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Entry version 128 (02 Jun 2021)
Sequence version 1 (19 Jul 2004)
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Protein

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

Gene

ITPRIPL1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6GPH6

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q6GPH6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ITPRIPL1
Synonyms:KIAA1754L
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29371, ITPRIPL1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6GPH6

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000198885.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini25 – 103ExtracellularSequence analysisAdd BLAST79
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Topological domaini125 – 555CytoplasmicSequence analysisAdd BLAST431

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
150771

Open Targets

More...
OpenTargetsi
ENSG00000198885

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162392345

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6GPH6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ITPRIPL1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74736480

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000032056625 – 555Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1Add BLAST531

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6GPH6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6GPH6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6GPH6

PeptideAtlas

More...
PeptideAtlasi
Q6GPH6

PRoteomics IDEntifications database

More...
PRIDEi
Q6GPH6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
25696
66314 [Q6GPH6-1]
66315 [Q6GPH6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6GPH6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6GPH6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198885, Expressed in testis and 129 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6GPH6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6GPH6, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000198885, Tissue enhanced (blood, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
127325, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q6GPH6, 10 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000355121

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6GPH6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili38 – 74Sequence analysisAdd BLAST37

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ITPRIP family.Curated

Keywords - Domaini

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RX8U, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00980000198551

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_025485_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6GPH6

Database of Orthologous Groups

More...
OrthoDBi
1434451at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6GPH6

TreeFam database of animal gene trees

More...
TreeFami
TF332277

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024808, IP3R-int-like_1
IPR026250, ITPRIP_fam
IPR024810, Mab-21_dom

The PANTHER Classification System

More...
PANTHERi
PTHR10656:SF40, PTHR10656:SF40, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03281, Mab-21, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR02107, INOS145TPRIP

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01265, Mab-21, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6GPH6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNVDAEASMA VISLLFLAVM YVVHHPLMVS DRMDLDTLAR SRQLEKRMSE
60 70 80 90 100
EMRLLEMEFE ERKRAAEQRQ KAENFWTGDT SSDQLVLGKK DMGWPFQADG
110 120 130 140 150
QEGPLGWMLG NLWNTGLFCL FLVFELLRQN MQHEPAFDSS SEEEEEEVRV
160 170 180 190 200
VPVTSYNWLT DFPSQEALDS FYKHYVQNAI RDLPCTCEFV ESFVDDLIEA
210 220 230 240 250
CRVLSRQEAH PQLEDCLGIG AAFEKWGTLH ETQKFDILVP IVPPQGTMFV
260 270 280 290 300
LEMRDPALGR RCGCVLVESE CVCKREKLLG DVLCLVHHHR DPSAVLGKCS
310 320 330 340 350
SSIKAALCTG FHLDVCKTVQ WFRNMMGNAW ALVAHKYDFK LSLPPSTTSC
360 370 380 390 400
KLRLDYRSGR FLSIHLVLGV QREDTLVYLV SQAPDQEQLT SVDWPESFVA
410 420 430 440 450
CEHLFLKLVG RFAPENTCHL KCLQIILSLR QHQSLPHGAS RPILTSYHFK
460 470 480 490 500
TALMHLLLRL PLTDWAHNML SQRLQDILWF LGRGLQQRSL HHFLIGNNFL
510 520 530 540 550
PLTIPIPKTF RNAEPVNLFQ HLVLNPKAHS QAVEEFQNLL TQVKTLPHAP

LAAAP
Length:555
Mass (Da):63,395
Last modified:July 19, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6B915F09A1ACEBFF
GO
Isoform 2 (identifier: Q6GPH6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-3: MNV → MTTDSYSPTSP

Show »
Length:563
Mass (Da):64,219
Checksum:i7CBCDD2B8075EF81
GO
Isoform 3 (identifier: Q6GPH6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-8: Missing.

