Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

S-adenosylmethionine mitochondrial carrier protein

Gene

slc25a26

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S-adenosylmethionine (SAM) into the mitochondria (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
S-adenosylmethionine mitochondrial carrier protein
Alternative name(s):
Mitochondrial S-adenosylmethionine transporter
Solute carrier family 25 member 26
Gene namesi
Name:slc25a26
Synonyms:samc
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-991471 slc25a26

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei5 – 25Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei49 – 69Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei84 – 104Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei141 – 161Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei181 – 201Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei237 – 257Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003175911 – 269S-adenosylmethionine mitochondrial carrier proteinAdd BLAST269

Proteomic databases

PaxDbiQ6GLA2
PRIDEiQ6GLA2

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000056365

Structurei

3D structure databases

ProteinModelPortaliQ6GLA2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati4 – 77Solcar 1Add BLAST74
Repeati85 – 167Solcar 2Add BLAST83
Repeati176 – 264Solcar 3Add BLAST89

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0768 Eukaryota
ENOG4110BII LUCA
HOGENOMiHOG000038810
HOVERGENiHBG108456
InParanoidiQ6GLA2
KOiK15111

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 4 hits
PRINTSiPR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q6GLA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERREFCASL LAGGTAGMCV DLILFPLDTI KTRLQSPLGF SKSGGFRGIY
60 70 80 90 100
AGVPSTAVGS FPNAAAFFVT YESAKQLLRS DSSYLSPIIH MAAASLGEVV
110 120 130 140 150
ACLIRVPSEV IKQRAQVSPS STTYQMLSAT LRQEGIKGLY RGYKSTVLRE
160 170 180 190 200
IPFSLVQFPL WESLKDLWSW KQGRAVDSWQ SAVCGAFAGG FAAALTTPLD
210 220 230 240 250
VAKTRIMLAK AGSGVASGNV LFALHEIWRT QGIMGLFAGV IPRMTAISLG
260
GFIFLGAYDK VRTLMLREQ
Length:269
Mass (Da):29,020
Last modified:July 19, 2004 - v1
Checksum:iD23A798DCDDE1863
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC074600 mRNA Translation: AAH74600.1
RefSeqiNP_001004820.1, NM_001004820.1
UniGeneiStr.52379

Genome annotation databases

GeneIDi448074
KEGGixtr:448074

Similar proteinsi

Entry informationi

Entry nameiSAMC_XENTR
AccessioniPrimary (citable) accession number: Q6GLA2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 19, 2004
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health