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Protein

Serine/threonine-protein phosphatase 1 regulatory subunit 10

Gene

ppp1r10

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable inhibitor of phosphatase activity.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri785 – 813C3H1-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

Keywordsi

Molecular functionProtein phosphatase inhibitor
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 1 regulatory subunit 10
Gene namesi
Name:ppp1r10
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6254587 ppp1r10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000715161 – 819Serine/threonine-protein phosphatase 1 regulatory subunit 10Add BLAST819

Proteomic databases

PRIDEiQ6GLQ4

Structurei

3D structure databases

ProteinModelPortaliQ6GLQ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 147TFIIS N-terminalPROSITE-ProRule annotationAdd BLAST75

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi412 – 415PP1-binding motif4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi661 – 783Gly-richAdd BLAST123

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri785 – 813C3H1-typePROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOVERGENiHBG053646
KOiK17552

Family and domain databases

Gene3Di1.20.930.10, 1 hit
InterProiView protein in InterPro
IPR003617 TFIIS/CRSP70_N_sub
IPR035441 TFIIS/LEDGF_dom_sf
IPR017923 TFIIS_N
IPR000571 Znf_CCCH
PfamiView protein in Pfam
PF08711 Med26, 1 hit
SMARTiView protein in SMART
SM00509 TFS2N, 1 hit
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF47676 SSF47676, 1 hit
PROSITEiView protein in PROSITE
PS51319 TFIIS_N, 1 hit
PS50103 ZF_C3H1, 1 hit

Sequencei

Sequence statusi: Complete.

Q6GLQ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSGPIDPLE LLKGLDNILG QGGEVKALEG MAKIFNLMKQ SQKMVNRCIY
60 70 80 90 100
LNIVLQTHSP DILSKFIRVG GYKLLNNWLT YARTCNNSPL LHQILLTLQH
110 120 130 140 150
LPLTVDHLKQ NNTAKLVKQL SKSSEDEELR KLAGILVNDW MAVIRSQTNI
160 170 180 190 200
QPADKEKKKK KEDAKGSSPV LDKTSEAKSE DNGDKKEKPK IQRTTAPSHA
210 220 230 240 250
KFRSTGLEVE ASSLVPVKKP TPVPVLSDKY LKPVPVKRQS SVPVPGDAAP
260 270 280 290 300
AEKKYKPLNI VPNTTKEIKV KIIPPQPIES LGFLDALNSA PVPGIKIKKK
310 320 330 340 350
KKAVSPTSNK ASPFDSKSPT EASSLTKPSS PEPEPPVEGM EVERPGTPVP
360 370 380 390 400
AIELPEPMEI SAPPPPAPSE TKPSEADASQ LTKKGKKRKT VSWPEESRLR
410 420 430 440 450
EYFYFELDET ERVNVNKIKD FGEAAKREML KDRQAFQNAR RHSHDTMEEV
460 470 480 490 500
IPWVLPRLLN LPGALVQMGS NSTEKHAQAE REMGILQEIF LSKESVPDTP
510 520 530 540 550
HEPDPESYEP SPPKLIPLDE DCSMDDGVYP ESMDQSTESQ SPDLNGAKLP
560 570 580 590 600
PVLANLMGSM GSSKSPPNTL PGTMQEILTS IMGAQGNAKP EDLMKQPDFS
610 620 630 640 650
EKIKHLLGSL QNQNQNQGPP GPAGQGSQGP VNIGFPPPSQ KNHQPPPPHH
660 670 680 690 700
QPPPPHYPPP GPNGPFQGPH GPPGGPRMMG PPPPQRDGYW EPPPNENLRG
710 720 730 740 750
GSHHGGERGG MRGGDRGPPP PPFHRNRGGR GGEPGYRGRG RGGERGHPGR
760 770 780 790 800
NGPYGMGHGD HRGHEGHRGH GGHGDHRGHG HGGDMSTRPT CRHFMMKGNC
810
RYENNCAFYH PGINGPPLP
Length:819
Mass (Da):89,326
Last modified:July 19, 2004 - v1
Checksum:i7181CDA100215A6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC074405 mRNA Translation: AAH74405.1
RefSeqiNP_001086267.1, NM_001092798.1
UniGeneiXl.11257

Genome annotation databases

GeneIDi444696
KEGGixla:444696

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC074405 mRNA Translation: AAH74405.1
RefSeqiNP_001086267.1, NM_001092798.1
UniGeneiXl.11257

3D structure databases

ProteinModelPortaliQ6GLQ4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ6GLQ4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi444696
KEGGixla:444696

Organism-specific databases

CTDi444696
XenbaseiXB-GENE-6254587 ppp1r10

Phylogenomic databases

HOVERGENiHBG053646
KOiK17552

Family and domain databases

Gene3Di1.20.930.10, 1 hit
InterProiView protein in InterPro
IPR003617 TFIIS/CRSP70_N_sub
IPR035441 TFIIS/LEDGF_dom_sf
IPR017923 TFIIS_N
IPR000571 Znf_CCCH
PfamiView protein in Pfam
PF08711 Med26, 1 hit
SMARTiView protein in SMART
SM00509 TFS2N, 1 hit
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF47676 SSF47676, 1 hit
PROSITEiView protein in PROSITE
PS51319 TFIIS_N, 1 hit
PS50103 ZF_C3H1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPP1RA_XENLA
AccessioniPrimary (citable) accession number: Q6GLQ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: July 19, 2004
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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