Show »
Length:547
Mass (Da):62,577
Checksum:iAB4B8DB0283FEA53
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JNT4C9JNT4_HUMAN
Inositol 1,4,5-trisphosphate recept...
ITPRIPL1
180Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C0T2H7C0T2_HUMAN
Inositol 1,4,5-trisphosphate recept...
ITPRIPL1
587Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_039209280G → R1 PublicationCorresponds to variant dbSNP:rs17853311Ensembl.1
Natural variantiVAR_039210428S → C. Corresponds to variant dbSNP:rs35855657Ensembl.1
Natural variantiVAR_039211463T → M. Corresponds to variant dbSNP:rs2279105Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0543161 – 8Missing in isoform 3. Curated8
Alternative sequenceiVSP_0316661 – 3MNV → MTTDSYSPTSP in isoform 2. 1 Publication3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC021188 Genomic DNA No translation available.
BC034503 mRNA Translation: AAH34503.2
BC073153 mRNA Translation: AAH73153.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33250.1 [Q6GPH6-2]
CCDS46360.1 [Q6GPH6-1]
CCDS54378.1 [Q6GPH6-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001008949.1, NM_001008949.2 [Q6GPH6-1]
NP_001156995.1, NM_001163523.1 [Q6GPH6-3]
NP_001156996.1, NM_001163524.1 [Q6GPH6-3]
NP_001311419.1, NM_001324490.1 [Q6GPH6-3]
NP_848590.3, NM_178495.5 [Q6GPH6-2]
XP_016858916.1, XM_017003427.1 [Q6GPH6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361124; ENSP00000355121; ENSG00000198885 [Q6GPH6-2]
ENST00000439118; ENSP00000389308; ENSG00000198885 [Q6GPH6-1]
ENST00000536814; ENSP00000439566; ENSG00000198885 [Q6GPH6-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
150771

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:150771

UCSC genome browser

More...
UCSCi
uc002svx.4, human [Q6GPH6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021188 Genomic DNA No translation available.
BC034503 mRNA Translation: AAH34503.2
BC073153 mRNA Translation: AAH73153.1
CCDSiCCDS33250.1 [Q6GPH6-2]
CCDS46360.1 [Q6GPH6-1]
CCDS54378.1 [Q6GPH6-3]
RefSeqiNP_001008949.1, NM_001008949.2 [Q6GPH6-1]
NP_001156995.1, NM_001163523.1 [Q6GPH6-3]
NP_001156996.1, NM_001163524.1 [Q6GPH6-3]
NP_001311419.1, NM_001324490.1 [Q6GPH6-3]
NP_848590.3, NM_178495.5 [Q6GPH6-2]
XP_016858916.1, XM_017003427.1 [Q6GPH6-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi127325, 18 interactors
IntActiQ6GPH6, 10 interactors
STRINGi9606.ENSP00000355121

PTM databases

iPTMnetiQ6GPH6
PhosphoSitePlusiQ6GPH6

Genetic variation databases

BioMutaiITPRIPL1
DMDMi74736480

Proteomic databases

EPDiQ6GPH6
MassIVEiQ6GPH6
PaxDbiQ6GPH6
PeptideAtlasiQ6GPH6
PRIDEiQ6GPH6
ProteomicsDBi25696
66314 [Q6GPH6-1]
66315 [Q6GPH6-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
3069, 106 antibodies

The DNASU plasmid repository

More...
DNASUi
150771

Genome annotation databases

EnsembliENST00000361124; ENSP00000355121; ENSG00000198885 [Q6GPH6-2]
ENST00000439118; ENSP00000389308; ENSG00000198885 [Q6GPH6-1]
ENST00000536814; ENSP00000439566; ENSG00000198885 [Q6GPH6-3]
GeneIDi150771
KEGGihsa:150771
UCSCiuc002svx.4, human [Q6GPH6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
150771
DisGeNETi150771

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ITPRIPL1
HGNCiHGNC:29371, ITPRIPL1
HPAiENSG00000198885, Tissue enhanced (blood, testis)
neXtProtiNX_Q6GPH6
OpenTargetsiENSG00000198885
PharmGKBiPA162392345
VEuPathDBiHostDB:ENSG00000198885.9

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RX8U, Eukaryota
GeneTreeiENSGT00980000198551
HOGENOMiCLU_025485_2_0_1
InParanoidiQ6GPH6
OrthoDBi1434451at2759
PhylomeDBiQ6GPH6
TreeFamiTF332277

Enzyme and pathway databases

PathwayCommonsiQ6GPH6
SIGNORiQ6GPH6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
150771, 4 hits in 985 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
150771
PharosiQ6GPH6, Tdark

Protein Ontology

More...
PROi
PR:Q6GPH6
RNActiQ6GPH6, protein

Gene expression databases

BgeeiENSG00000198885, Expressed in testis and 129 other tissues
ExpressionAtlasiQ6GPH6, baseline and differential
GenevisibleiQ6GPH6, HS

Family and domain databases

InterProiView protein in InterPro
IPR024808, IP3R-int-like_1
IPR026250, ITPRIP_fam
IPR024810, Mab-21_dom
PANTHERiPTHR10656:SF40, PTHR10656:SF40, 1 hit
PfamiView protein in Pfam
PF03281, Mab-21, 1 hit
PRINTSiPR02107, INOS145TPRIP
SMARTiView protein in SMART
SM01265, Mab-21, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIPIL1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6GPH6
Secondary accession number(s): F5H1L8, Q8NE61
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 19, 2004
Last modified: June 2, 2021
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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