ(s), highest expression level in tracheobronchial tree
Genevisibleⁱ	Q6GQT9 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR013784 Carb-bd-like_fold IPR008969 CarboxyPept-like_regulatory
SUPFAMⁱ	SSF49452 SSF49452, 3 hits SSF49464 SSF49464, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	NOMO1_MOUSE
Accessionⁱ	Q6GQT9Primary (citable) accession number: Q6GQT9 Secondary accession number(s): Q3TKZ1 , Q8BJM1, Q8BJM8, Q8BLS9, Q8K074, Q8R1I7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 10, 2010
	Last sequence update:	July 19, 2004
	Last modified:	September 12, 2018
	This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6GQT9 (NOMO1_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Nodal modulator 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Endoplasmic reticulum

Other locations

Topology

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